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Clinical pharmacology news

Freeze-dried platelet product slows swelling and bleeding in traumatic brain injuries

A freeze-dried blood product that could be stored for years on ambulances or in remote emergency departments is showing promise at treating traumatic brain injuries. The news comes from a mouse study done by researchers at ...

Paxlovid looked like a COVID game-changer, but in vaccinated adults the real story is far more complicated

The results of two clinical trials—led by the Upstream Lab at St. Michael's Hospital in Toronto and Oxford University, published in the New England Journal of Medicine—provide new evidence to consider when funding, prescribing, ...

New cellular target prevents hepatitis E infection

An international team of researchers has identified a promising new approach for treating infections with the Hepatitis E virus (HEV). At the center of the study is the drug Apilimod, which specifically blocks the entry of ...

US eases access to marijuana for medical use

The US government on Thursday made it easier for Americans to use cannabis for medical reasons by reclassifying the drug and enabling more research into its safety and efficacy.

Researchers explore new approach to multivirus drug development

Wanted: a cheap, multipotent treatment for viral infections. Must be able to handle new or unfamiliar strains, or (even better) a broad range of viruses—whatever comes along, in other words. Must be impervious to viral attempts ...

'Frankenproteins' offer hope in fighting cancer

Lab-created "frankenproteins" developed by a team of scientists at the University of Toronto Mississauga offer hope for safer and more effective cancer treatments in the future. The protein-based drugs being developed by ...

Molecular keyhole sheds light on pain and epilepsy

Researchers at VIB, VUB, and KU Leuven have identified a tiny binding site, a molecular "keyhole," in the TRPM3 ion channel, a crucial sensor in pain signaling. TRPM3 is also linked to rare neurodevelopmental disorders and ...

Trump signs order backing psychedelic research

Psychedelic drugs could soon play a larger role in mental health care. Over the weekend, President Donald Trump signed an executive order aimed at boosting federal research into substances like psilocybin, LSD and MDMA and ...