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Clinical pharmacology news
Erucamide molecule strengthens the eye's response to damage in retinal disease
Many conditions that cause vision loss share a common feature: the gradual breakdown of the retina, the light-sensing tissue at the back of the eye. Although scientists know some of the structural changes that ensue as this ...
8 hours ago
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Protective human antibodies target West Nile and related viruses
West Nile virus (WNV) is transmitted by mosquitoes and is increasingly relevant for Europe and worldwide. It can cause severe brain infection and death, yet there is no specific antiviral treatment or approved human vaccine. ...
9 hours ago
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Can supplements keep your brain sharp? Why the evidence is more complicated than it seems
Many of us would like to keep our brains sharp as we get older. That has helped create a growing market for "brain-health" supplements. These include fish oil capsules and postbiotics, the beneficial, nonliving compounds ...
13 hours ago
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Engineers test, validate novel method to improve pharmaceutical research and development
A patent-pending innovation created and validated in Purdue University's College of Engineering could strengthen pharmaceutical research and development in the areas of batch verification, encapsulation efficiency screening ...
16 hours ago
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Weight‑loss drugs like Ozempic could work for addiction too—and we finally know how
For many people, the thought of a tasty burger or a cold pint of beer conjures a vivid mental image and drives behavior. This link between thinking and doing serves a clear function—it motivates us to get the necessities ...
17 hours ago
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Study links real-time prescription monitoring to drop in high risk medication prescribing
Research shows that patients who see multiple doctors for high-risk medicines face increased risks of dependence, overdose and death, as well as reduced continuity of care.
20 hours ago
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Clues to psilocybin's epigenetic effects on people with alcohol use disorder
Some psychedelics, psychoactive substances that alter people's mood, perceptions and mental processes, were recently found to be promising alternative treatments for some mental health disorders. The substance that has attracted ...
Common dizziness drug class shows promise for treating vestibular migraine
A new study finds that a class of oral and intranasal medications known as gepants may be an effective and well-tolerated treatment for vestibular migraine (VM). The findings are published in the journal Otolaryngology–Head ...
Jun 21, 2026
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Mass spectrometry platform could shrink cancer drug discovery cycle to four hours
Researchers at the Purdue Institute for Cancer Research (PICR) have developed a next-generation technology platform designed to accelerate one of the slowest and most challenging stages of cancer drug discovery: identifying ...
Jun 20, 2026
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The over‑50s are most likely to overdose. Here's how older people use drugs
When many of us think about drug overdose, we picture young people at a music festival or people dependent on street heroin. But the latest figures from the Penington Institute show older Australians are increasingly dying ...
Jun 20, 2026
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Hibernation-like cooling after stroke may reduce brain damage
Our body loves the state of homeostasis, where everything is in perfect equilibrium, from temperature to pH levels to fluid balance. As soon as the body's core temperature drops below 95°F (35°C) and stays there for a long ...
Gene therapy shows promise in ARC syndrome, a deadly childhood liver disease
A new gene therapy has been used to successfully treat a deadly childhood liver disease in mice that model the disease, according to researchers at UCL and Great Ormond Street Hospital. Arthrogryposis, renal dysfunction and ...
Jun 19, 2026
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FDA approves another over-the-counter naloxone nasal spray
The U.S. Food and Drug Administration has approved another over-the-counter intranasal naloxone product, Rextovy (naloxone hydrochloride), for the emergency treatment of opioid overdose. The nonprescription approval was granted ...
Jun 19, 2026
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Engineered probiotic heads to human trials
A probiotic bioengineered by UBC Okanagan researchers to thrive in the inflamed gut is set to enter human clinical trials in Australia this summer, capping a decade-long effort to turn a beneficial bacterium into a treatment ...
Jun 19, 2026
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Examining the cardioprotective effects of heart failure treatments in patients with cancer
Patients receiving cancer treatment often face the added complication of side effects affecting the heart, which can lead to the need to discontinue anticancer therapy, reducing its effectiveness. Researchers from the Erasmus ...
Jun 19, 2026
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Epigenetic drugs could protect blood vessels in obesity and diabetes
People with obesity and type 2 diabetes are at high risk of blood vessel damage. This risk depends not only on the genes a person carries, but also on how they are "read." By changing the epigenetic reading signals in the ...
Jun 18, 2026
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AI screens 6 million compounds to uncover two leads against drug-resistant gonorrhea
With tens of millions of annual cases, gonorrhea is the second most frequently reported sexually transmitted infection (STI). In the U.S. alone, more than 600,000 cases are reported each year. If left untreated, gonorrhea ...
Jun 18, 2026
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Global clinical trial reveals safest, most effective antibiotics for golden staph bloodstream infections
An international clinical trial has identified the optimal antibiotics for golden staph bloodstream infections, a breakthrough set to reshape treatment for the life-threatening condition. The SNAP Trial found that the standard ...
Jun 18, 2026
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FDA panel backs first-of-its-kind flu vaccine using mRNA technology
A new kind of flu vaccine moved a step closer to the U.S. market Thursday as federal health advisers recommended approval of the first made with the same mRNA technology that was key to ending the COVID-19 pandemic.
Jun 18, 2026
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Rhythmic drug dosing may boost safety and efficacy in chronic liver disease
Metabolic dysfunction-associated steatohepatitis (MASH), primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are progressive chronic liver diseases linked to abnormal bile acid metabolism. Although ...
Jun 18, 2026
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The vaccines and treatments being developed for Ebola outbreak
There are no vaccines or treatments for the strain of Ebola that has killed more than 200 people in DR Congo and Uganda, but several are being urgently developed in the hope of reining in the outbreak.
Jun 18, 2026
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Cannabis caution as study finds increased psychosis risk for young people
Young people who use cannabis daily are up to four times more likely to develop psychosis than those who don't, according to an international study led by University of Queensland researchers. The review analyzed evidence ...
Jun 18, 2026
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Time for better opioid detoxification strategies, researchers say
Addiction services must urgently consider the way they offer support for those wanting to come off opioid substitutes through detoxification, according to researchers at Imperial College London.
Jun 18, 2026
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Legalizing cannabis increases use and addiction, unless it is tightly controlled, says research
Removing criminal penalties for possessing cannabis for personal use, or introducing tightly controlled legalization of cannabis, does not appear to increase levels of cannabis use. However, the commercial sale of cannabis ...
Jun 17, 2026
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Pakistani genomes reveal 34,000 knockouts that could explain why mouse-based drugs fail in humans
A comprehensive analysis of 173,303 genomes from Pakistan, published today in Nature, is upending how scientists understand human genetics and drug development. By identifying 34,000 people who are "human knockouts," with ...
Jun 17, 2026
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