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Clinical pharmacology news
Antiviral ensitrelvir cuts risk of COVID-19 in household contacts by two-thirds, study finds
The antiviral drug ensitrelvir prevents infection in household contacts of COVID-19 patients when given within 72 hours after symptom onset in the index patient, according to a Phase III randomized controlled trial published ...
10 hours ago
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New targeted radiopharmaceutical therapy induces remission in pancreatic cancer model
A newly developed targeted radiopharmaceutical treatment can effectively slow tumor growth in pancreatic ductal adenocarcinoma (PDAC), according to new research published in the May issue of The Journal of Nuclear Medicine. ...
10 hours ago
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Single dose of psilocybin provides rapid relief from depression in double-blind study
A single dose of the psychedelic substance psilocybin can provide rapid relief from depressive symptoms—within just a few days. This is shown by the first randomized, double-blind study in Sweden of psilocybin for depression. ...
14 hours ago
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ADHD medications show dosage sweet spots, with little gain above limits
Researchers have identified the best dosage for each ADHD medication using data from thousands of people with the condition. The new study published in The Lancet Psychiatry provides the most comprehensive view of dosage ...
15 hours ago
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Improving the treatment of Lassa fever: First clinical trial with favipiravir shows promising results
The infectious disease Lassa fever can be fatal, and there is a lack of treatment options with proven efficacy. Researchers at the Bernhard Nocht Institute for Tropical Medicine (BNITM) and the University Medical Center Hamburg-Eppendorf ...
11 hours ago
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New obesity guidance urges dietitian-led care as GLP-1 drugs reshape treatment
Obesity and dietitian societies have joined forces to issue a new consensus statement on recommendations surrounding the use of obesity drugs for weight loss treatment. The consensus statement was presented at the European ...
5 hours ago
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Wegovy initiation may cut migraine drug use 8% in women after one year
A nationwide study from Denmark presented at the European Congress on Obesity (ECO2026) in Istanbul, Turkey, shows that use of semaglutide (Wegovy) for weight management is associated with a 7% reduction in the use of triptan-class ...
18 hours ago
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Study links use of new obesity drugs to reduction of asthma exacerbations and inhaler use
New research presented at the European Congress on Obesity in Istanbul, Turkey (May 12–15) shows the use of the new GLP-1 class of obesity drugs in people with asthma is associated with a 26% fall in the number of asthma ...
18 hours ago
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Researchers explore making behavioral health care more accessible
A study published in the American Journal of Managed Care explores how integrating behavioral health care into primary care can improve outcomes and be cost-effective for adults with depression, anxiety and chronic pain who ...
19 hours ago
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Viagra could hold key to halting Peyronie's disease
Combining two widely prescribed drug classes could provide the first effective treatment for early-stage Peyronie's disease, according to a new study published in The Journal of Sexual Medicine.
May 14, 2026
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Common NSAIDs in first trimester show no birth defect link, data suggest
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen and naproxen, taken during the first trimester of pregnancy are not associated with an increased risk of major birth defects, according to a new study published ...
May 14, 2026
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Which medicines can most affect driving? New tool estimates risk
Researchers from the SABIEN group at the ITACA Institute of the Universitat Politècnica de València (UPV), in collaboration with several partner institutions, have developed a new tool to estimate the risk of using medicines ...
May 14, 2026
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Not just an energy drink: National study finds kratom use is rising
A national study of kratom use in the U.S. found rising popularity among young adults, and it is linked to addiction and mental health issues, according to new research from the University of Michigan and Texas State University. ...
May 14, 2026
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Paired antiviral approach pushes SARS-CoV-2 toward near-complete loss of infectivity
A new study led by researchers at the University of Malaga proposes a new antiviral strategy against SARS-CoV-2—the virus responsible for causing COVID-19 disease—based on a treatment that combines two complementary approaches ...
May 14, 2026
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Cancer fatigue may ease within weeks as common stimulant shows benefit
A new meta-analysis in Journal of the National Comprehensive Cancer Network provides updated evidence that methylphenidate-type psychostimulants—a class of medication that increases dopamine and norepinephrine availability ...
May 14, 2026
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Semaglutide cuts BMI by 19% in treatment-resistant young adults with severe obesity, finds trial
A weekly dose of semaglutide (2.4 mg) leads to a clinically significant reduction in body mass index (BMI) and related health outcomes in young adults with severe obesity who are treatment resistant following hospital-based ...
May 14, 2026
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Peppermint oil can lower blood pressure, clinical trial finds
Daily doses of peppermint oil have been proved to lower blood pressure for patients with mildly high readings, new research has found. A team of University of Lancashire academics discovered a daily intake of 100 microliters ...
May 13, 2026
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15-year quest yields malaria compound that hits parasite at all major stages
A Portland State University-led research team has developed a novel chemical compound that shows promise for the treatment and prevention of malaria, one of the world's deadliest diseases. Malaria, a mosquito-borne infectious ...
May 13, 2026
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No refrigeration needed for next-gen malaria vaccine
Malaria is a deadly disease killing more than half a million people every year, but a new vaccine is showing promise as it not only offers long-lasting strong protection but also inhibits transmission of malaria by mosquitoes. ...
May 13, 2026
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Continuing tirzepatide at full dose helps preserve weight loss over 112 weeks
New research presented at the European Congress on Obesity (ECO 2026) in Istanbul, Turkey (12–15 May) and published in The Lancet shows that people who have lost weight using the maximum tolerated dose (MTD) of tirzepatide ...
May 13, 2026
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How one drug could lower dangerous bleeding in high-risk cesarean births
Giving tranexamic acid to women with placenta previa (when the placenta covers the cervical opening) undergoing cesarean birth leads to a significant yet modest reduction in severe bleeding after delivery with no evidence ...
May 13, 2026
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Popular weight loss and anti-inflammatory drugs may help prevent common heart rhythm disorder
Researchers at Ben-Gurion University of the Negev (BGU) have identified how two different classes of medication—the GLP-1 receptor agonist semaglutide and the anti-inflammatory drug colchicine—act on the heart to prevent ...
May 13, 2026
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Semaglutide may improve motivation with major depressive disorder
Treatment with semaglutide significantly improves measures of motivation in patients with major depressive disorder (MDD), according to a study published April 29 in JAMA Psychiatry.
May 13, 2026
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Alzheimer's therapeutic advancements may be financially inaccessible
A newly published study shows that while disease-modifying therapies (DMTs) may offer substantially greater health benefits than usual care, their real-world impact will depend on whether they are priced in ways that health ...
May 13, 2026
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Cannabis: It's medicine if you're rich enough, a crime if you're not
In Britain, whether cannabis is treated as medicine or a crime may depend less on medical need than on the ability to pay. In 2018, the UK government changed drug policy, allowing specialist doctors to prescribe cannabis-based ...
May 13, 2026
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