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Clinical pharmacology news
Placing battery tech directly on tissue to deliver lithium ions for targeted pain relief
A new study from the University of Chicago taps an ingredient most often used in the lithium-ion batteries that power our devices to open new avenues in biomedical technology. Lithium plays vital roles in the body, but taking ...
35 minutes ago
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Blocking NOX-1 enzyme may extend ketamine's antidepressant effects
Treatment-resistant depression affects a large proportion of people with major depressive disorder, and while ketamine offers rapid relief, its antidepressant effects fade within a few weeks. Now, researchers from Japan have ...
55 minutes ago
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20,000 lab-grown human retinas reveal how cone photoreceptor cells resist degeneration
Scientists led by Botond Roska at the Institute of Molecular and Clinical Ophthalmology Basel (IOB) and collaborators have identified genetic pathways and compounds capable of protecting cone photoreceptors from the degeneration ...
4 hours ago
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FDA weighs expanding what can go into supplements
What's in your supplements could soon change.
1 hour ago
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Can I drive when taking medicinal cannabis? Is it safe?
Your doctor has just prescribed medicinal cannabis. You think it's helping. But you rely on your car to get to work and pick up the kids.
2 hours ago
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Researchers compare brain markers affected by brief versus lengthy exposure to alcohol in mice
Erica Periandri and Gabor Egervari, from Washington University in St. Louis, led a study to explore how alcohol exposure in male mice influences gene expression and mechanisms that regulate gene function—or epigenetics.
2 hours ago
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FDA warns biotech firm over cancer drug claims
The U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.
Mar 29, 2026
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Solving the oxygen problem in cell-based drug delivery
Implanting living cells as long-term drug producers could transform treatment for numerous diseases, but it is difficult to house the tiny workers in quantities high enough to ensure dosage needs are met while also keeping ...
Mar 28, 2026
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AI-powered 'lab-on-a-chip' platform may enable same-day treatment decisions for pediatric patients
Scientists at the University of Utah (the U) have developed a new "lab-on-a-chip" device that uses artificial intelligence to rapidly predict cancer cell sensitivity to targeted therapies for children with T-cell acute lymphoblastic ...
Mar 27, 2026
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Treating disease at birth: How a brief spike in testosterone sets the trajectory for disease that appears decades later
Spinal and bulbar muscular atrophy (SBMA) is a rare inherited disease that causes progressive muscle weakness and wasting in men. Patients typically develop early symptoms such as hand tremors in their 30s, but diagnosis ...
Mar 27, 2026
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Strong patient diversity in biobanks reveals new genetic links to disease risk and treatment response
A new study by UCLA Health published in Cell presents a major advancement in the future of personalized medicine by pinpointing new connections between people's genes, disease risk and medicine response by using a clinically ...
Mar 27, 2026
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TIE2 protein emerges as potential drug target to prevent development of dangerous blood vessel defects in brain
Researchers in the Perelman School of Medicine at the University of Pennsylvania have identified a cell surface receptor protein called TIE2 as the missing link between two key signaling pathways that drive the growth of ...
Mar 27, 2026
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Influencers promoting prescription drugs on social media pose public health risks
In today's world, attention is increasingly focused on social media and its influencers, a shift reflected in the industry's rapid growth and a global market projected to surpass $32 billion. The marketing teams of pharmaceutical ...
Why some cancer therapies don't work for all patients: A tumor backup survival pathway
Drugs that block enzymes called tyrosine kinases are among the most effective targeted therapies for cancer. However, they typically work for only 40% to 80% of the patients who would be expected to respond to them. In a ...
Mar 26, 2026
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Over the past decade, early-stage drug innovation has shifted toward China, researchers find
Early-stage drug development worldwide has nearly doubled over the past decade and shifted from a U.S.-dominated model to a dual hub centered in the United States and China, according to new research described by Georgetown ...
Mar 26, 2026
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Kratom calls skyrocket to nation's poison centers
Calls to poison centers about kratom, a drug widely available in vape shops and gas stations, increased more than 1,200% between 2015 and 2025, with a corresponding rise in hospitalizations, an alarming new UVA Health analysis ...
Mar 26, 2026
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Weight-loss medications may affect some complications after panniculectomy
For patients undergoing body contouring surgery to remove excess abdominal skin after massive weight loss, use of GLP-1 weight-loss medications may have mixed effects on complication risks, suggests a study in the April issue ...
Mar 26, 2026
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Common blood pressure drug can boost cancer treatment
In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP, investigators found that the FDA-approved blood pressure drug telmisartan can significantly enhance the cancer-killing ...
Mar 25, 2026
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Passion fruit–derived molecule shows promise as a future Alzheimer's drug candidate
Four years ago, a research group at the University of Oslo made what would turn out to be a major discovery. They found that an extract from passion fruit had the potential to slow the development of Alzheimer's disease. ...
Mar 25, 2026
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New medicine piggybacks onto fat absorption pathways to allow oral delivery in major depressive disorder
Monash University and Seaport Therapeutics have developed a new approach to delivering drug molecules that piggybacks onto natural fat absorption pathways to allow oral delivery of some drugs previously requiring injection. ...
Mar 25, 2026
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Could a new type of weight‑loss pill shake up the market? Here's what to know about orforglipron
A new type of daily pill has proven more effective for weight loss and blood sugar control than its currently available counterparts, according to a recent trial. The drug, known as orforglipron, could be a game-changer in ...
Mar 25, 2026
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Dengue fever is a growing problem: Why it's so hard to beat with vaccines
Dengue, a mosquito-borne disease, affects millions of people every year across Asia, Africa and Latin America. And it's expanding geographically as warmer temperatures and urban growth allow mosquito populations to thrive ...
Mar 25, 2026
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FDA approves Icotyde for moderate-to-severe plaque psoriasis
The U.S. Food and Drug Administration has approved Johnson & Johnson's Icotyde (icotrokinra), an interleukin-23 (IL-23) receptor antagonist, for the treatment of moderate-to-severe plaque psoriasis in adults and pediatric ...
Mar 25, 2026
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Dramatic reduction in prescribing of hepatitis C antivirals may leave many curable patients untreated
Direct-acting antivirals (DAAs) can cure hepatitis C (HCV) in more than 95% of individuals treated. But only 1 in 3 people with HCV in the U.S. receive treatment within a year of diagnosis. A new study by investigators from ...
Mar 25, 2026
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FDA-approved fatty liver drug also suppresses liver tumors in mice
A research team from the Department of Pathology, School of Clinical Medicine, LKS Faculty of Medicine of the University of Hong Kong (HKUMed), in collaboration with the HKU State Key Laboratory of Liver Research, has found ...
Mar 24, 2026
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