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Inflammatory disorders news
Inflammatory disorders
FDA approves Exdensur for severe asthma
The U.S. Food and Drug Administration has approved Exdensur (depemokimab-ulaa) as an add-on maintenance treatment for severe asthma with an eosinophilic phenotype in adult and pediatric patients aged 12 years and older.
5 hours ago
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Neuroscience
The role of neuroinflammation in progressive multiple sclerosis
Multiple sclerosis (MS) is a disorder that prompts the body's immune system to attack myelin, the protective sheath covering nerve cells in the brain, optic nerve and spinal cord. This can in turn result in vision impairments, ...
Dec 20, 2025
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Eczema injectable drug provides quick itch relief, clinical trial results show
A recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.
Dec 20, 2025
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Blocking a key inflammatory pathway improves liver structure and vascular function in cirrhosis, study finds
Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified an effective strategy to reduce structural liver damage and improve hepatic vascular function in cirrhosis. The study, published in Biomedicine ...
Dec 19, 2025
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Prolonged hydrodistention may provide longer symptom relief in interstitial cystitis
For patients with interstitial cystitis (IC), longer cystoscopic hydrodistention (HD) times may result in improved efficacy and longer symptom relief, according to a study published online Nov. 29 in Neurourology and Urodynamics.
Dec 19, 2025
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Estrogen heightens gut pain sensitivity and may explain IBS gender gap
Women are dramatically more likely than men to suffer from irritable bowel syndrome (IBS), a chronic condition causing abdominal pain, bloating, and digestive discomfort. Now, scientists at UC San Francisco may have discovered ...
Dec 18, 2025
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Key lung immune cells can intensify allergic reactions
Alveolar macrophages are immune cells that live in the tiny air sacs of the lungs. Under normal conditions, these cells act as guardians, keeping the lungs healthy, supporting breathing, and preventing unnecessary immune ...
Dec 18, 2025
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Obesity and inflammation may accelerate lung aging and increase the risk of COPD
A Brazilian study involving nearly 900 participants under the age of 40 reinforces the idea that premature lung aging is linked not only to smoking but also to factors such as obesity and systemic inflammation. These two ...
Dec 17, 2025
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Study finds why asthma drugs help some children but not others
Indiana University School of Medicine researchers are taking a closer look at how young patients respond to biologic treatments for asthma. By analyzing clinical parameters and identifying which children are still likely ...
Dec 17, 2025
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Harmless Klebsiella strain shows powerful protection against gut infections in inflammatory bowel disease model
A team of researchers led by Karina Xavier has uncovered a promising new live biotherapeutic agent that may redefine how the medical field approaches microbiota-based therapies.
Dec 16, 2025
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Little awareness of medical and psychological complexities of steroid cream withdrawal
There is little awareness, particularly among clinicians, of the medical and psychological complexities of "topical steroid withdrawal"—the body's adverse response to the prolonged use of these powerful creams to treat ...
Dec 16, 2025
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A fatal mix-up: How certain gut bacteria drive multiple sclerosis
If gut bacteria are too similar to the protective layer of nerves, they can misdirect the immune system and cause it to attack its own nervous system. This mechanism can accelerate the progression of multiple sclerosis, as ...
Dec 15, 2025
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'Zombie' cells spark inflammation in severe fatty liver disease, researchers find
Mayo Clinic researchers have uncovered how aging "zombie cells" trigger harmful inflammation that accelerates a severe and increasingly common form of fatty liver disease called metabolic dysfunction-associated steatohepatitis ...
Dec 15, 2025
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Persistent inflammation in older adults tied to GDF3 protein signaling
As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis. New research from University of Minnesota researchers reveals how certain immune ...
Dec 15, 2025
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Mpox inflammation traced to AIM2 protein: New insights into immune overdrive
A team of researchers, affiliated with UNIST, has identified a protein sensor that plays a key role in triggering severe inflammatory responses during mpox virus (MPXV) infection. The study reveals that this protein, known ...
Dec 15, 2025
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The role emotions play in inflammatory bowel disease
Many patients with inflammatory bowel disease (IBD) suffer from abdominal pain even between acute inflammatory flare-ups. Altered processing of pain in response to fear may be involved. This is the conclusion of a research ...
Dec 12, 2025
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Psoriasis study shows link between fat metabolism and skin inflammation for first time
A research team led by Erwin F. Wagner from the Medical University of Vienna has discovered a previously unknown molecular mechanism that contributes to the development of psoriasis—and at the same time represents a potential ...
Dec 11, 2025
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New vulnerability of asthma immune cells discovered
Why do certain immune cells remain permanently active in allergic asthma—even in an environment that should actually damage them? A team from the University Hospital Bonn (UKB) and the University of Bonn has discovered ...
Dec 11, 2025
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Allergy risk varies by region: IgE profiles highlight environmental influence and hypoallergenic region
Allergic sensitization follows distinct regional patterns, and molecular IgE profiling can reveal these profiles in detail. An international research team has now demonstrated both phenomena in a population-based study of ...
Dec 11, 2025
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Canadian wildfire smoke worsened pediatric asthma in US Northeast, study shows
New research from the University of Vermont reveals exposure to smoke from Canadian wildfires in the summer of 2023 led to worsening asthma symptoms in children in Vermont and upstate New York.
Dec 11, 2025
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Ticked off: Exploring the rise of tick-induced meat allergy and its connection to cardiovascular disease
Mammalian meat allergy (MMA) is one of the few known food allergies caused by an environmental trigger—a tick bite. In simple terms, MMA results in an allergic reaction to red meat, making it difficult or sometimes even ...
Dec 11, 2025
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Key protein behind necroptotic cell death could drive new treatment strategies
Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a form of inflammatory programmed cell death called necroptosis. Their findings, reported in Nature, ...
Dec 10, 2025
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A subset of patients with depression could benefit from anti-inflammatory treatment, study finds
At any given moment in time, more than 400 million individuals worldwide are battling depression. The antidepressant treatments currently available don't work for many and there is a real need for new, effective treatments.
Dec 10, 2025
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Immune 'switch' identified as a potential target to curb chronic inflammation in cirrhosis
Chronic liver inflammation is one of the most serious complications associated with liver cirrhosis. Researchers from Miguel Hernández University of Elche (UMH) in Spain have identified a molecular mechanism that acts as ...
Dec 10, 2025
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Simple ways to reduce inflammation and protect your heart
If you've ever fought off an infection or iced a sprained knee, you know something about inflammation. But you might not know its importance to heart and brain health.
Dec 9, 2025
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