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Inflammatory disorders news

Medications

Phase III success for rocatinlimab in moderate-to-severe eczema

An international team of investigators has reported results from the first Phase III clinical trials of rocatinlimab, a novel treatment for moderate-to-severe atopic dermatitis (eczema).

Health

Eye washing may ease hay fever ocular symptoms and improve quality of life

Hay fever, also known as allergic rhinitis, is the condition responsible for seasonal allergies or allergic reactions to other environmental allergens, like dust mites and animal dander. Estimates vary, but somewhere around ...

Inflammatory disorders

Chronic pruritus prevalent among older adults

Chronic pruritus is prevalent among older adults and is associated with moderately impaired pruritus-specific quality of life, according to a study published online Nov. 10 in Acta Dermato Venereologica.

Immunology

Certain immune cell subtypes drive lupus, study finds

Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by Weill Cornell Medicine ...

Inflammatory disorders

Are peanut allergies actually declining?

Peanut allergy is one of the most common food allergies, affecting between 1% and 2% of people living in the West. And, for many years, their prevalence has been rising.

Diseases, Conditions, Syndromes

How viruses can cause long-term lung damage

University of Manchester biologists have for the first time started to unpick the long-term biological changes associated with serious viral lung infections, such as flu and long COVID, in a study of mice.

Inflammatory disorders

Hoping to enjoy your holidays? Avoid the sneeze and wheeze triggers

As families prepare to celebrate Thanksgiving, Hanukkah, Christmas, and other winter holidays, millions will also have to navigate increased exposure to allergy and asthma triggers. From festive decorations to candle lightings ...

Health

Air pollution can have harmful effects on your lung health

We are exposed to air pollution daily. When we step outside, we inhale pollutants from particulate matter (such as smoke or dust), burning fossil fuels, wildfires and more. For Lung Cancer Awareness Month, medical professionals ...

Genetics

New potential gene-based treatment for sepsis and lung injury

A new discovery from the lab of YouYang Zhao, Ph.D., from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, opens promising new directions for treatment of life-threatening ...

Genetics

Molecule that could cause COVID clotting key to new treatments

In a surprising discovery, a "sticky molecule" that occurs naturally in our blood vessels could be both a culprit behind blood clots and organ failure during COVID and long COVID and the key to new treatments to counter COVID-related ...

Arthritis & Rheumatism

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Inflammatory disorders

Scientists map the cells that drive Crohn's disease fistulas

Scientists at the University of Oxford, have identified how rare populations of abnormal cells drive the formation and persistence of fistulas—painful, tunnel-like tracts that develop in around 30% of people with Crohn's ...

Diseases, Conditions, Syndromes

First death linked to 'meat allergy' spread by ticks

University of Virginia School of Medicine researchers have identified the first death caused by what is commonly called the "meat allergy" being spread by ticks.

Diseases, Conditions, Syndromes

Testing lung function earlier may help identify risk for COPD

Measuring lung function earlier in life would help identify people at risk of developing chronic obstructive pulmonary disease (COPD) and allow for more timely interventions, according to a new study published in the September ...

Inflammatory disorders

Icotrokinra beneficial for adults, teens with plaque psoriasis

For adults and adolescents with moderate-to-severe plaque psoriasis, selective blockade of the interleukin-23 receptor with the targeted oral peptide icotrokinra yields a significantly higher incidence of skin clearance at ...

Inflammatory disorders

Plants adapting to climate change may help IBD treatment

James Cook University (JCU) researchers have discovered that the same chemical compounds produced by mountain-top plants to help them survive climate change in North Queensland may also hold promise for treating inflammatory ...

Inflammatory disorders

Sleep issues linked to higher risk of severe asthma in children

About 30 to 40% of children with asthma experience sleep difficulties due to symptoms like coughing and wheezing. Poor sleep increases the risk of severe asthma exacerbations (attacks) that often necessitate a hospitalization ...

Immunology

A toast to BRD4: How acidity changes the immune response

It started with wine. Or more precisely, a conversation about it. "My colleagues and I were talking about how some people think drinking wine may be anti-inflammatory," recalls Xu Zhou, Ph.D., from the Division of Gastroenterology, ...

Oncology & Cancer

Lung cancer's earliest stages may be driven by inflammation

By creating high-resolution cellular and molecular visual maps of lung cancer before and during development, researchers at The University of Texas MD Anderson Cancer Center have discovered that the earliest stages of lung ...

HIV & AIDS

Low-dose THC may reduce side effects of HIV treatment

Long-term, low doses of THC mitigate many harmful side effects and inflammation caused by HIV and antiretroviral therapy (ART), according to new research from Texas Biomedical Research Institute.