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Inflammatory disorders news

Neuroscience

The role of neuroinflammation in progressive multiple sclerosis

Multiple sclerosis (MS) is a disorder that prompts the body's immune system to attack myelin, the protective sheath covering nerve cells in the brain, optic nerve and spinal cord. This can in turn result in vision impairments, ...

Immunology

Eczema injectable drug provides quick itch relief, clinical trial results show

A recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.

Immunology

Key lung immune cells can intensify allergic reactions

Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...

Inflammatory disorders

Study finds why asthma drugs help some children but not others

Indiana University School of Medicine researchers are taking a closer look at how young patients respond to biologic treatments for asthma. By analyzing clinical parameters and identifying which children are still likely ...

Neuroscience

A fatal mix-up: How certain gut bacteria drive multiple sclerosis

If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of multiple sclerosis, as ...

Inflammatory disorders

The role emotions play in inflammatory bowel disease

Many patients with inflammatory bowel disease (IBD) suffer from abdominal pain even between acute inflammatory flare-ups. Altered processing of pain in response to fear may be involved. This is the conclusion of a research ...

Immunology

New vulnerability of asthma immune cells discovered

Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered ...

Diseases, Conditions, Syndromes

Researchers test the systemic score for Still's disease

Still's disease is an inflammatory disorder typically manifesting with fever, arthritis, and skin rash. It affects both children and adults, and has previously been known as systemic juvenile idiopathic arthritis and adult-onset ...

Inflammatory disorders

Does inflammation in mid-life affect late-life mobility?

In a recent study published in the Journal of the American Geriatric Society, having high inflammation in midlife was associated with a clinically meaningful slower gait speed—an indicator of mobility—20 years later.

Inflammatory disorders

Major cause of inflammatory bowel disease discovered

Researchers at the Francis Crick Institute, working with UCL and Imperial College London, have discovered a new biological pathway that is a principal driver of inflammatory bowel disease (IBD) and related conditions, and ...

Genetics

New insights on cellular clones and inflammation in bones

As humans age, hematopoietic stem cells—the immature precursor cells that give rise to all blood and immune cells—accumulate mutations. Some of the mutations allow these stem cells to self-renew and expand more effectively ...

Immunology

New drug shows promise in easing chronic pain, study finds

A team of researchers from Virginia Commonwealth University, the University of Texas at Austin and the University of Virginia have made progress toward developing a drug candidate for treating chronic pain more safely.