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Medications news
Medications
Emergency departments fall short on delivering timely treatment for sickle cell pain, study finds
A new study finds that only one in three patients visiting emergency departments (EDs) for severe pain associated with sickle cell disease received appropriate opioid-based pain-relieving medications within the first hour ...
9 hours ago
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Medications
Study shows no clear evidence of harm from hydroxyurea use during pregnancy
Taking the sickle cell drug hydroxyurea during or shortly before pregnancy does not appear to cause specific issues in newborns, according to the first prospective study of pregnancies involving hydroxyurea exposure. The ...
9 hours ago
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Study finds cystic fibrosis drug allows patients to safely scale back lung therapies
A new multi-site study led by researchers at CU Anschutz shows that people with cystic fibrosis (CF) who start the triple-drug therapy elexacaftor/tezacaftor/ivacaftor (ETI) can safely reduce many of their daily lung treatments ...
Dec 5, 2025
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Innovative drug delivery mechanism triggered by cooling could provide targeted pain relief
Leon Bellan, associate professor of mechanical and biomedical engineering at Vanderbilt, and his team have developed a novel cooling-triggered device that could allow patients to safely and conveniently receive drugs for ...
Dec 5, 2025
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GLP-1RAs shown to reduce risk of cardiovascular death
Glucagon-like peptide-1 receptor agonists (GLP-1RAs) such as semaglutide, liraglutide, and tirzepatide are widely prescribed both for Type 2 diabetes and weight loss. These drugs also have shown promise in clinical trials ...
Dec 5, 2025
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New UK guideline for clopidogrel recommends pharmacogenetic testing for all patients before prescription
The UK Center of Excellence in Regulatory Science and Innovation in Pharmacogenomics (UK CERSI-PGx), led by the University of Liverpool, has published its first clinical guideline focused on the use of the antiplatelet medication ...
Dec 4, 2025
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Experimental drug repairs DNA damage caused by common diseases
Cedars-Sinai scientists have developed an experimental drug that repairs DNA and serves as a prototype for a new class of medications that fix tissue damage caused by heart attack, inflammatory disease or other conditions.
Dec 3, 2025
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Pegcetacoplan—the 'closest thing to a cure' for rare, severe kidney disease
A rare and life-threatening kidney disease in children finally has an effective therapy, thanks in large part to pioneering research and clinical leadership from University of Iowa Health Care Stead Family Children's Hospital.
Dec 3, 2025
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Consumers pay when drugmakers delay, finds study of over-the-counter drug exclusivity rules
Policies designed to encourage drugmakers to introduce over-the-counter (OTC) versions of previously prescription-only medications may in fact harm consumers, shows a new study co-authored by a University of Massachusetts ...
Dec 3, 2025
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Long-term antidepressant use surges in Australia, sparking warnings of overprescribing
Long-term antidepressant use in Australia has risen steadily over the past decade, with the largest increase seen in young people aged 10–24, where rates have more than doubled.
Dec 3, 2025
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Recent changes to EU chemicals legislation are rarely reflected in the EU pharmaceutical sector
Several changes have been made to EU chemicals policy and legislation with the aim of making society greener. These changes may affect the pharmaceutical sector in many ways, but they are rarely reflected in pharmaceutical ...
Dec 3, 2025
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Pain med side effects may be masquerading as heart failure
Clinicians may fail to recognize common side effects of drugs like gabapentin—which are frequently prescribed for nerve pain—leading them to prescribe unnecessary medications that cause yet more side effects. This phenomenon, ...
Dec 2, 2025
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Omomyc enhances PARP inhibitor effects and overcomes resistance in breast cancer models
Findings from a preclinical study demonstrate that Omomyc—the only direct MYC inhibitor to have successfully completed a phase I clinical trial—causes DNA damage in cancer cells which is synergistically enhanced in combination ...
Dec 2, 2025
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How anti-epilepsy drugs alter a key brain protein structure
A multi-institute team led by St. Jude Children's Research Hospital and UT Southwestern Medical Center investigators established for the first time how certain drugs used to treat epilepsy affect their target.
Dec 2, 2025
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WHO issues first guidance on using GLP-1 drugs to treat obesity
The World Health Organization (WHO) released its first-ever guideline on using GLP-1 medications to treat obesity.
Dec 2, 2025
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Common water pill may help HIV medicines work faster and reduce inflammation, early study suggests
An FDA‑approved medication called spironolactone, often prescribed for heart and blood pressure conditions, may be a useful add‑on to the standard HIV treatment, according to new research from the Valente lab at The Herbert ...
Dec 2, 2025
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Study finds people on colchicine need less joint replacement
Gout is the most common form of inflammatory arthritis, with a worldwide prevalence of approximately 4%. The accumulation of monosodium urate crystals in gout leads to the clinical manifestations of the disease and, if left ...
Dec 2, 2025
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During blood pressure treatment, doctors recommend the use of sun protection
Some blood pressure medications can make the skin extra prone to sunburn. A registry study from Lund University in Sweden shows a possible increased risk of basal cell carcinoma with certain blood pressure medications. The ...
Dec 2, 2025
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Taking a drug like Ozempic? What you need to know about risks of suicidal thoughts and contraception failure
The rise of GLP-1 drugs such as Ozempic and Mounjaro has been nothing short of meteoric. Originally developed to treat diabetes, these drugs are now widely used for weight loss and have become household names.
Dec 2, 2025
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Illicit diazepam tablets show wide strength variation
A study from King's, in collaboration with TICTAC Communications and Nanalysis, tested seized tablets containing the sedative diazepam and found considerable variation in strength and content, highlighting the dangers of ...
Dec 2, 2025
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Drug that costs as little as 50 cents per day could save hospitals thousands
A study led by McMaster University researchers shows that a widely available and inexpensive medication not only prevents potentially serious stomach bleeding in critically ill patients, but also saves hospitals thousands ...
Dec 1, 2025
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Telemedicine can dramatically improve coverage of HIV prevention medication
A new study led by researchers at Emory University's Rollins School of Public Health, published Monday by JAMA Network Open, estimates that nearly 20% of U.S. residents who use pre-exposure prophylaxis (PrEP) for HIV prevention—or ...
Dec 1, 2025
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WHO recommends Ozempic-style weight loss drugs for obesity
Obesity affects more than 1 billion people worldwide and is recognized by the World Health Organization as a chronic, relapsing disease associated with substantial morbidity, mortality, and economic burden.
Dec 1, 2025
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Corticosteroid use does not appear to increase infectious complications in non-COVID-19 pneumonia
A systematic review and meta-analysis evaluated the association between corticosteroid therapy, mortality, and infectious complications in adults with severe non-COVID-19 pneumonia or acute respiratory distress syndrome (ARDS). ...
Dec 1, 2025
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US-approved drug to improve quality of life for people with rare condition familial chylomicronemia syndrome
For the first time, a drug to treat adult patients with familial chylomicronemia syndrome (FCS), a severe and rare condition that leads to extremely high levels of blood fats called triglycerides, has been approved by the ...
Nov 28, 2025
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