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Inflammatory disorders news
Inflammatory disorders
Estrogen heightens gut pain sensitivity and may explain IBS gender gap
Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort. Now, scientists at UC San Francisco may have discovered ...
10 hours ago
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Immunology
Key lung immune cells can intensify allergic reactions
Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...
14 hours ago
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Obesity and inflammation may accelerate lung aging and increase the risk of COPD
A Brazilian study involving nearly 900 participants under the age of 40 reinforces the idea that premature lung aging is linked not only to smoking but also to factors such as obesity and systemic inflammation. These two ...
Dec 17, 2025
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Study finds why asthma drugs help some children but not others
Indiana University School of Medicine researchers are taking a closer look at how young patients respond to biologic treatments for asthma. By analyzing clinical parameters and identifying which children are still likely ...
Dec 17, 2025
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Harmless Klebsiella strain shows powerful protection against gut infections in inflammatory bowel disease model
A team of researchers led by Karina Xavier has uncovered a promising new live biotherapeutic agent that may redefine how the medical field approaches microbiota-based therapies.
Dec 16, 2025
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Little awareness of medical and psychological complexities of steroid cream withdrawal
There is little awareness, particularly among clinicians, of the medical and psychological complexities of "topical steroid withdrawal"—the body's adverse response to the prolonged use of these powerful creams to treat ...
Dec 16, 2025
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A fatal mix-up: How certain gut bacteria drive multiple sclerosis
If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of multiple sclerosis, as ...
Dec 15, 2025
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'Zombie' cells spark inflammation in severe fatty liver disease, researchers find
Mayo Clinic researchers have uncovered how aging "zombie cells" trigger harmful inflammation that accelerates a severe and increasingly common form of fatty liver disease called metabolic dysfunction-associated steatohepatitis ...
Dec 15, 2025
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Persistent inflammation in older adults tied to GDF3 protein signaling
As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis. New research from University of Minnesota researchers reveals how certain immune ...
Dec 15, 2025
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Mpox inflammation traced to AIM2 protein: New insights into immune overdrive
A team of researchers, affiliated with UNIST, has identified a protein sensor that plays a key role in triggering severe inflammatory responses during mpox virus (MPXV) infection. The study reveals that this protein, known ...
Dec 15, 2025
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The role emotions play in inflammatory bowel disease
Many patients with inflammatory bowel disease (IBD) suffer from abdominal pain even between acute inflammatory flare-ups. Altered processing of pain in response to fear may be involved. This is the conclusion of a research ...
Dec 12, 2025
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Psoriasis study shows link between fat metabolism and skin inflammation for first time
A research team led by Erwin F. Wagner from the Medical University of Vienna has discovered a previously unknown molecular mechanism that contributes to the development of psoriasis—and at the same time represents a potential ...
Dec 11, 2025
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New vulnerability of asthma immune cells discovered
Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered ...
Dec 11, 2025
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Allergy risk varies by region: IgE profiles highlight environmental influence and hypoallergenic region
Allergic sensitization follows distinct regional patterns, and molecular IgE profiling can reveal these profiles in detail. An international research team has now demonstrated both phenomena in a population-based study of ...
Dec 11, 2025
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Canadian wildfire smoke worsened pediatric asthma in US Northeast, study shows
New research from the University of Vermont reveals exposure to smoke from Canadian wildfires in the summer of 2023 led to worsening asthma symptoms in children in Vermont and upstate New York.
Dec 11, 2025
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Ticked off: Exploring the rise of tick-induced meat allergy and its connection to cardiovascular disease
Mammalian meat allergy (MMA) is one of the few known food allergies caused by an environmental trigger—a tick bite. In simple terms, MMA results in an allergic reaction to red meat, making it difficult or sometimes even ...
Dec 11, 2025
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Key protein behind necroptotic cell death could drive new treatment strategies
Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their findings, reported in Nature, ...
Dec 10, 2025
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Immune 'switch' identified as a potential target to curb chronic inflammation in cirrhosis
Chronic liver inflammation is one of the most serious complications associated with liver cirrhosis. Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified a molecular mechanism that acts as ...
Dec 10, 2025
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A subset of patients with depression could benefit from anti-inflammatory treatment, study finds
At any given moment in time, more than 400 million individuals worldwide are battling depression. The antidepressant treatments currently available don't work for many and there is a real need for new, effective treatments.
Dec 10, 2025
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Simple ways to reduce inflammation and protect your heart
If you've ever fought off an infection or iced a sprained knee, you know something about inflammation. But you might not know its importance to heart and brain health.
Dec 9, 2025
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Managing food allergies and dietary restrictions during the holidays
A plate of freshly baked cookies, a glass of perfectly garnished eggnog. For many, these images may conjure up warm memories and the anticipation of the forthcoming holiday season.
Dec 4, 2025
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NeuMap: A pioneering map of neutrophils that redefines their role in health, infection and inflammation
Neutrophils are the most abundant immune cells in the body and the first to respond to infection or tissue damage. Yet despite their importance, until now very little was known about how they truly function, how they change ...
Dec 3, 2025
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Vitamin C may protect against air pollution, study suggests
Vitamin C may have the potential to protect people against lung disease caused by traffic-related air pollution, bushfires and dust storms, new research finds.
Dec 3, 2025
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Potential therapeutic target for mucosal healing in eosinophilic esophagitis
Researchers at Children's Hospital of Philadelphia (CHOP) identified a potential new therapeutic target for eosinophilic esophagitis (EoE), a chronic allergic inflammatory disease of the esophagus. The findings were published ...
Dec 2, 2025
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Psoriasis rates rise globally, with highest burden in wealthier regions
Researchers in China report that global incidence rates of psoriasis rose slightly from 1990 to 2021 and are projected to continue rising for both men and women through 2050.
