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Clinical pharmacology news
Psilocybin cuts nerve pain for weeks and boosts gabapentin in mice
A single dose of psilocybin, the active compound in magic mushrooms, reduces nerve pain for up to a month and makes a widely used painkiller work more effectively, University of Reading research has found.
6 hours ago
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Cholesterol-craving cancers need lipid enzymes to use metabolites for growth, study shows
While many American adults are trying to reduce cholesterol levels, certain cancerous tumors have a relentless appetite for the metabolite. Some tumor cells use as much cholesterol as they can access to accelerate their growth ...
6 hours ago
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A once-daily pill takes aim at measles, croup and other dangerous viruses
A new oral antiviral drug candidate has been developed for the treatment of diseases caused by orthoparamyxoviruses, such as measles and croup syndrome, according to a study published by researchers in the Center for Translational ...
6 hours ago
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Common epilepsy drug disrupts early brain growth in human organoids after 30-day exposure
It is known that the antiepileptic drug valproate increases the risk of developmental disorders in unborn children. A study conducted by the Karlsruhe Institute of Technology (KIT), the Heidelberg Academy of Sciences and ...
7 hours ago
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Nitric oxide rewires gene expression in the brain, offering new insight into Alzheimer's disease
Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the functional genome—the working portion of our DNA that helps make each person unique. Put simply, a single ...
8 hours ago
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New indicator for response to therapy in pediatric cancers identified
A study by researchers at the University of Birmingham has identified a new biomarker for response to a specific cancer therapy, treating children with Ewing Sarcoma and other tumor types. The study, which is a Phase I/II ...
2 hours ago
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Weight loss drug semaglutide helps patients who do not respond to bariatric surgery, research finds
Metabolic/bariatric surgery is a highly effective treatment for people living with severe obesity and/or metabolic health conditions, which works through changing the anatomy of the digestive system and thereby changing the ...
8 hours ago
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Researchers identify avenue for enhanced GLP-1-induced weight loss
A team of researchers at the National Institutes of Health (NIH) have unveiled new details about the events GLP-1 receptor agonists trigger within neurons, which have been largely unexplored until now. A study in mice identified ...
15 hours ago
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A single dose of psilocybin eased depression symptoms for months, our study found
A single dose of psilocybin eased symptoms of depression within days, with benefits lasting for more than three months compared to placebo, our new study has found.
9 hours ago
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EU regulator approves pill form of Novo Nordisk's Wegovy weight loss drug
Novo Nordisk has obtained approval for the pill form of its popular Wegovy anti-obesity drug in the European Union, the bloc's medicines regulator said on Friday.
5 hours ago
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Ozempic and other GLP-1 RAs could slow progression of some cancers, data suggest
Real-world data show that GLP-1 receptor agonists (GLP-1s) may reduce metastatic progression of certain obesity-related cancers, namely lung, breast, colorectal, and liver cancers. In addition, GLP-1 receptor (GLP-1R) expression ...
12 hours ago
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Researcher develops 'smart, tiny bubbles' to treat cancer and heart disease
A cell 500 times thinner than a human hair could heal hearts and kill cancer cells, thanks to a patent-pending technology created by a University of Central Florida researcher and now licensed to a university donor in hopes ...
22 hours ago
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Novel combination therapy could reduce leukemia relapse rate, extending window for bone marrow transplants
A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has developed a novel combination therapy that significantly improves treatment ...
May 21, 2026
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Dementia drug may help treat alcohol withdrawal
A new study from researchers at the University of Kentucky's Sanders-Brown Center on Aging is exploring whether a drug originally developed to combat neuroinflammation in dementia could also help reduce the harmful brain ...
May 21, 2026
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Oral drug proves highly effective against chemotherapy-related low platelets in GI cancer trial
An oral medication already approved for thrombocytopenia in patients with liver disease significantly improved platelet recovery and helped patients with gastrointestinal cancers maintain platelet counts needed to continue ...
May 21, 2026
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Scientists make surprising discovery and find a possible new ally in the opioid crisis
Scientists at Bowling Green State University recently made a series of discoveries that could have wide-ranging implications for the future of the national opioid crisis. Through a partnership with the Toledo Lucas County ...
May 20, 2026
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Can supplements containing NMN, NAD+ and resveratrol really slow aging? Here's what the evidence says
As more people look for ways to stay younger for longer, the supplement industry has moved beyond creams and cosmetic fixes to something more ambitious: products that claim to slow aging by acting on cellular processes.
May 20, 2026
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Study suggests novel way to protect aging brains after surgery
Many people experience temporary cognitive impairment immediately after surgery. In people over age 60, however, about 1 in 10 continues to experience deficits in learning, memory, and executive function for more than three ...
May 20, 2026
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How different SSRIs affect metabolism in early brain development
A new study from Karolinska Institutet shows that different SSRI medications affect metabolic processes in developing nerve cells in distinct ways. Alterations in energy metabolism, oxidative stress and lipid profiles suggest ...
May 19, 2026
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Sedative choice in pediatric intensive care may influence long-term neurocognitive outcomes
A new Penn Nursing study suggests that the specific sedatives used during critical illness in early childhood may have long-term implications for a child's neurocognitive development. Martha A.Q. Curley, Ph.D., RN, FAAN, ...
May 19, 2026
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Oral GLP-1s without fasting or reduced efficacy: Delivery approach protects peptide-based drugs from stomach acid
Biomedical engineers at Duke University have developed a new approach to delivering GLP-1 medications orally that does not require fasting and maintains their efficacy. The technique could also be useful for any pharmaceutical ...
May 19, 2026
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Which patients benefit most from tirzepatide GLP-1 for obesity and obstructive sleep apnea?
Tirzepatide GLP-1 medication is known to improve sleep apnea for people with both obstructive sleep apnea (OSA) and obesity, but not all patients benefit equally. Now, new research presented at the 2026 ATS International ...
May 19, 2026
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New research finds low-dose buprenorphine may help sustain ketamine's benefits for suicidal ideation
New research published in the American Journal of Psychiatry finds that low-dose buprenorphine, given after a single ketamine infusion, significantly sustained reductions in suicidal ideation in adults with major depressive ...
May 19, 2026
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Race to find vaccines, treatments for Ebola strain behind outbreak
An escalating outbreak of a rare Ebola strain in the Democratic Republic of Congo has kicked off a race to find vaccines and treatments that can be quickly tested and rolled out to save lives and stem the crisis.
May 19, 2026
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Statistical method may overstate Alzheimer's drugs' cognitive benefits by 29 times
A statistical approach being used to support a new class of Alzheimer's drugs may lead to overstated claims about how the drugs work, according to a new study led by researchers at the Brown University School of Public Health.
May 18, 2026
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