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Clinical pharmacology news
Self-management of warfarin dose is safe, effective and empowering, clinical trial shows
Warfarin is an oral anticoagulant, commonly known as blood thinner, that is prescribed to help treat the formation of dangerous blood clots that can lead to stroke or heart attacks. Even with newer medications on the market, ...
5 hours ago
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World's only deuterium-labeled guinea pig helps scientists study metabolism
A Skoltech scientist has raised the world's only isotope-labeled guinea pig. For 156 days, the animal, named Khryun, was given only heavy water to drink. Such water is non-radioactive and has long been used in biomedical ...
6 hours ago
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Lyme disease vaccine shows over 70% efficacy, but phase three misses main goal
An experimental vaccine for Lyme disease is broadly effective, pharmaceutical companies Pfizer and Valneva announced Monday; however, the latter firm's shares fell because the clinical trial did not reach its main goal.
7 hours ago
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FDA approves higher-dose Wegovy to help people lose more weight
A stronger version of the popular weight loss drug Wegovy is on the way after federal regulators signed off on a higher dose. The U.S. Food and Drug Administration (FDA) approved a 7.2-milligram dose of Novo Nordisk's semaglutide, ...
7 hours ago
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As demand for GLP-1 pills and shots surges, healthy habits are still key
Whether they're using weekly shots or daily pills, more Americans than ever are turning to anti-obesity drugs to lose weight and boost health.
6 hours ago
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Discovery might inform new approach to Huntington's disease
Treatments that target a fragment of the mutant protein that causes Huntington's disease might be more effective than treatments—now in clinical trials—that target the whole protein but leave this fragment intact, a new ...
Mar 21, 2026
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Psychedelic drug MDMA could help treat PTSD—but there's a reason it's not widely available
About 11% of Australians will develop post-traumatic stress disorder (PTSD) at some point in their life.
Mar 21, 2026
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Researchers finally report some good news on endometriosis
This year, International Women's Day coincides with Endometriosis Awareness Month. Endometriosis is a common and painful gynecological disease that impacts 14% of women and girls across the world—currently, there is no ...
Mar 21, 2026
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Researchers launch OZ-ABCD tool to curb medication harm in aged care
Researchers at Monash University, together with a multidisciplinary team of health care professionals and medication safety experts, have developed the first national consensus list of medicines with a high risk of harm in ...
Mar 21, 2026
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Weight-loss drug semaglutide does not slow Alzheimer's disease, two clinical trials find
Oral semaglutide (a GLP-1 pill) is not effective at slowing progression in patients with mild Alzheimer's disease, finds the first large Phase III randomized controlled trials on the topic published in The Lancet.
Mar 20, 2026
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Promising active substance against hepatitis E identified
Around 70,000 people die each year from infections with the hepatitis E virus. There is currently neither a vaccine nor a specific drug against this virus. This could change with the identification of bemnifosbuvir as a compound ...
Mar 20, 2026
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India to tackle global obesity with cheap fat-loss jabs
A deluge of weight-loss drugs is set to transform the global fight against obesity as India prepares to unleash low-cost generic versions of injections like Ozempic after a key patent expired Friday.
Mar 20, 2026
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Pythons' feast-and-famine life hints at new weight loss pathway
Pythons don't nibble. They chomp, squeeze, and swallow their prey whole in a meal that can approach 100% of their body weight. But even as they slither stealthily around the forest, months or even a year may pass between ...
Mar 19, 2026
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Psilocybin combined with psychotherapy shows significant efficacy in treatment-resistant depression
There is an urgent need for new and more effective treatments for depression. The results of a recent study show that psilocybin, an active compound found in certain mushrooms, can have a significant antidepressant effect. ...
Mar 19, 2026
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Early clinical results deliver encouraging milestone for malaria drug candidate
Findings from two early clinical studies suggest a new dual-action antimalarial drug candidate is well tolerated in humans. The first-in-class clinical candidate, MK7602, is being developed by WEHI and global biopharmaceutical ...
Mar 19, 2026
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Clot buster may stop promising stroke medicine from working properly
A clotbusting drug commonly used to treat ischemic stroke interacts negatively with a promising anti-inflammatory treatment (anakinra), underscoring the need to test new stroke therapies alongside existing standard care. ...
Mar 19, 2026
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Are psychedelics better than antidepressants? New study says no
Psychedelic-assisted therapy may be no more effective than traditional antidepressants when patients know what drugs they are actually taking, according to a first-of-its kind analysis that compared how well each type of ...
Mar 18, 2026
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Stopping GLP-1 drugs can quickly erase cardiovascular benefits
Following a rapid increase in popularity of GLP-1 drugs for diabetes and weight loss, such as semaglutide and tirzepatide, approximately one in eight U.S. adults now take these medications, which also provide cardiovascular ...
Mar 18, 2026
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GLP-1 medications used to treat diabetes and obesity may also help alleviate symptoms of anxiety and depression
GLP-1 medications used to treat diabetes and obesity were associated with a reduced need for hospital care and sickness absence due to psychiatric reasons, a new study shows. The large register-based study was carried out ...
Mar 18, 2026
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Experimental hookworm vaccine shows promising protection in phase 2 human trial
Researchers at the George Washington University School of Medicine and Health Sciences in partnership with Baylor College of Medicine report encouraging results from a phase 2 clinical trial evaluating a candidate vaccine ...
Mar 18, 2026
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FDA-approved compound promotes neuroprotective effects in Parkinson's disease
Northwestern Medicine scientists have discovered that an FDA-approved compound promotes neuroprotective effects in experimental models of Parkinson's disease. The compound, N-acetyl-L-leucine (NALL), simultaneously targets ...
Mar 18, 2026
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What is 'eye stroke' and why has it been linked to weight loss injections?
The phrase "eye stroke" has recently appeared in news reports about a very rare side effect of weight-loss injections. It's not a formal medical diagnosis, but a shorthand used to describe a condition in which reduced blood ...
Mar 18, 2026
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Study of coroners' reports highlights safety concerns linked to fentanyl patch deaths
Fentanyl is a highly potent and fast-acting synthetic opioid used to treat severe pain and is available in several forms, including injections, nasal sprays and skin patches. The study, which is published in the British Journal ...
Mar 18, 2026
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Could an anti-aging therapy worsen myelin loss? Findings raise caution and MS clues
A two-drug combination frequently used in anti-aging research causes brain damage in mice, report University of Connecticut researchers in the Proceedings of the National Academy of Sciences. The findings, titled "Senolytic ...
Mar 17, 2026
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Hidden drug reservoirs in cancer cells could explain treatment resistance
One of oncology's biggest challenges is that the same treatment can work well for some patients but fail completely in others. A study published in Nature Communications, by a multidisciplinary team led by Dr. Louise Fets ...
Mar 17, 2026
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