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Clinical pharmacology news
Biomarker-matched drug combos shrink treatment-resistant melanoma in preclinical models
A new study led by researchers at The University of Texas MD Anderson Cancer Center has identified a way to tailor drug combinations based on specific tumor biology to improve outcomes for treatment-resistant advanced melanoma.
4 hours ago
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Inhaled analgesia is as effective as morphine for early pain relief, study shows
Treating pain while in the field can be very demanding. Researchers have finally identified an effective alternative for providing pain relief during the earliest phase of prehospital care, when establishing intravenous access ...
8 hours ago
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Dementia-causing substance turns into a therapeutic 'switch' with new Alzheimer's drug strategy
A substance that worsens dementia has become a "switch" that initiates treatment. KAIST researchers have developed a new therapeutic approach that uses hydrogen peroxide (H₂O₂), a reactive oxygen species that damages cells ...
10 hours ago
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New drug unlocks elusive immune receptor, opening path toward motor neuron disease treatments
University of Queensland researchers have developed a drug that activates a hard-to-target immune receptor—a breakthrough that could lead to new treatments for neurodegenerative conditions like motor neuron disease (MND).
4 hours ago
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CBD reduces seizures in drug-resistant pediatric epilepsy, study finds
A new study has found cannabidiol (medicinal cannabis) to be a promising treatment for several drug-resistant forms of pediatric epilepsy, offering renewed hope to families.
10 hours ago
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7 things to know about Medicare's new GLP-1 coverage
For decades, it's been against the law for Medicare to pay for weight-loss medication. But that changed on July 1, with the launch of a new program called Bridge. It gives some people over 65, or who have Medicare for other ...
6 hours ago
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Low-cost treatment for multiple sclerosis shown to be as effective as standard therapy
A Norwegian-Swedish clinical trial published in the New England Journal of Medicine demonstrates that rituximab, a low-cost B-cell-depleting therapy, is as effective as ocrelizumab in newly diagnosed relapsing multiple sclerosis ...
11 hours ago
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Trial of potential Ebola treatments begins in DR Congo: WHO
The trial of two potential treatments for the Bundibugyo species of Ebola behind the deadly outbreak in the DR Congo began in the country Thursday, the World Health Organization said.
7 hours ago
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Bofanglutide linked to meaningful reductions in HbA1c in adults with T2DM
For adults with type 2 diabetes mellitus (T2DM), bofanglutide, a glucagon-like peptide-1 receptor agonist, is associated with more meaningful reductions in hemoglobin A1C (HbA1c) levels than semaglutide, according to a study ...
4 hours ago
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Should pregnant women worry about taking Tylenol? 20-year sibling-matched study finds no link to autism or ADHD
Tylenol (also known as acetaminophen or paracetamol) is one of the most widely used over-the-counter options for easing pain and reducing fever, including during pregnancy. More recently, safety concerns around use during ...
Rare muscle disorder mutations reveal a precision medicine strategy
Scientists at the University of California San Diego have uncovered how genetic mutations cause a rare group of inherited neuromuscular disorders and identified promising new strategies to correct them, including a potential ...
Jul 1, 2026
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Bacteria's 'mix-and-match' code could create new cancer-fighting drugs
A team of researchers at the University of Warwick and Monash University has solved a puzzle that has stumped drug developers for decades: how bacteria naturally create multiple versions of powerful cancer therapies. The ...
Jul 1, 2026
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Could creatine help depression? What five clinical trials show so far
Could the same supplement many people take to build muscle also help treat depression?
Jul 1, 2026
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Discovery could help prevent cancer drug resistance before it starts
Cancer cells are quick to develop resistance to anti-tumor drugs. New research by scientists from the University of California, Davis, shows how cancers adapt to evade a class of anti-tumor drugs called BET inhibitors and ...
Jul 1, 2026
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GLP-1 drugs outperform SGLT-2 drugs for patients with Afib and type 2 diabetes
Individuals with atrial fibrillation (Afib), or irregular heart rhythm, are at increased risk of stroke, chronic kidney disease and heart failure. These risks are significantly exacerbated if a type 2 diabetes diagnosis is ...
Jul 1, 2026
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Psychedelics not yet ready for clinical use in ADHD treatment, study finds
In recent years, there has been growing interest among adults with ADHD in the practice of microdosing classic psychedelics such as psilocybin and LSD. The internet is full of personal accounts describing improved concentration, ...
Jul 1, 2026
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UK-US trade deal will mean the NHS has to divert billions from other services to pay more for new medicines
Around £45 billion in NHS funding will be diverted from other NHS care by 2036 to pay more for new medicines under the UK-U.S. trade deal agreed last December unless more funding is made available to cover the additional ...
Jul 1, 2026
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The hidden risks of gray‑market peptides: Why women face greater danger
A wave of unregulated peptides is sweeping the wellness world, sold online with bold promises about muscle gain, anti-aging and fat loss. But concern is growing about side effects, and almost nobody is asking whether these ...
Jul 1, 2026
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Whether children receive opioids after surgery varies by hospital and procedure type
Whether children receive an opioid prescription after surgery varies substantially by procedure type and hospital, according to a new national analysis published in the Journal of the American College of Surgeons. The study ...
Jul 1, 2026
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GLP-1 medications linked to fewer deaths and amputations in people with type 2 diabetes and PAD
According to new, independent research published in the Journal of the American Heart Association, GLP-1 receptor agonist (GLP-1 RA) medications reduce the number of deaths, amputations and hospitalizations among people with ...
Jul 1, 2026
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Acute respiratory distress syndrome patients improve with experimental monoclonal antibody treatment
Doctors have few options for patients who develop a life-threatening lung condition called acute respiratory distress syndrome, or ARDS. A frequent cause of death during the COVID-19 pandemic, ARDS occurs when an inflammatory ...
Jul 1, 2026
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Substantial rise in antinausea medicine use during pregnancy, New Zealand study shows
There has been a fivefold increase in the use of antinausea medicines during Aotearoa New Zealand pregnancies, a University of Otago—Ōtākou Whakaihu Waka-led study has found.
Jul 1, 2026
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FDA scientists warn against expanded peptide access as Kennedy reshapes advisory panel
Federal health scientists are urging caution about expanding access to controversial peptide drugs, even as the U.S. Food and Drug Administration (FDA) reshapes the advisory panel that will consider whether to loosen those ...
Jul 1, 2026
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Billions of doses later: Global review confirms mRNA vaccines are safe, effective and full of promise
A sweeping global review led by researchers at the University of British Columbia has found that mRNA vaccines—now administered billions of times worldwide—are safe and highly effective at preventing infectious diseases like ...
Jun 30, 2026
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Repurposed epilepsy drug could be used to boost vaccine protection among elderly
A drug commonly used to treat epilepsy could be repurposed to significantly boost the response to vaccines in humans, helping protect those for whom the vaccine is less effective, such as older adults or immunocompromised ...
Jun 30, 2026
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