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Clinical pharmacology news
This laser breakthrough supercharges osteoporosis treatment by exposing bone's hidden growth switch
A research team has discovered a new mechanism and drug combination strategy that can effectively treat osteoporosis, a representative disease of super-aging societies. The research findings were published on April 2 in Bone ...
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New drug doubles 1-year survival in pancreatic cancer trial
Pancreatic cancer is one of the deadliest cancers and among the hardest to treat, with most patients surviving less than a year after diagnosis. But a new drug developed at Northwestern University may soon help patients live ...
9 hours ago
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Antibiotics can trigger bacteria to release bubbles of inflammation tinder, making it harder to treat infection
Antibiotics are designed to kill harmful bacteria and help the body recover from infection. But some antibiotics may also push bacteria to release tiny particles that can make inflammation worse.
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GLP-1 medicine improves liver health independent of weight loss, study finds
Researchers at Toronto's Sinai Health have found that semaglutide—the active ingredient in popular weight loss drugs that mimic the gut hormone GLP-1—acts directly on a subset of liver cells to improve organ function and ...
3 hours ago
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Scientists make Parkinson's drug from plastic in world first
It's easy to see discarded plastic as nothing more than waste. Much of it ends up in landfill, breaking down into microplastics that seep into water supplies and threaten the environment, and potentially human health. But ...
4 hours ago
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Students publish paper validating optimal caffeine dosage for newborns with heart disease
Montana State University students published a paper alongside Duke University researchers in the Journal of Pediatric Pharmacology and Therapeutics this spring, validating a study on the optimal caffeine dosage for newborn ...
13 hours ago
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Researchers demonstrate drug's effectiveness in drawing out dormant HIV from immune cells
Human immunodeficiency virus-1 (HIV) is one of the most challenging viruses for doctors to treat. Even with effective antiretroviral therapy, immune cells infected with HIV can hide and lie inactive in certain areas of the ...
21 hours ago
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Pain-sensing neurons mapped in unprecedented detail, pointing to new chronic pain drug targets
One in five people worldwide suffers from chronic inflammatory pain. Meanwhile, about two thirds of those affected find little relief from existing pain medications; new therapeutic approaches are urgently needed. "We first ...
19 hours ago
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Environmental enrichment lowered stress hormones tied to fentanyl relapse in rats
Combating the opioid crisis relies on identifying new prevention strategies for problematic fentanyl use. In a collaboration between Washington State University and Washington University in St. Louis, researchers led by Jose ...
Apr 13, 2026
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As RSV evolves, a two‑pronged antibody cocktail aims to stay ahead
Scientists in China have developed a two-antibody cocktail to treat respiratory syncytial virus, or RSV, that in laboratory studies prevented the virus from developing drug resistance—a persistent problem with current therapies ...
Coffee's sweet spot may help mental health in the long run
Your morning cup of coffee may be more than just a pick-me-up. It may also be a simple boost for your mental well-being. In a recent study, researchers from Fudan University, China, wanted to find out whether the amount of ...
New drug combination doubles down on Alzheimer's treatments
A new study has found that combining the current medications for Alzheimer's disease with small molecules derived from micronutrients found in grapes, berries, peanuts and turmeric is a safer and more effective way to treat ...
Apr 11, 2026
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Experimental drug cuts Parkinson's-linked protein up to 60% in early trial
An experimental drug designed to silence a gene strongly linked to Parkinson's disease has shown encouraging effects in a first-in-human clinical trial, according to a study published in Nature Medicine. The drug, known as ...
Apr 11, 2026
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Injectable peptides are the new anti‑aging trend. But what evidence do we have they're safe for humans?
Injectable peptides are the new anti-aging trend sweeping the beauty industry. These compounds are promoted on social media as tools for skin repair, collagen production and "cellular rejuvenation." They are widely available ...
Apr 11, 2026
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AI scans 400,000 Reddit posts to flag overlooked GLP-1 side effects
By using AI to analyze more than 400,000 Reddit posts, Penn researchers have identified patient-reported symptoms associated with GLP-1s, the popular weight-loss and diabetes drugs semaglutide and tirzepatide, that may not ...
Apr 10, 2026
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How the blood-brain barrier opens: Two proteins may guide future drug delivery
The cells that line the blood vessels in our brains are highly selective. By deciding which molecules are allowed in and out of our most important organ, the barrier these cells form is critical for keeping us alive. But ...
Apr 9, 2026
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Without the right tests, the best medicines make no difference
A new analysis from UC San Francisco argues that diagnostics—medical tests that match patients to the appropriate treatment—are being overlooked both in the United States and around the world. This is slowing progress against ...
Apr 9, 2026
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Why autism affects more men than women—MDGA1 gene mutation may help explain
Researchers have discovered that a mutation of the MDGA1 gene, a key factor modulating the connections and characteristics between nerve cells, serves as a new cause of autism spectrum disorder (ASD), and suggested the possibility ...
Apr 9, 2026
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Psilocybin mushrooms are going mainstream, but scientific research and regulation lag behind
Amid a renaissance in the science of psychedelics, public interest in psilocybin—or magic mushrooms, as they've long been known—is surging.
Apr 9, 2026
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Flu treatment shields lungs, cuts pneumonia risk
A new flu treatment could drastically reduce one of flu's deadliest complications—bacterial pneumonia—by helping the lungs defend themselves, rather than targeting the virus directly. Influenza specialist Associate Professor ...
Apr 9, 2026
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Some common IBS treatments are linked to a higher risk of death, say study
A large, long-term study led by Cedars-Sinai Health Sciences University investigators suggests that some medications commonly prescribed to treat irritable bowel syndrome (IBS)—including antidepressants—may be associated ...
Apr 8, 2026
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Parkinson's add-on drugs may spur gut bacteria that break down levodopa, study finds
Levodopa—the gold-standard treatment for Parkinson's disease—increases dopamine in the brain. But as the disease progresses in severity, patients often need to take additional drugs to manage their symptoms. One class of ...
Apr 8, 2026
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Antibody drugs with strong immune cell binding linked to allergic reactions
Antibody therapeutics are laboratory-made proteins designed to work like the body's natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including cancer cells or inflammatory ...
Apr 8, 2026
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Long-term opioid prescribing has fallen, but millions still receive extended opioid therapy
Long-term opioid prescribing has fallen in the United States over the last decade, but millions of patients still received opioids for 90 days or longer in 2023, according to a new research letter in JAMA led by University ...
Apr 8, 2026
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Genetic predictors for GLP-1 weight loss efficacy and side effects identified
23andMe Research Institute, a nonprofit medical research organization, announced the publication of a study that identifies genetic predictors for GLP-1 weight loss efficacy and side effects. GLP-1 receptor agonists, including ...
Apr 8, 2026
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