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Clinical pharmacology news
Combination therapy can help global fight against antibiotic resistance
A Monash University-led study has found that an unusual pairing of two commonly used antibiotics can kill and stop the spread of resistance in a highly drug-resistant bacterium, Pseudomonas aeruginosa, which can cause life-threatening ...
11 hours ago
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Nanotech platform combining paclitaxel with siRNA boosts immune response against lung cancer
Researchers at the University of Arizona R. Ken Coit College of Pharmacy have developed a new strategy that helps the immune system recognize and attack lung cancer tumors more effectively. By packaging a chemotherapy drug ...
7 hours ago
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Small-molecule antiviral drug targets ACE2 receptor to block coronaviruses from entering cells
The ongoing evolution of SARS-CoV-2, particularly the rapid emergence of the omicron variant and its sublineages, has weakened the effectiveness of existing vaccines and antiviral drugs, underscoring the potential risk of ...
8 hours ago
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Unfolding stomach capsule could target ulcer-causing bacteria for 48 hours
Between 50% and 100% of people in countries with poor access to clean water are infected with a bacterium called Helicobacter pylori. This bacterium is a leading cause of stomach ulcers, and it can even cause gastric cancer.
15 hours ago
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How 'peacemakers' of the immune system could unlock long-term disease remission
"Peacemaker" immune cells could help treat diseases ranging from type 1 diabetes to neurodegeneration by restoring immune tolerance, according to a new paper in Frontiers in Science.
19 hours ago
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New oral heart failure drug appears to be safe and well tolerated in 58-patient early clinical trial
An early clinical study shows that a new oral drug is safe and well tolerated in patients with chronic heart failure. The study, led by researchers at Karolinska Institutet, has been published in The Lancet.
10 hours ago
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Eliminating cancer cells that survive KRAS inhibition: A potential way to prevent relapse
Our cells rely on tightly regulated signaling pathways to control when they grow, divide and survive. When these regulatory systems are disrupted, cells can acquire the ability to grow uncontrollably and become cancerous. ...
15 hours ago
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Why ibuprofen is better than paracetamol for period pain
For something that affects millions every month, period pain remains surprisingly poorly treated.
9 hours ago
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GLP-1 weight-loss boom linked to surge in poison control calls
As the use of GLP-1 medications for weight loss surges, so do calls to U.S. poison control centers, according to a new study.
9 hours ago
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Will GLP-1s lead to fewer prescriptions for older adults?
As people age, they often develop chronic conditions, many of which need to be managed with multiple prescription medications. While medications are important for disease management, polypharmacy poses an increased risk for ...
13 hours ago
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Language models read doctors' notes to reveal why patients discontinue medication
Researchers at the University of Tartu showed that large language models can identify with high accuracy why patients stop using antidiabetic medications or statins based on doctors' electronic clinical notes. The study opens ...
12 hours ago
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Using AI to tackle global superbug crisis
The development of new antibiotics could be sped up thanks to a new tool that tests the reliability of AI. University of Queensland researchers designed a framework to address the global threat of antimicrobial resistance, ...
13 hours ago
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New COPD injection targets proteins in body to reduce inflammation
For the first time, patients have received a new injection for chronic obstructive pulmonary disease (COPD), thanks to research by King's College London.
14 hours ago
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New oral GLP-1 drug delivers up to 12% weight loss in 36 weeks
A new strategy for delivering GLP-1 drugs to patients with obesity or who were overweight resulted in up to a 12% reduction in body weight after 36 weeks, according to a randomized phase II clinical trial published in Nature ...
Jun 24, 2026
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How high cholesterol dismantles the liver's defenses—and how a new drug could combat it
Cholesterol-related heart disease remains the leading cause of death worldwide, and while doctors have more tools than ever to treat it, many patients still can't achieve safe cholesterol levels or can't tolerate the side ...
Jun 24, 2026
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Trials of two Ebola treatments to start in DRC next week: WHO
Trials of two separate potential treatments to fight the deadly Ebola outbreak in the Democratic Republic of Congo are expected to begin next week, the World Health Organization said Wednesday.
Jun 24, 2026
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Hidden medication risks for older Australians in aged care transition revealed
New research has shown concerning patterns of medication use among older Australians transitioning into residential aged care that may increase the risk of medication-related harm, highlighting opportunities to improve medication ...
Jun 24, 2026
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Foundational research points to new therapeutic strategies for an emerging cancer drug
Pancreatic cancer is one of the deadliest cancers and the third-leading cause of cancer-related death in the United States. While scientists continue searching for new therapies, advances can also come from understanding ...
Jun 23, 2026
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Lab-engineered proteins: A promising treatment for liver disease
The research group led by CIC biomaGUNE's Ikerbasque Research Professor Aitziber L. Cortajarena has developed an innovative anti-fibrotic and anti-tumor treatment by binding a synthetic protein to gold nanoclusters (small ...
Jun 23, 2026
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FDA approves oral Utebzi antibiotic for complicated urinary tract infections
The U.S. Food and Drug Administration has approved GSK's Utebzi (tebipenem pivoxil), an oral antibiotic, for the treatment of complicated urinary tract infections (cUTIs).
Jun 23, 2026
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Testosterone therapy labels and limits may change under FDA proposal
The U.S. Food and Drug Administration (FDA) is asking drugmakers to update the prescribing information on testosterone replacement therapy products to reflect newer clinical evidence.
Jun 23, 2026
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Promising single-dose malaria treatment advances toward pan-African clinical trial
Researchers at the German Center for Infection Research (DZIF) have developed a promising single-dose malaria treatment that could help address growing drug resistance and simplify treatment for patients. The four-drug combination ...
Jun 23, 2026
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Expert explains how two pieces of federal action may impact marijuana research, sales, transport, and consumption
As the U.S. Drug Enforcement Administration (DEA) gears up for its administrative hearing on the fate of federal marijuana legalization, UNLV Cannabis Policy Institute (CPI) director Riana Durrett offers a rundown on decades ...
Jun 23, 2026
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Erucamide molecule strengthens the eye's response to damage in retinal disease
Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye. Although scientists know some of the structural changes that ensue as this ...
Jun 22, 2026
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Weight‑loss drugs like Ozempic could work for addiction too—and we finally know how
For many people, the thought of a tasty burger or a cold pint of beer conjures a vivid mental image and drives behavior. This link between thinking and doing serves a clear function—it motivates us to get the necessities ...
Jun 22, 2026
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