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Clinical pharmacology news
Which medicines can most affect driving? New tool estimates risk
Researchers from the SABIEN group at the ITACA Institute of the Universitat Politècnica de València (UPV), in collaboration with several partner institutions, have developed a new tool to estimate the risk of using medicines ...
9 minutes ago
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Cancer fatigue may ease within weeks as common stimulant shows benefit
A new meta-analysis in Journal of the National Comprehensive Cancer Network provides updated evidence that methylphenidate-type psychostimulants—a class of medication that increases dopamine and norepinephrine availability ...
2 hours ago
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Peppermint oil can lower blood pressure, clinical trial finds
Daily doses of peppermint oil have been proved to lower blood pressure for patients with mildly high readings, new research has found. A team of University of Lancashire academics discovered a daily intake of 100 microliters ...
20 hours ago
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15-year quest yields malaria compound that hits parasite at all major stages
A Portland State University-led research team has developed a novel chemical compound that shows promise for the treatment and prevention of malaria, one of the world's deadliest diseases. Malaria, a mosquito-borne infectious ...
21 hours ago
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How one drug could lower dangerous bleeding in high-risk cesarean births
Giving tranexamic acid to women with placenta previa (when the placenta covers the cervical opening) undergoing cesarean birth leads to a significant yet modest reduction in severe bleeding after delivery with no evidence ...
16 hours ago
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Popular weight loss and anti-inflammatory drugs may help prevent common heart rhythm disorder
Researchers at Ben-Gurion University of the Negev (BGU) have identified how two different classes of medication—the GLP-1 receptor agonist semaglutide and the anti-inflammatory drug colchicine—act on the heart to prevent ...
11 hours ago
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Semaglutide may improve motivation with major depressive disorder
Treatment with semaglutide significantly improves measures of motivation in patients with major depressive disorder (MDD), according to a study published April 29 in JAMA Psychiatry.
12 hours ago
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Alzheimer's therapeutic advancements may be financially inaccessible
A newly published study shows that while disease-modifying therapies (DMTs) may offer substantially greater health benefits than usual care, their real-world impact will depend on whether they are priced in ways that health ...
20 hours ago
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Cannabis: It's medicine if you're rich enough, a crime if you're not
In Britain, whether cannabis is treated as medicine or a crime may depend less on medical need than on the ability to pay. In 2018, the UK government changed drug policy, allowing specialist doctors to prescribe cannabis-based ...
23 hours ago
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New UK drug approval pathway benefits industry over patients, argues expert
A new UK drug approval pathway, designed to speed up the availability of new medicines, benefits industry over patients and the NHS, argues an expert in The BMJ. The pathway aligns regulatory review by the Medicines and Healthcare ...
16 hours ago
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No refrigeration needed for next-gen malaria vaccine
Malaria is a deadly disease killing more than half a million people every year, but a new vaccine is showing promise as it not only offers long-lasting strong protection but also inhibits transmission of malaria by mosquitoes. ...
May 13, 2026
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Continuing tirzepatide at full dose helps preserve weight loss over 112 weeks
New research presented at the European Congress on Obesity (ECO 2026) in Istanbul, Turkey (12–15 May) and published in The Lancet shows that people who have lost weight using the maximum tolerated dose (MTD) of tirzepatide ...
May 13, 2026
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New guideline aims to reduce severe allergic reactions to epilepsy drugs
Researchers from the Center of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx) have published a new prescribing guideline aimed at reducing the incidence of serious allergic reactions to common ...
May 13, 2026
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Existing drug shows promise for memory and decision-making issues affecting most schizophrenia patients
Schizophrenia is a serious brain disorder that causes confused thinking, severe memory problems, and hallucinations. It affects about 23 million people worldwide, with cognitive dysfunction present in over 80% of patients. ...
May 12, 2026
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Centuries-old medicine benefits heart failure patients, studies show
A low dose of digoxin ensures that people with heart failure are hospitalized and die less frequently. This emerges from three studies led by UMCG cardiologists Dirk Jan van Veldhuisen, Kevin Damman, and Peter van der Meer. ...
May 12, 2026
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The magic of mushrooms: Psychedelic psilocybin shows promise for treating cocaine addiction
Cocaine addiction treatment has found a surprising new contender in the highly regulated substance psilocybin, a naturally occurring psychedelic compound found in mushroom species popularly known as magic mushrooms or shrooms. ...
HIV reveals more than 100 escape mutations against promising antibody therapies
Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily doses of antiretroviral drugs. In one recent clinical study of bNAbs identified ...
May 12, 2026
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Trump promised cheaper drugs. Some prices dropped. Many others shot up
Since his second term started, President Donald Trump has announced, negotiated or floated a flurry of initiatives aimed at taming the excesses of the pharmaceutical industry.
May 12, 2026
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New meta-analysis finds no increased risk to children's brain development from fathers' use of valproate
A comprehensive review of existing research shows no evidence that men's use of the anti-seizure medication valproate increases the risk of neurodevelopmental disorders—such as autism and ADHD—in their children.
May 12, 2026
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Amputation rates on the rise for opioid-, non-opioid-related hospitalizations
Among opioid-related and non-opioid-related hospitalizations, amputation rates increased from 2016 to 2022, with greater increases seen among opioid-related hospitalizations nationally, according to a research letter published ...
May 12, 2026
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Study shows use of obesity drugs alongside behavioral intervention is associated with reduced 'food noise'
New research presented at this year's European Congress on Obesity in Istanbul, Turkey, shows that use of obesity drugs alongside behavioral interventions leads to a larger drop in so‑called food noise than in those using ...
May 12, 2026
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Are your meds and DNA a bad match? This test alerts clinicians
Differences in people's genes can affect how they respond to medications, including how well a drug works and the chances of side effects. About 1 in 10 of prescriptions given to patients outside the hospital don't work as ...
May 12, 2026
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AI joins the quest to find new treatments for rare diseases
Rare neuromuscular diseases often lack treatments because developing targeted drugs is slow, costly and risky for companies. A new approach using AI and stem cell models could finally shift the balance.
May 12, 2026
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Caffeine may influence the way the brain responds to touch
Many people begin each day with a steaming cup of joe to shake off the morning fog and jump-start their brain. Whether it's a shot of espresso or a frothy latte, that caffeine hit is famous for boosting alertness. However, ...
RNA therapy slows harmful heart remodeling after heart attack in clinical trial
Following an acute heart attack, pathological remodeling processes occur in the heart. One consequence is so-called left ventricular systolic dysfunction, in which the pumping function of the left ventricle is impaired. To ...
May 11, 2026
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