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Clinical pharmacology news
Common anti-seizure drug prevents Alzheimer's plaques from forming, study shows
While physicians and scientists have long known that Alzheimer's disease involves the buildup of toxic protein fragments in the brain, they have struggled to understand how these harmful fragments are produced. Now, in a ...
5 hours ago
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Single DMT dose treats stress-induced depression more effectively than Prozac in mice
Psychedelics are psychoactive substances that trigger unusual mental states, also referred to as "trips," altering the perceptions, thoughts, and emotions of those taking them and typically inducing hallucinations. Over the ...
11 hours ago
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HPV cancer vaccine slows tumor growth and extends survival in preclinical model
Throughout the past decade, Northwestern University scientists have uncovered a striking principle of vaccine design: Performance depends not only on vaccine components but also on vaccine structure. After proving this concept ...
7 hours ago
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Tiny worm offers clues to combat chemotherapy neurotoxicity
Chemotherapy remains one of the most powerful tools in the fight against cancer, yet it often comes with significant long-term side effects that can dramatically affect patients' quality of life. Among the most debilitating ...
11 hours ago
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Established cancer drug can reactivate immunotherapy
Genetically modified immune cells can offer precious additional time to patients with advanced multiple myeloma. However, these therapies lose their impact as the molecules on cancer cells that immune cells recognize gradually ...
12 hours ago
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Experimental drug may protect the brain against depression and cognitive impairment caused by whole brain radiotherapy
Whole brain radiotherapy (WBRT) saves lives by treating cancer that has spread to the brain, but it also causes long-standing brain damage. Many patients who go through radiation treatment later develop memory problems, thinking ...
4 hours ago
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Triple therapy shown to help with cystic fibrosis in the long term
Cystic fibrosis (CF) is the most common inherited metabolic disease in Europe. More than 8,000 people in Germany are affected. Every year, about 150 to 200 children are born with this incurable disease. It is caused by a ...
3 hours ago
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Discontinuing antidepressants in pregnancy nearly doubles risk of mental health emergencies, finds study
Pregnant patients who stopped taking their antidepressant medication during pregnancy were almost twice as likely to experience a mental health emergency compared with pregnant patients who continued taking their prescription, ...
3 hours ago
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Natural gut-based compound developed to support weight loss safely
A new orally taken, gut-based compound developed by scientists from Nanyang Technological University, Singapore (NTU Singapore), reduces the amount of dietary fat absorbed in the intestines. This differs from most existing ...
4 hours ago
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Investigators study ivermectin's 'ability to kill cancer cells'
The National Cancer Institute, the federal research agency charged with leading the war against the nation's second-largest killer, is studying ivermectin as a potential cancer treatment, according to its top official.
14 hours ago
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Moderna says FDA refuses its application for new mRNA flu vaccine
The U.S. Food and Drug Administration is refusing to consider Moderna's application for a new flu vaccine made with Nobel Prize-winning mRNA technology, the company announced Tuesday.
17 hours ago
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In comparing real-world costs and benefits of fibromyalgia medications, a clear winner emerges
Fibromyalgia is a long-term chronic condition that causes widespread pain in the muscles and soft tissues throughout the body. The illness can affect people of all ages and has a major impact on quality of life, often making ...
Wastewater reveals increase in new synthetic opioids during major New Orleans events
In early 2025, the party-loving city of New Orleans, Louisiana, hosted two major events within the span of a month: Super Bowl LIX and Mardi Gras. And, as with many major events, it appears there was an increase in recreational ...
Feb 10, 2026
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Can a 'love hormone' drug prevent stress anxiety? What rat tests suggest
Researchers at São Paulo State University (UNESP) in Brazil have demonstrated in rats that a synthetic version of oxytocin can prevent anxiety-related behaviors caused by social stress. The study was published in the journal ...
Feb 10, 2026
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Global study marks major treatment advance for tough-to-treat high-risk blood cancer
Results from a new clinical trial led by Wake Forest University School of Medicine and Atrium Health Levine Cancer show that a new therapy could provide significantly better outcomes for patients with high-risk essential ...
Feb 10, 2026
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Why people won't quit a weight loss drug, even when it makes them feel sick
Patients who use semaglutide for weight loss, like Ozempic, are more likely to continue the medication if they perceive it as effective, even when facing unpleasant side effects, according to Rutgers Health researchers. Their ...
Feb 10, 2026
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GLP-1 drugs may protect the heart beyond weight loss, trial results suggest
With the use of GLP-1 medications on the rise, cardiologists are seeing benefits to heart health, and it might not all be related to weight loss alone. GLP-1 medications, including semaglutide, are a class of drugs that act ...
Feb 10, 2026
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FDA to reassess the safety of BHA, a preservative used in popular snack foods
Federal health officials said Tuesday they will reassess the safety of a chemical called BHA used in foods including potato chips, cereals, frozen meals and meat products.
Feb 10, 2026
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Faster blood test could support safer decision-making in drug-related emergencies
New research from King's College London suggests that a rapid blood testing method could deliver reliable results far more quickly than previously thought, potentially supporting faster and more accurate decision-making in ...
Feb 10, 2026
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Men resort to buying underground testosterone to bridge access gap
Some men are resorting to obtaining testosterone replacement therapy (TRT) from underground sources due to significant barriers to accessing the therapy through formal medical channels, according to new Griffith University ...
Feb 10, 2026
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Intravenous tenecteplase found beneficial from 4.5 to 24 hours after non-large vessel occlusion ischemic stroke
For patients with non-large vessel occlusion, acute ischemic stroke and salvageable brain tissue, intravenous tenecteplase administered 4.5 to 24 hours after stroke onset is associated with a higher likelihood of excellent ...
Feb 10, 2026
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A kidney drug may help restore fertility in premature ovarian insufficiency
A common kidney medication could be the key to treating a type of infertility that affects up to 3% of women under 40, according to a study published in Science.
Prolonged use of the drug omeprazole may lead to nutritional deficiencies
A study warns that the prolonged use of proton pump inhibitors (PPIs) can impair nutrient absorption. PPIs are a class of drugs including medications such as omeprazole, pantoprazole, and esomeprazole. They are used to treat ...
Feb 9, 2026
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First of its kind daily HIV treatment shows promising results
Researchers at Queen Mary University of London have led the clinical development of the first non-integrase strand-transfer inhibitor (INSTI) single tablet treatment for HIV, among growing concern for the potential of widespread ...
Feb 9, 2026
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AI model can accelerate antibody drug production
As instigators of immunity, monoclonal antibodies are marvels of modern medicine, lab-made proteins that can treat cancers, autoimmune diseases, and many other conditions. With the market for these therapies forecast to double ...
Feb 9, 2026
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