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Clinical pharmacology news
No refrigeration needed for next-gen malaria vaccine
Malaria is a deadly disease killing more than half a million people every year, but a new vaccine is showing promise as it not only offers long-lasting strong protection but also inhibits transmission of malaria by mosquitoes. ...
8 minutes ago
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New guideline aims to reduce severe allergic reactions to epilepsy drugs
Researchers from the Center of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx) have published a new prescribing guideline aimed at reducing the incidence of serious allergic reactions to common ...
6 minutes ago
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Existing drug shows promise for memory and decision-making issues affecting most schizophrenia patients
Schizophrenia is a serious brain disorder that causes confused thinking, severe memory problems, and hallucinations. It affects about 23 million people worldwide, with cognitive dysfunction present in over 80% of patients. ...
15 hours ago
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Centuries-old medicine benefits heart failure patients, studies show
A low dose of digoxin ensures that people with heart failure are hospitalized and die less frequently. This emerges from three studies led by UMCG cardiologists Dirk Jan van Veldhuisen, Kevin Damman, and Peter van der Meer. ...
20 hours ago
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Trump promised cheaper drugs. Some prices dropped. Many others shot up
Since his second term started, President Donald Trump has announced, negotiated or floated a flurry of initiatives aimed at taming the excesses of the pharmaceutical industry.
10 hours ago
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New meta-analysis finds no increased risk to children's brain development from fathers' use of valproate
A comprehensive review of existing research shows no evidence that men's use of the anti-seizure medication valproate increases the risk of neurodevelopmental disorders—such as autism and ADHD—in their children.
11 hours ago
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Amputation rates on the rise for opioid-, non-opioid-related hospitalizations
Among opioid-related and non-opioid-related hospitalizations, amputation rates increased from 2016 to 2022, with greater increases seen among opioid-related hospitalizations nationally, according to a research letter published ...
13 hours ago
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Study shows use of obesity drugs alongside behavioral intervention is associated with reduced 'food noise'
New research presented at this year's European Congress on Obesity in Istanbul, Turkey, shows that use of obesity drugs alongside behavioral interventions leads to a larger drop in so‑called food noise than in those using ...
12 hours ago
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Are your meds and DNA a bad match? This test alerts clinicians
Differences in people's genes can affect how they respond to medications, including how well a drug works and the chances of side effects. About 1 in 10 of prescriptions given to patients outside the hospital don't work as ...
23 hours ago
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The magic of mushrooms: Psychedelic psilocybin shows promise for treating cocaine addiction
Cocaine addiction treatment has found a surprising new contender in the highly regulated substance psilocybin, a naturally occurring psychedelic compound found in mushroom species popularly known as magic mushrooms or shrooms. ...
HIV reveals more than 100 escape mutations against promising antibody therapies
Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily doses of antiretroviral drugs. In one recent clinical study of bNAbs identified ...
May 12, 2026
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AI joins the quest to find new treatments for rare diseases
Rare neuromuscular diseases often lack treatments because developing targeted drugs is slow, costly and risky for companies. A new approach using AI and stem cell models could finally shift the balance.
May 12, 2026
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Caffeine may influence the way the brain responds to touch
Many people begin each day with a steaming cup of joe to shake off the morning fog and jump-start their brain. Whether it's a shot of espresso or a frothy latte, that caffeine hit is famous for boosting alertness. However, ...
RNA therapy slows harmful heart remodeling after heart attack in clinical trial
Following an acute heart attack, pathological remodeling processes occur in the heart. One consequence is so-called left ventricular systolic dysfunction, in which the pumping function of the left ventricle is impaired. To ...
May 11, 2026
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That discount at the pharmacy counter may pack hidden costs
Next time you go to the pharmacy, you might be offered a coupon on your prescription drugs. While it may sound like a great deal—with the prospect of saving hundreds of dollars—the decision to accept it is complicated, especially ...
May 11, 2026
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A bird flu vaccine for humans is being trialed—here's how it works
The first ever avian influenza vaccine recently started trials in the US. This marks a milestone in the prevention of bird flu infections in humans.
May 11, 2026
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Delta‑8, delta‑9, THCA? What sets the different THC forms available in regulated cannabis products apart
Hemp products have exploded across the United States, even in the majority of states where recreational marijuana remains illegal. This surge came after the 2018 Farm Bill removed hemp from the Controlled Substances Act and ...
May 11, 2026
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Mouse tests show two antibiotics curb deadly S. maltophilia lung infections
Stenotrophomonas maltophilia (S. maltophilia) is a multidrug-resistant bacterium that can cause severe and life-threatening hemorrhagic pneumonia in individuals with weakened immune systems. Despite this, there are limited ...
May 11, 2026
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Attention to sex differences, relapse needed in early-stage studies of medication to treat alcohol use disorder
Early-stage studies of medications to treat high-risk alcohol use may be missing opportunities to identify potential therapeutic effects in certain populations, including women and people at risk for relapse, according to ...
May 11, 2026
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Treatment-resistant depression may yield to combinations of medications already in clinical use
Many people with major depressive disorder get no relief from current treatments. Newer combinations of existing medications might help, researchers report in JAMA Psychiatry.
May 10, 2026
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Nasal spray developed for prehospital emergency aid for ischemic stroke
A research team from Department of Pharmacology and Pharmacy at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), in collaboration with the InnoHK Advanced Biomedical Instrumentation Centre (ABIC), has developed ...
May 10, 2026
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New post-hoc analysis examined daily oral orforglipron in adults over 65 with obesity, with or without diabetes
A new analysis presented at the European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12–15 May) examined daily oral orforglipron treatment for the treatment of obesity, with or without diabetes, in users aged 65 years ...
May 10, 2026
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Gold-coated microneedles can detect subtleties in how liver and kidneys process drugs in real time
Scientists have taken a giant leap forward with the development of tiny microneedles designed to detect subtle but critical changes in how the liver and kidneys process therapeutic drugs. The experimental technology, under ...
Metformin's real power may be in the gut
For decades, physicians and scientists thought metformin, the leading type 2 diabetes medication taken by millions worldwide, mainly targets the liver to suppress glucose production. But a new Northwestern University study ...
May 8, 2026
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RFK Jr. launches plan to curb antidepressant 'overprescription'
A new federal initiative aims to curb "overprescribing" of psychiatric medications while emphasizing holistic care.
May 8, 2026
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