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Clinical pharmacology news
Dengue fever is a growing problem: Why it's so hard to beat with vaccines
Dengue, a mosquito-borne disease, affects millions of people every year across Asia, Africa and Latin America. And it's expanding geographically as warmer temperatures and urban growth allow mosquito populations to thrive ...
2 hours ago
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FDA-approved fatty liver drug also suppresses liver tumors in mice
A research team from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), in collaboration with the HKU State Key Laboratory of Liver Research, has found ...
10 hours ago
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Soy isoflavone prodrugs target CB1 receptor to protect blood vessels from atherosclerosis
A research team at National Taiwan University found that abnormal blood flow activates CB1 receptors in endothelial cells, promoting vascular inflammation and dysfunction. Soy-derived isoflavone prodrugs that inhibit CB1 ...
11 hours ago
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Hair loss therapeutic agent safe for both men and women, study finds
Using computational modeling, a research team has developed a novel peptide (MLPH) that promotes hair growth without the side effects of existing drugs. This achievement, accomplished through a joint research project led ...
13 hours ago
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Bone pain reduced with pegfilgrastim administration 72 hours after chemo
For patients with breast cancer, administration of pegfilgrastim 72 hours postchemotherapy reduces pegfilgrastim-induced bone pain (PIBP) compared with administration at 24 and 48 hours, according to a study published online ...
11 hours ago
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Self-management of warfarin dose is safe, effective and empowering, clinical trial shows
Warfarin is an oral anticoagulant, commonly known as blood thinner, that is prescribed to help treat the formation of dangerous blood clots that can lead to stroke or heart attacks. Even with newer medications on the market, ...
World's only deuterium-labeled guinea pig helps scientists study metabolism
A Skoltech scientist has raised the world's only isotope-labeled guinea pig. For 156 days, the animal, named Khryun, was given only heavy water to drink. Such water is non-radioactive and has long been used in biomedical ...
Mar 23, 2026
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Lyme disease vaccine shows over 70% efficacy, but phase three misses main goal
An experimental vaccine for Lyme disease is broadly effective, pharmaceutical companies Pfizer and Valneva announced Monday; however, the latter firm's shares fell because the clinical trial did not reach its main goal.
Mar 23, 2026
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FDA approves higher-dose Wegovy to help people lose more weight
A stronger version of the popular weight loss drug Wegovy is on the way after federal regulators signed off on a higher dose. The U.S. Food and Drug Administration (FDA) approved a 7.2-milligram dose of Novo Nordisk's semaglutide, ...
Mar 23, 2026
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As demand for GLP-1 pills and shots surges, healthy habits are still key
Whether they're using weekly shots or daily pills, more Americans than ever are turning to anti-obesity drugs to lose weight and boost health.
Mar 23, 2026
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Nearly 90,000 bottles of children's ibuprofen recalled nationwide
If you have children's ibuprofen at home, you may want to check the label. Nearly 90,000 bottles have been recalled over possible contamination, the U.S. Food and Drug Administration (FDA) said. The recall affects 89,592 ...
Mar 23, 2026
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Discovery might inform new approach to Huntington's disease
Treatments that target a fragment of the mutant protein that causes Huntington's disease might be more effective than treatments—now in clinical trials—that target the whole protein but leave this fragment intact, a new ...
Mar 21, 2026
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Psychedelic drug MDMA could help treat PTSD—but there's a reason it's not widely available
About 11% of Australians will develop post-traumatic stress disorder (PTSD) at some point in their life.
Mar 21, 2026
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Researchers finally report some good news on endometriosis
This year, International Women's Day coincides with Endometriosis Awareness Month. Endometriosis is a common and painful gynecological disease that impacts 14% of women and girls across the world—currently, there is no ...
Mar 21, 2026
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Researchers launch OZ-ABCD tool to curb medication harm in aged care
Researchers at Monash University, together with a multidisciplinary team of health care professionals and medication safety experts, have developed the first national consensus list of medicines with a high risk of harm in ...
Mar 21, 2026
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Weight-loss drug semaglutide does not slow Alzheimer's disease, two clinical trials find
Oral semaglutide (a GLP-1 pill) is not effective at slowing progression in patients with mild Alzheimer's disease, finds the first large Phase III randomized controlled trials on the topic published in The Lancet.
Mar 20, 2026
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Promising active substance against hepatitis E identified
Around 70,000 people die each year from infections with the hepatitis E virus. There is currently neither a vaccine nor a specific drug against this virus. This could change with the identification of bemnifosbuvir as a compound ...
Mar 20, 2026
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India to tackle global obesity with cheap fat-loss jabs
A deluge of weight-loss drugs is set to transform the global fight against obesity as India prepares to unleash low-cost generic versions of injections like Ozempic after a key patent expired Friday.
Mar 20, 2026
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Pythons' feast-and-famine life hints at new weight loss pathway
Pythons don't nibble. They chomp, squeeze, and swallow their prey whole in a meal that can approach 100% of their body weight. But even as they slither stealthily around the forest, months or even a year may pass between ...
Mar 19, 2026
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Psilocybin combined with psychotherapy shows significant efficacy in treatment-resistant depression
There is an urgent need for new and more effective treatments for depression. The results of a recent study show that psilocybin, an active compound found in certain mushrooms, can have a significant antidepressant effect. ...
Mar 19, 2026
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Early clinical results deliver encouraging milestone for malaria drug candidate
Findings from two early clinical studies suggest a new dual-action antimalarial drug candidate is well tolerated in humans. The first-in-class clinical candidate, MK7602, is being developed by WEHI and global biopharmaceutical ...
Mar 19, 2026
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Clot buster may stop promising stroke medicine from working properly
A clotbusting drug commonly used to treat ischemic stroke interacts negatively with a promising anti-inflammatory treatment (anakinra), underscoring the need to test new stroke therapies alongside existing standard care. ...
Mar 19, 2026
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Are psychedelics better than antidepressants? New study says no
Psychedelic-assisted therapy may be no more effective than traditional antidepressants when patients know what drugs they are actually taking, according to a first-of-its kind analysis that compared how well each type of ...
Mar 18, 2026
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Stopping GLP-1 drugs can quickly erase cardiovascular benefits
Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular ...
Mar 18, 2026
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