Last update:
Clinical pharmacology news
Cancer drug reduces early Alzheimer's-like brain hyperconnectivity in lab tests
Neuroscientists at King's College London have pinpointed a mechanism behind the increased neural connectivity observed in the very early stages of Alzheimer's disease. Published in Translational Psychiatry, the study also ...
6 hours ago
0
0
Hidden blood mutations drive severe inflammatory bowel disease, but a new treatment target is in sight
Indiana University School of Medicine scientists have uncovered new evidence that an age-related blood condition may contribute to inflammatory bowel disease (IBD). Their findings suggest that a new drug strategy targeting ...
2 hours ago
0
0
Human intestinal cell model enables precise detection of drug-induced barrier damage
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity during the preclinical stage ...
8 hours ago
0
0
Team approach, low-cost interventions lead to major reduction in opioid prescriptions after surgery
A novel team approach founded on a culture change among clinicians and doctor-patient communication successfully reduced post-surgical opioid use, a new study led by University of Rochester Medical Center (URMC) researchers ...
9 hours ago
0
0
Study reveals how antibiotic use during leukemia treatment reshapes the gut microbiome
Patients undergoing intensive chemotherapy for acute myeloid leukemia are routinely treated with multiple antibiotics to prevent infection, a practice that new research from Texas A&M University shows can significantly reshape ...
11 hours ago
0
0
Study highlights stroke risk linked to recreational drugs, including among young users
The recreational drugs cannabis, cocaine and amphetamines significantly increase the risk of stroke—including among younger users—Cambridge researchers have concluded after analyzing data from more than 100 million people.
Mar 8, 2026
0
0
A potential broad coronavirus drug target: Blocking tRNA-modifying enzymes slows viral proteins
Coronaviruses not only use the machinery of the human cells they infect: they modify them to achieve optimal conditions to produce viral proteins and thus spread more quickly. This is the main conclusion of a study by Pompeu ...
Mar 7, 2026
0
0
How do GLP-1 agonists affect gene expression?
GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and treat diabetes, the drugs were later found to promote weight loss and improve cardiovascular health. ...
Mar 6, 2026
0
1
Creating less trippy, more therapeutic 'magic mushrooms'
Psilocybin—the psychoactive compound in "magic mushrooms"—is gaining scientific attention for its potential in treating neuropsychiatric conditions including depression, anxiety, substance use disorders and certain neurodegenerative ...
Mar 6, 2026
0
1
PET imaging study reveals how ketamine relieves treatment-resistant depression
Major depressive disorder (MDD) is one of the leading causes of disability worldwide, and approximately 30% of patients develop treatment-resistant depression (TRD), a condition that does not respond adequately to conventional ...
Mar 6, 2026
0
0
Smart combinations of antibiotics can slow down resistance
When a bacterium becomes resistant to one antibiotic, it may sometimes become more sensitive to another. This biological side-effect offers an unexpected opportunity in the fight against antibiotic resistance.
Mar 6, 2026
0
1
Temporal lobe epilepsy: A new strategy to correct abnormal electrical activity
Many patients suffer from epilepsy that cannot be controlled by current medications. Surgical removal of epileptogenic brain regions is effective in only about half of cases, and not all patients are eligible for the procedure. ...
Mar 6, 2026
0
0
White House autism briefing linked to swift shifts in prescribing patterns
A White House briefing in September 2025 that raised concerns about acetaminophen use during pregnancy and promoted the drug leucovorin as a potential autism treatment was followed by sharp changes in how doctors prescribed ...
Mar 6, 2026
1
0
Spray-on 'immune-shield' coats transplant organs to curb rejection
A new technology has been developed to suppress immune rejection, the biggest challenge in organ transplantation, without causing systemic side effects. A research team from Pohang University of Science and Technology (POSTECH) ...
Mar 6, 2026
0
0
Intracellular signaling proteins emerge as a key target in drug development
In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug discovery. The focus is on the targeted modulation of certain intracellular signaling proteins as a strategy ...
Mar 6, 2026
0
0
Anti-obesity treatment could cost as little as $3 per month: Study
A blockbuster anti-obesity and diabetes drug could cost as little as $3 per month to manufacture once it goes off patent later this month, researchers said Friday, providing a major opportunity to boost health in low- and ...
Mar 6, 2026
0
1
Short bowel syndrome has no drugs: A new compound could cut liver risk
When parts of the small intestine are diseased or die, the treatment can involve surgically removing the affected tissue. Although lifesaving, the procedure—referred to as a radical small bowel resection—can lead to long-term ...
Mar 6, 2026
0
0
AAOS: GLP-1 receptor agonist use increases five-year risk for osteoporosis
Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for type 2 diabetes and obesity is independently associated with a significantly increased five-year risk for osteoporosis, gout, and osteomalacia compared ...
Mar 6, 2026
0
0
Trial suggests GLP-1 combo therapy cuts fat while preserving muscle in obesity
A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also preserving lean mass, ...
Mar 5, 2026
0
1
Single saRNA shot helps with healing after a heart attack
For people who have survived a heart attack, the notion of one shot in the arm to help the heart heal, for weeks after, may seem far-fetched. But thanks to a team of researchers, including a Texas A&M University professor, ...
Mar 5, 2026
0
0
Combination therapy reduces effects of 'zombie cells' in diabetic kidney disease, research finds
Mayo Clinic researchers have identified a drug-and-supplement combination therapy that is capable of reducing the harmful effects of senescent cells—also known as "zombie cells"—in diabetic kidney disease. In eBioMedicine, ...
Mar 5, 2026
0
0
Cannabis compounds show promise in fighting fatty liver disease
Researchers have discovered that non-psychoactive cannabis compounds, CBD and CBG, can significantly reduce liver fat and improve metabolic health. The study reveals that these compounds work by creating a backup energy reserve ...
Mar 5, 2026
0
2
What to know about how GLP-1 medications might fight addiction
The blockbuster GLP-1 drugs that have reshaped the treatment of diabetes and obesity may help prevent multiple substance use disorders—and reduce the tragic outcomes they cause, a large new study finds.
Mar 5, 2026
0
0
Testosterone therapy could mean trouble for knee replacement patients, study warns
Testosterone therapy is booming in the U.S., but it might bring higher risks for people undergoing knee replacement surgery, a new study says.
Mar 5, 2026
0
0
GLP‑1 drugs like Ozempic may lower the risk of addiction: New study
A class of medications best known for treating diabetes and obesity may also reduce the risk of addiction—and help people who already have one, a new study shows.
Mar 5, 2026
0
0
