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Clinical pharmacology news
Indigenous-led project sets new benchmarks for ethical cultural medicine research
Traditional Knowledge has supported health and well-being practices for thousands of years using medicinal plants and cultural medicines. But how can that knowledge be applied appropriately for use in scientific drug discovery?
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Newest medicines work just as well at half dosage for stable psoriasis, new study finds
Three-quarters of people who respond well to the newest types of biologics for psoriasis can safely reduce their dosage, often even by half. These medications then work just as effectively, according to a study led by Radboud ...
12 hours ago
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Global rules could cut costs and speed access to GLP-1 drugs
FDA-approved carbon copies of brand-name drugs with expired patents—over the last 30 years, these generic drugs have saved trillions of dollars for hundreds of millions of people.
18 hours ago
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'We need to act now': Race to develop Ebola vaccine heats up
Several non-profit organizations announced Monday they are ramping up efforts to rapidly develop a vaccine for the rare strain of Ebola driving a deadly outbreak in the Democratic Republic of Congo.
11 hours ago
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Commonly prescribed medication for sleep problems raises alarm bells
Amid growing concern about the widespread off-label use of sedative medications for sleep problems, Flinders University researchers have led a world-first clinical trial examining how a commonly prescribed "sleeping pill" ...
15 hours ago
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Ibuprofen for joint pain: What you really need to know
Millions of people in the UK suffer from joint pain and arthritis. But with long wait times for scans, specialist appointments, physiotherapy, and joint replacement surgery, many people turn to over-the-counter medicines, ...
18 hours ago
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The dangers of legitimizing doping
In Las Vegas May 2026, athletes compete in an international sporting event that explicitly allows them to use performance-enhancing drugs (PEDs). The Enhanced Games openly encourages competitors to use substances banned in ...
16 hours ago
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One-time gene editing treatment lowers 'bad' cholesterol by up to 62%
Patients in London have received a pioneering new gene editing therapy that lowers "bad" cholesterol after a single infusion, as part of a study involving UCL scientists.
May 31, 2026
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Influencers are promoting dangerous peptides on social media, and regulators are struggling to keep up
Once confined to niche bodybuilding forums and hardcore gyms, unproven injectable peptides are now being openly marketed online to the average gym-goer by social media influencers—and regulators struggling to keep up.
May 31, 2026
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One inhibitor, opposite outcome: How a double-target effect could reshape ferroptosis therapies
Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious problems for cells. Surprisingly, the opposite is also true: Cells can become highly resistant ...
May 30, 2026
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Tezepelumab helps severe asthma patients reduce oral steroids over 28 weeks
New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining ...
May 30, 2026
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Cannabidiol significantly reduces chronic pain for those with nerve damage
A new study by researchers at the University of Sydney has shown that taking cannabidiol (CBD) can significantly reduce chronic neuropathic pain in those suffering from it. The findings of the randomized placebo-controlled ...
May 29, 2026
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Why metformin matters beyond diabetes: New target could reshape aging and cancer research
Scientists at Université de Montréal have figured out how metformin—a common drug that's used to treat type-2 diabetes and that may cut the risk of developing cancer and even help humans and other mammals live longer—actually ...
May 29, 2026
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Targeted drug outperforms chemotherapy for patients with hard-to-treat lung cancer
The targeted therapy sunvozertinib was more effective than standard platinum-based chemotherapy as a first-line treatment for patients with advanced non-small cell lung cancer (NSCLC) driven by EGFR exon 20 insertion mutations ...
May 29, 2026
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Simulation-guided search uncovers two promising tuberculosis drug candidates targeting CYP
A research team led by Associate Professor Noriyuki Kurita from the Department of Computer Science and Engineering at Toyohashi University of Technology and by Associate Professor Pornpan Pungpo from Ubon Ratchathani University ...
May 29, 2026
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New antibiotic design could help treat drug-resistant infections
A new way of designing antibiotics could support the discovery of new treatments for drug-resistant infections. It could also help revive antibiotics that have lost effectiveness because bacteria have evolved over time to ...
May 29, 2026
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Rise of dangerous drug adulterant and public health response tracked in New York State
A dangerous sedative called medetomidine has been quietly spreading through New York's illicit drug supply. A new analysis shows how, over several years of careful tracking and coordination, public health agencies in New ...
May 28, 2026
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New study points to possible new treatment for rheumatoid arthritis
There is good news for patients with rheumatoid arthritis. Research from Aarhus University and Aarhus University Hospital may have opened the door to an entirely new way of reducing inflammation in the joints. The study is ...
May 28, 2026
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The Enhanced Games set out to 'transform sport' but the results looked surprisingly ordinary
The Enhanced Games promised a revolution. Athletes on supervised drug regimens, unshackled from the anti-doping rules of the Olympics, were going to show us what the human body was truly capable of. The event was transhumanism ...
May 28, 2026
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African Union's health agency vows Ebola Bundibugyo vaccine by end of 2026
A vaccine against the Bundibugyo strain of the Ebola virus will be ready by the end of the year, the head of Africa Centers for Disease Control and Prevention (Africa CDC) said Thursday.
May 28, 2026
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Why caffeine can sabotage deep sleep even when you still get eight hours
Evening coffee has sparked controversy for years. Some people fall asleep without difficulty, while others toss and turn for half the night. However, a growing body of research suggests the question of whether coffee makes ...
May 27, 2026
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Medical marijuana: Can getting high be good for your health?
Cannabis is a psychoactive drug derived from the Cannabis sativa plant. Users can smoke the dried flowers and leaves as marijuana or make them into an oil or resin.
May 27, 2026
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Machine learning closes research gaps in drug safety during pregnancy, research shows
A report in the Journal of Medical Internet Research shows developments in the evidence gap in drug safety during pregnancy in its News and Perspectives section. In "How Machine Learning Can Help Close Evidence Gaps for Drug ...
May 27, 2026
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KRAS degradation induces rapid lung cancer regression in preclinical mouse models
KRAS is one of the oncogenes most frequently altered in cancer, mutating in approximately one-third of lung adenocarcinomas. For decades, it was considered undruggable, until the recent approval of the first inhibitors against ...
May 27, 2026
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Tirzepatide superior to intensified conventional care for early type 2 diabetes
Tirzepatide is superior to intensified conventional care (ICC) for adults with early type 2 diabetes (T2D) uncontrolled with metformin, according to a study published online May 26 in the Annals of Internal Medicine.
May 27, 2026
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