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Inflammatory disorders news

Neuroscience

The role of neuroinflammation in progressive multiple sclerosis

Multiple sclerosis (MS) is a disorder that prompts the body's immune system to attack myelin, the protective sheath covering nerve cells in the brain, optic nerve and spinal cord. This can in turn result in vision impairments, ...

Immunology

Eczema injectable drug provides quick itch relief, clinical trial results show

A recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.

Immunology

Key lung immune cells can intensify allergic reactions

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...

Inflammatory disorders

Study finds why asthma drugs help some children but not others

Indiana University School of Medicine researchers are taking a closer look at how young patients respond to biologic treatments for asthma. By analyzing clinical parameters and identifying which children are still likely ...

Neuroscience

A fatal mix-up: How certain gut bacteria drive multiple sclerosis

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of multiple sclerosis, as ...

Inflammatory disorders

The role emotions play in inflammatory bowel disease

Many patients with inflammatory bowel disease (IBD) suffer from abdominal pain even between acute inflammatory flare-ups. Altered processing of pain in response to fear may be involved. This is the conclusion of a research ...

Immunology

New vulnerability of asthma immune cells discovered

Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered ...

Inflammatory disorders

Long-term efficacy for lebrikizumab seen in moderate, severe eczema

For patients with moderate-to-severe atopic dermatitis (AD), lebrikizumab has long-term efficacy, according to a study presented at the annual meeting of the European Academy of Dermatology and Venereology, held from Sept. ...

Neuroscience

Scientists use ribosomal tagging to study neuroinfections

Scientists study the functions of microglia by transcriptomics. This method provides dynamic information about genes that are active in the cell in both health and disease states. To do so, they isolate single cells from ...

Inflammatory disorders

Study highlights pervasiveness of inflammation in American diet

Almost 6 in 10 Americans have pro-inflammatory diets, increasing the risk of health problems including heart disease and cancer, according to a new study that used a tool designed to examine inflammation in the diet.

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

Home-based phototherapy as effective as office-based for psoriasis

For plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 in JAMA Dermatology to coincide with the annual ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.