Last update:
Clinical pharmacology news
Single saRNA shot helps with healing after a heart attack
For people who have survived a heart attack, the notion of one shot in the arm to help the heart heal, for weeks after, may seem far-fetched. But thanks to a team of researchers, including a Texas A&M University professor, ...
8 hours ago
0
0
Trial suggests GLP-1 combo therapy cuts fat while preserving muscle in obesity
A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also preserving lean mass, ...
10 hours ago
0
1
Combination therapy reduces effects of 'zombie cells' in diabetic kidney disease, research finds
Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells—also known as "zombie cells"—in diabetic kidney disease. In eBioMedicine, ...
12 hours ago
0
0
Cannabis compounds show promise in fighting fatty liver disease
Researchers have discovered that non-psychoactive cannabis compounds, CBD and CBG, can significantly reduce liver fat and improve metabolic health. The study reveals that these compounds work by creating a backup energy reserve ...
9 hours ago
0
1
Testosterone therapy could mean trouble for knee replacement patients, study warns
Testosterone therapy is booming in the U.S., but it might bring higher risks for people undergoing knee replacement surgery, a new study says.
7 hours ago
0
0
What to know about how GLP-1 medications might fight addiction
The blockbuster GLP-1 drugs that have reshaped the treatment of diabetes and obesity may help prevent multiple substance use disorders—and reduce the tragic outcomes they cause, a large new study finds.
22 hours ago
0
0
Dangerous health risks exposed in illicit steroid research program
Almost 90% of illegal steroids contain unexpected, incorrect or dangerous substances, a Queensland drug testing study has found. ROIDCheck—a project led by University of Queensland researchers—tested the purity of image ...
14 hours ago
0
0
GLP‑1 drugs may fight addiction across every major substance, according to a study of 600,000 people
A patient of mine, a veteran who had tried to quit smoking for over a decade, told me that after he started a GLP-1 drug for his diabetes, he lost interest in cigarettes. He didn't use a patch. He didn't set a quit date. ...
16 hours ago
0
0
GLP‑1 drugs like Ozempic may lower the risk of addiction: New study
A class of medications best known for treating diabetes and obesity may also reduce the risk of addiction—and help people who already have one, a new study shows.
16 hours ago
0
0
GLP-1 medications get at the heart of addiction, study finds
Researchers at Washington University School of Medicine in St. Louis have shown in a new study that GLP-1 medications may be effective at treating and preventing substance-use disorders across all major addictive substances ...
Mar 4, 2026
0
1
Psychedelics may aid PTSD recovery by repairing brain myelin, study finds
Post-traumatic stress disorder (PTSD) is not only characterized by strongly encoded traumatic memories, but also by disrupted coordination across brain networks. New research shows that treatment with psychedelic drugs triggers ...
Mar 4, 2026
0
0
First gene regulation clinical trials for epilepsy show promising results
A Phase I/IIa clinical trials co-led by Linda Laux, MD, from Ann & Robert H. Lurie Children's Hospital of Chicago, show that the first gene regulation treatment for epilepsy is safe and well tolerated by patients with Dravet ...
Mar 4, 2026
0
0
Common anticholinergic medicines may raise cardiovascular risk, large study suggests
People who use drugs with anticholinergic effects, including certain antidepressants, drugs for urinary incontinence and common antihistamines, are at higher risk of developing cardiovascular disease, according to a new study ...
Mar 4, 2026
0
0
No more weekly injections? How lettuce cells could deliver GLP-1 pills
Research led by Penn Dental's Henry Daniell investigates the use of a lettuce-based, plant-encapsulated delivery platform as a new oral delivery of two GLP-1 drugs previously approved by the FDA in injectable form.
Mar 4, 2026
0
2
GLP-1 weight-loss drugs comparably effective across age, race and starting weight
Popular GLP-1 receptor agonist drugs for weight loss, also known as GLP-1 RAs, appear to be similarly effective among patients of different ages, races, and starting weights, with women benefiting somewhat more than men, ...
Mar 4, 2026
0
0
GLP-1 drugs may cut risk of major heart complications after heart attack
Weight-loss (GLP-1 mimicking) drugs may help prevent further tissue damage following a heart attack, significantly reducing the risk of further life-threatening complications that affect up to half of all patients, according ...
Mar 3, 2026
0
1
Targeted dual antibiotics can cut deaths in high-risk S. aureus bacteremia
A study led by researchers from the Infectious Diseases Service of the Bellvitge University Hospital (HUB), the Bellvitge Biomedical Research Institute (IDIBELL) and the University of Barcelona (UB) shows for the first time ...
Mar 3, 2026
0
0
Diabetes and liver medications failed to treat long COVID
The search for long COVID treatments continues, as a randomized clinical trial found that a two-week course of metformin or ursodeoxycholic acid (UDCA) did not meaningfully improve recovery from symptoms, despite earlier ...
Mar 3, 2026
0
0
Targeting the untargetable cancer—rezatapopt, an oral p53 reactivator
Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator designed for tumors with TP53 Y220C, and observed antitumor activity across multiple solid tumor types ...
Growth hormone receptor could serve as possible target for improving lung cancer treatment
Researchers at Ohio University have discovered what may be a new way to fight lung cancer that is resistant to other treatments. The study, published in the International Journal of Molecular Science and led by Goll-Ohio ...
Mar 2, 2026
0
0
New drug could boost efforts to wipe out sleeping sickness
A new treatment for sleeping sickness could make it much easier to treat and possibly eliminate the deadly disease.
Mar 2, 2026
0
0
Statins, diuretics, and other common heart drugs do not worsen survival in multiple myeloma, scientists report
Commonly prescribed cardiovascular medications—such as statins, diuretics, and blood pressure drugs—appear to have little or no negative impact on survival among people living with multiple myeloma, according to new international ...
Mar 2, 2026
0
0
International mpox trial finds no clinical benefit from tecovirimat
An international, randomized, double-blind, placebo-controlled Phase III study—the largest of its kind for mpox—found that tecovirimat did not improve clinical outcomes for adults with clade II mpox compared with placebo, ...
Mar 2, 2026
0
0
Single dose of non-prescribed Adderall raises blood pressure and heart rate in healthy young adults, finds study
A Mayo Clinic study found that a single 25 mg dose of a combination of amphetamine-dextroamphetamine salts (Adderall) can have measurable cardiovascular effects in healthy young adults. The study aimed to better understand ...
Mar 2, 2026
0
0
FDA to offer cash bonuses for faster drug reviews
The U.S. Food and Drug Administration's (FDA) chief says the agency will begin offering bonuses to drug reviewers who complete their work ahead of schedule.
Mar 2, 2026
0
0