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Clinical pharmacology news
Berberine as a natural Ozempic? An analysis of a popular myth
In recent years, berberine has increasingly appeared in the public sphere as a "natural way" to improve metabolism. In social media, it is sometimes compared to incretin drugs and even referred to as "plant-based Ozempic." ...
2 hours ago
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Scientists find a new therapeutic target present on up to half of all tumors
For five decades, scientists have known about a notorious cancer-causing enzyme called SRC. But they always assumed it only appeared on the inside of cells, where it sent signals that fueled tumor growth and stayed hidden ...
21 hours ago
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Federal drug price reforms are improving medication adherence, new study finds
More than 1 in 4 U.S. adults struggle to afford their prescription medications. Those who can't are left with grim choices—such as skipping doses, cutting pills in half, or abandoning prescriptions entirely—that can come ...
22 hours ago
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Romiplostim prevents serious side effect of chemotherapy in phase 3 trial
Results from a global phase 3 clinical trial led by investigators at Mass General Brigham show that the medication romiplostim can effectively prevent chemotherapy from destroying platelet-producing bone marrow cells, a common ...
17 hours ago
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FDA provides fast track designation to nipocalimab for systemic lupus erythematosus
Johnson & Johnson's nipocalimab has been granted U.S. Food and Drug Administration Fast Track designation as a potential treatment for adults with systemic lupus erythematosus (SLE).
16 hours ago
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Evaluating the effects of hypnotics for insomnia in obstructive sleep apnea
Obstructive sleep apnea (OSA) is a common sleep disorder characterized by oxygen desaturation due to repeated airway collapse during sleep. This leads to oxygen desaturation or awakening from sleep. It is often linked to ...
17 hours ago
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Trial finds vitamin D supplements don't reduce COVID severity but could reduce long COVID risk
In a large, randomized trial, researchers at Mass General Brigham found that high-dose vitamin D3 did not reduce COVID-19 infection severity, but may impact long COVID outcomes. Results of the study are published in The Journal ...
Mar 12, 2026
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Large-scale study challenges link between acetaminophen use during pregnancy and autism risk in children
A team of Taiwanese researchers have used a nationwide, population-based cohort to examine whether taking acetaminophen during pregnancy might be linked to a higher likelihood of attention-deficit/hyperactivity disorder ...
Active ingredient of Viagra can help treat rare genetic disease
Sildenafil—an active ingredient also marketed under the name of Viagra—improves symptoms in patients with Leigh syndrome. This has now been reported in the journal Cell by researchers at Charité—Universitätsmedizin ...
Mar 11, 2026
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New malaria vaccine shows promise in preclinical trials
Malaria is caused by a parasite that is spread to humans by infected mosquitoes. In 2024, almost 282 million people worldwide were infected and 610,000 died, according to the World Health Organization. Malaria is a leading ...
Mar 11, 2026
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Claims data study ties epilepsy drugs in pregnancy to developmental risks
Findings published by The BMJ reinforce previous research linking use of the antiseizure drug valproate during pregnancy to neurodevelopmental disorders such as ADHD and autism in children, and indicate no substantial risk ...
Mar 11, 2026
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Dengue vaccine remains 80.5% effective against severe cases after five years
In a phase 3 clinical trial, the tetravalent dengue vaccine, developed by the Butantan Institute in São Paulo, Brazil, was 80.5% effective against severe dengue cases with warning signs over a five-year period. The results ...
Mar 11, 2026
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Safer blood clot treatment: Apixaban beats rivaroxaban in head-to-head comparison
The first clinical trial to compare two commonly used drugs head-to-head for venous thrombosis treatment has found a clear winner: while both drugs work well to prevent recurrent blood clots, apixaban is safer than rivaroxaban, ...
Mar 11, 2026
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Study finds ALS drug hope via AI and veteran records
A Lawrence Livermore National Laboratory (LLNL)-led team of scientists and computational engineers using one of the largest electronic health record datasets ever assembled for ALS has identified several existing medications ...
Mar 11, 2026
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Study uncovers a new mechanism explaining how chemicals affect sex hormones
Researchers at the University of Oulu have identified a previously unknown mechanism in humans that may explain why certain medicines and environmental chemicals disrupt the balance of sex hormones. The finding deepens scientific ...
Mar 11, 2026
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Many older adults develop cardiovascular conditions that affect anti-amyloid treatment
A new study finds that a significant portion of older adults with mild cognitive impairment or dementia develop new cardiovascular diagnoses each year that may require treatment with anticoagulants or thrombolytics—medications ...
Mar 11, 2026
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Medicinal cannabis eases endometriosis, pelvic pain
Medicinal cannabis could provide a new treatment option for those with endometriosis, with a study led by the University of Otago, Wellington showing it reduced pain, improved sleep and lowered anxiety. The study, led by ...
Mar 11, 2026
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FDA approves Sotyktu for adults with active psoriatic arthritis
The U.S. Food and Drug Administration has approved Sotyktu (deucravacitinib) for the treatment of adults with active psoriatic arthritis.
Mar 11, 2026
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Deep learning model enables accurate and scalable drug-drug interaction prediction
Managing complex medical conditions often requires the simultaneous use of multiple different drugs, referred to as polypharmacy. While necessary, this significantly increases the risk of drug-drug interactions (DDIs), which ...
Mar 11, 2026
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Nanohydrogels steer cancer drugs to tumors, aiming to spare healthy tissue
Exhaustion creeps in. Appetite vanishes. Hair thins. The person in the mirror looks gaunt. It's the paradox of cancer treatment: The same drugs meant to save a life can also wear the body down. Nick Housley, assistant professor ...
Mar 10, 2026
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Wegovy may have highest 'eye stroke' and sight loss risk among semaglutide GLP-1 agonists
Wegovy, a GLP-1 agonist for weight loss, may carry the highest risk of "eye stroke" (ischemic optic neuropathy) and sudden sight loss of the semaglutide drugs, finds an analysis of unintended side effect reports published ...
Mar 10, 2026
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GLP-1 medication changes may support long-term weight management
Patients without diabetes who switched GLP-1 receptor agonist (GLP-1RA) drugs for overweight or obesity were more likely to stick with their treatment longer than those who didn't switch, according to a new study by UT Southwestern ...
Mar 10, 2026
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Experimental vaccine could help turn the tide on America's opioid epidemic
Virginia Tech researchers are advancing a new generation of vaccines designed to block opioids from reaching the brain and triggering their addictive effects, work that could help prevent overdose deaths that now exceed 100,000 ...
Mar 10, 2026
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Approved IV drug reduces lupus symptoms, clinical trial finds
An already-approved IV drug significantly reduces the symptoms of lupus, a new clinical trial showed. More than three-quarters of lupus patients taking obinutuzumab (Gazvya) had a significant improvement in their symptoms ...
Mar 10, 2026
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Does ginkgo help memory? New review finds limited gains, mainly in dementia
An updated systematic review of dozens of studies finds that Ginkgo biloba may offer modest short-term improvements for people with dementia, but shows little to no benefit for individuals with subjective memory complaints, ...
Mar 10, 2026
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