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Clinical pharmacology news
Researchers identify avenue for enhanced GLP-1-induced weight loss
A team of researchers at the National Institutes of Health (NIH) have unveiled new details about the events GLP-1 receptor agonists trigger within neurons, which have been largely unexplored until now. A study in mice identified ...
2 hours ago
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Novel combination therapy could reduce leukemia relapse rate, extending window for bone marrow transplants
A research team from the Department of Medicine, School of Clinical Medicine, LKS Faculty of Medicine, the University of Hong Kong (HKUMed), has developed a novel combination therapy that significantly improves treatment ...
14 hours ago
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Researcher develops 'smart, tiny bubbles' to treat cancer and heart disease
A cell 500 times thinner than a human hair could heal hearts and kill cancer cells, thanks to a patent-pending technology created by a University of Central Florida researcher and now licensed to a university donor in hopes ...
10 hours ago
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Dementia drug may help treat alcohol withdrawal
A new study from researchers at the University of Kentucky's Sanders-Brown Center on Aging is exploring whether a drug originally developed to combat neuroinflammation in dementia could also help reduce the harmful brain ...
19 hours ago
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Oral drug proves highly effective against chemotherapy-related low platelets in GI cancer trial
An oral medication already approved for thrombocytopenia in patients with liver disease significantly improved platelet recovery and helped patients with gastrointestinal cancers maintain platelet counts needed to continue ...
14 hours ago
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Scientists make surprising discovery and find a possible new ally in the opioid crisis
Scientists at Bowling Green State University recently made a series of discoveries that could have wide-ranging implications for the future of the national opioid crisis. Through a partnership with the Toledo Lucas County ...
May 20, 2026
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Can supplements containing NMN, NAD+ and resveratrol really slow aging? Here's what the evidence says
As more people look for ways to stay younger for longer, the supplement industry has moved beyond creams and cosmetic fixes to something more ambitious: products that claim to slow aging by acting on cellular processes.
May 20, 2026
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Study suggests novel way to protect aging brains after surgery
Many people experience temporary cognitive impairment immediately after surgery. In people over age 60, however, about 1 in 10 continues to experience deficits in learning, memory, and executive function for more than three ...
May 20, 2026
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How different SSRIs affect metabolism in early brain development
A new study from Karolinska Institutet shows that different SSRI medications affect metabolic processes in developing nerve cells in distinct ways. Alterations in energy metabolism, oxidative stress and lipid profiles suggest ...
May 19, 2026
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Sedative choice in pediatric intensive care may influence long-term neurocognitive outcomes
A new Penn Nursing study suggests that the specific sedatives used during critical illness in early childhood may have long-term implications for a child's neurocognitive development. Martha A.Q. Curley, Ph.D., RN, FAAN, ...
May 19, 2026
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Oral GLP-1s without fasting or reduced efficacy: Delivery approach protects peptide-based drugs from stomach acid
Biomedical engineers at Duke University have developed a new approach to delivering GLP-1 medications orally that does not require fasting and maintains their efficacy. The technique could also be useful for any pharmaceutical ...
May 19, 2026
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Which patients benefit most from tirzepatide GLP-1 for obesity and obstructive sleep apnea?
Tirzepatide GLP-1 medication is known to improve sleep apnea for people with both obstructive sleep apnea (OSA) and obesity, but not all patients benefit equally. Now, new research presented at the 2026 ATS International ...
May 19, 2026
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New research finds low-dose buprenorphine may help sustain ketamine's benefits for suicidal ideation
New research published in the American Journal of Psychiatry finds that low-dose buprenorphine, given after a single ketamine infusion, significantly sustained reductions in suicidal ideation in adults with major depressive ...
May 19, 2026
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Race to find vaccines, treatments for Ebola strain behind outbreak
An escalating outbreak of a rare Ebola strain in the Democratic Republic of Congo has kicked off a race to find vaccines and treatments that can be quickly tested and rolled out to save lives and stem the crisis.
May 19, 2026
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Statistical method may overstate Alzheimer's drugs' cognitive benefits by 29 times
A statistical approach being used to support a new class of Alzheimer's drugs may lead to overstated claims about how the drugs work, according to a new study led by researchers at the Brown University School of Public Health.
May 18, 2026
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At 'most favored nation' prices, can Medicare break even on GLP-1 drugs?
In November 2025, the White House announced pricing deals with multiple pharmaceutical manufacturers to lower domestic prices for glucagon-like peptide-1 receptor agonist drugs (GLP-1RAs) including Ozempic, Wegovy, Mounjaro, ...
May 18, 2026
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Why an off-label autism drug suddenly took off, despite limited large-scale evidence
Researchers from the University of California San Diego found that prescriptions for leucovorin, a drug sometimes used off-label for autism spectrum disorder (ASD), rose sharply among children after widespread media attention ...
May 18, 2026
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New drug target identified for Fragile X syndrome
UCLA Health researchers have identified a potential drug target for treating Fragile X syndrome, the most common genetic cause of intellectual disability and autism that affects roughly one in 2,000 boys.
May 18, 2026
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Creatine improves physical performance but does not necessarily reduce inflammation, finds study
Creatine, one of the most popular supplements among gym-goers and athletes, does not appear to have the anti-inflammatory effect that many imagine. This conclusion comes from a systematic review and meta-analysis conducted ...
May 18, 2026
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Automation cuts prostate cancer drug candidate production from 6 hours to 38 minutes
A proof-of-concept study has created a blueprint for producing prostate cancer treatment more efficiently. Researchers at the University of Missouri, Cancer Targeted Technology (CTT) and Isotherapeutics Group (ITG) discovered ...
May 18, 2026
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FDA approves label expansion for Vyvgart, Vyvgart Hytrulo for generalized myasthenia gravis
The U.S. Food and Drug Administration has approved a label expansion for Vyvgart (efgartigimod alfa-fcab) and Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) for the treatment of adult patients with (gMG). The ...
May 18, 2026
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Scientists develop first-in-class drug candidate for chronic itch
Chronic itch is often described as an "invisible torment." It can persist for weeks or months, severely affecting sleep, mental health, and quality of life. In patients with cholestatic liver disease, chronic itch remains ...
May 18, 2026
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Clinical trial shows tezepelumab controls asthma in diverse patient population
The drug tezepelumab was shown to significantly reduce exacerbations in people with severe asthma in clinical trials. Now, a new study presented at the 2026 ATS International Conference shows that it is also safe and effective ...
May 18, 2026
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Japan pharmaceutical firm warns against rare diseases drug after deaths
A Japanese pharmaceutical firm has warned doctors against prescribing a drug for rare autoimmune diseases to new patients following the deaths of 20 people who took it.
May 16, 2026
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FDA official who scrutinized COVID shots and antidepressants is out in latest shake-up
A Food and Drug Administration official involved in scrutinizing the safety of antidepressants, COVID-19 vaccines and other widely used therapies has been removed from her role leading the agency's drug program.
May 16, 2026
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