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Clinical pharmacology news

WHO approves first malaria treatment for infants

The World Health Organization announced Friday that it had given prequalification approval to a malaria treatment for newborns and infants for the first time.

Exploiting a new vulnerability that targets 'zombie' cells as an anticancer therapy

A new set of drugs exploit a recently revealed weakness in "zombie-like"—or senescent—cells that could lead to new treatments for cancer and age-associated diseases. The study from the MRC Laboratory of Medical Sciences (LMS) ...

New cellular target prevents hepatitis E infection

An international team of researchers has identified a promising new approach for treating infections with the Hepatitis E virus (HEV). At the center of the study is the drug Apilimod, which specifically blocks the entry of ...

US eases access to marijuana for medical use

The US government on Thursday made it easier for Americans to use cannabis for medical reasons by reclassifying the drug and enabling more research into its safety and efficacy.

Researchers explore new approach to multivirus drug development

Wanted: a cheap, multipotent treatment for viral infections. Must be able to handle new or unfamiliar strains, or (even better) a broad range of viruses—whatever comes along, in other words. Must be impervious to viral attempts ...

'Frankenproteins' offer hope in fighting cancer

Lab-created "frankenproteins" developed by a team of scientists at the University of Toronto Mississauga offer hope for safer and more effective cancer treatments in the future. The protein-based drugs being developed by ...

Molecular keyhole sheds light on pain and epilepsy

Researchers at VIB, VUB, and KU Leuven have identified a tiny binding site, a molecular "keyhole," in the TRPM3 ion channel, a crucial sensor in pain signaling. TRPM3 is also linked to rare neurodevelopmental disorders and ...