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Clinical pharmacology news
Standard-dose antibiotic is the 'preferred choice' of treatment for uncomplicated acute sinusitis
Acute sinusitis leads to more antibiotic prescriptions for U.S. adults than any other condition, but there is no consensus on which antibiotic is preferred for uncomplicated cases. In a retrospective, nationwide study of ...
2 hours ago
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Blood pressure drug effective for treating antibiotic-resistant bacteria, study finds
Infections from antibiotic-resistant bacteria are difficult to treat and are responsible for over 2.8 million infections and more than 35,000 deaths in the U.S. each year. A new study in Nature Communications reports that ...
20 hours ago
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Skin-deep microneedle sensor tracks drug clearance and reveals early kidney and liver dysfunction
Wearable technologies are starting to reshape how people manage health. Continuous glucose monitors that measure blood sugar levels in diabetes patients have already shown the power of tracking an important molecule in real ...
19 hours ago
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Will retatrutide help me lose weight or look 'shredded?'
Injectable peptides are generating a lot of buzz online.
13 hours ago
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Cannabis sales and use are high in Michigan—but federal law means research lags behind
Have you been to a licensed cannabis dispensary lately? My team and I often visit them in the Greater Lansing area to invite cannabis users to participate in our studies. As soon as we walk in, we are met with a dazzling ...
14 hours ago
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Weight loss research questions need for GLP-1 drugs
A new approach to weight loss research is challenging one of the biggest assumptions behind popular weight loss drugs: Are GLP-1s actually needed to achieve weight loss?
20 hours ago
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FDA to review whether to allow more access to certain peptides
The U.S. Food and Drug Administration (FDA) will soon review whether certain peptides should be allowed in customized medications made by compounding pharmacies.
20 hours ago
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A major pregnancy scare collapses: Tylenol shows no autism risk in more than 1.5 million children
Acetaminophen, which also goes by names like paracetamol or Tylenol, is a common over-the-counter pain reliever and fever reducer. It is often prescribed during pregnancy to help with mild to moderate pain. Recently, there ...
A black licorice compound slashes gut inflammation and cell death in IBD models and animals
A new study published in Stem Cell Reports demonstrates how a human stem cell-derived model of the intestine can be used to identify potential therapies for inflammatory bowel disease (IBD), highlighting glycyrrhizin as a ...
Apr 16, 2026
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First-of-its-kind drug aims to protect the heart while increasing effectiveness of cancer treatments
A team of University of Alberta researchers has developed a cardio-oncology drug that protects the heart from chemotherapy damage while enhancing the effectiveness of cancer treatments against tumor growth and spread. In ...
Apr 16, 2026
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Adding opioids or benzodiazepines to gabapentinoids boosts drug poisoning risk, analysis shows
People who take gabapentinoids, a medication prescribed increasingly frequently worldwide, particularly for chronic pain, face a much greater risk of drug poisoning if they are also taking another medication, finds a new ...
Apr 16, 2026
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GLP-1 in joint fluid may let weight-loss drugs target arthritis directly
Arthritis includes a range of conditions that affect the joints, from inflammatory diseases such as rheumatoid arthritis and psoriatic arthritis to more common conditions like osteoarthritis. Many people experience pain, ...
Apr 16, 2026
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Much-hyped Alzheimer's drugs removed amyloid yet brought no meaningful gains over 18 months
Drugs once hailed as a breakthrough in the fight against Alzheimer's disease do not meaningfully help patients, a major review found Thursday, however some experts criticized the research.
Apr 16, 2026
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One lot of Xanax recalled nationwide over quality issue, FDA says
A widely used anxiety medication is being pulled from shelves due to "failed dissolution specifications," the U.S. Food and Drug Administration (FDA) said.
Apr 16, 2026
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New anti-clotting medication lowers risk of stroke without added bleeding
A large international study has found that asundexian, an investigational anti-clotting medication, reduces the risk of a stroke in people who recently experienced a stroke or transient ischemic attack (TIA) caused by a clot ...
Apr 15, 2026
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Off-label cancer drugs deliver durable benefit for some patients in large trial
The largest published prospective evaluation of off-label targeted cancer therapies has shown that more patients could benefit from existing drugs. After including over 1,600 patients in the Dutch multicenter DRUP trial, ...
Apr 15, 2026
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For women with primary progressive MS, could bestselling drug be doing more harm than good?
The US Food and Drug Administration (FDA) is reviewing a petition to revoke the approval of Roche's top-selling drug ocrelizumab (Ocrevus) for treating primary progressive multiple sclerosis (PPMS)—a form of MS thought to ...
Apr 15, 2026
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Why psychedelic mental health trials may be less reliable than they appear
Drug trials generally involve comparing a treatment with a nonactive, placebo version, an approach called "blinding" because patients must be "blind" as to which they've received for the trial to work. Canadian researchers ...
Apr 15, 2026
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Anti-amyloid Alzheimer's drugs show no clinically meaningful effect
Drugs that target amyloid beta proteins in the brain likely have no clinically meaningful positive effects, while increasing the risk of bleeding and swelling in the brain, a new review in the Cochrane Database of Systematic ...
Apr 15, 2026
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New weight loss pill gets approval, but FDA seeks more safety data
The U.S. Food and Drug Administration (FDA) has told Eli Lilly to study possible heart, liver and other risks tied to its new obesity drug Foundayo, according to an approval letter released Tuesday.
Apr 15, 2026
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Australia's 60-day prescriptions are saving millions; why aren't more patients getting them?
A landmark government policy designed to slash the cost of medicines for millions of Australians is falling well short of its potential because GPs and pharmacists have been slow to adopt it, new research has found. The study, ...
Apr 15, 2026
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New research shows a free online tool could improve opioid safety for millions of Australians
New Monash University research has found that a free, interactive online tool can help people taking prescription opioids for pain to better understand their risks and adopt safer behaviors, more than doubling requests for ...
Apr 15, 2026
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Ads for GLP‑1 drugs are flooding the internet. Here's how to know if it's safe to buy them online
If you watched the Super Bowl in 2026, you likely saw Serena Williams share her weight loss journey on GLP-1 medications in a commercial.
Apr 15, 2026
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New drug doubles 1-year survival in pancreatic cancer trial
Pancreatic cancer is one of the deadliest cancers and among the hardest to treat, with most patients surviving less than a year after diagnosis. But a new drug developed at Northwestern University may soon help patients live ...
Apr 14, 2026
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GLP-1 medicine improves liver health independent of weight loss, study finds
Researchers at Toronto's Sinai Health have found that semaglutide—the active ingredient in popular weight loss drugs that mimic the gut hormone GLP-1—acts directly on a subset of liver cells to improve organ function and ...
Apr 14, 2026
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