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Clinical pharmacology news
The magic of mushrooms: Psychedelic psilocybin shows promise for treating cocaine addiction
Cocaine addiction treatment has found a surprising new contender in the highly regulated substance psilocybin, a naturally occurring psychedelic compound found in mushroom species popularly known as magic mushrooms or shrooms. ...
11 minutes ago
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HIV reveals more than 100 escape mutations against promising antibody therapies
Broadly neutralizing antibodies (bNAbs) are among the most promising new treatments for HIV, offering the potential to forego traditional daily doses of antiretroviral drugs. In one recent clinical study of bNAbs identified ...
4 hours ago
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AI joins the quest to find new treatments for rare diseases
Rare neuromuscular diseases often lack treatments because developing targeted drugs is slow, costly and risky for companies. A new approach using AI and stem cell models could finally shift the balance.
4 hours ago
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RNA therapy slows harmful heart remodeling after heart attack in clinical trial
Following an acute heart attack, pathological remodeling processes occur in the heart. One consequence is so-called left ventricular systolic dysfunction, in which the pumping function of the left ventricle is impaired. To ...
11 hours ago
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Caffeine may influence the way the brain responds to touch
Many people begin each day with a steaming cup of joe to shake off the morning fog and jump-start their brain. Whether it's a shot of espresso or a frothy latte, that caffeine hit is famous for boosting alertness. However, ...
That discount at the pharmacy counter may pack hidden costs
Next time you go to the pharmacy, you might be offered a coupon on your prescription drugs. While it may sound like a great deal—with the prospect of saving hundreds of dollars—the decision to accept it is complicated, especially ...
10 hours ago
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A bird flu vaccine for humans is being trialed—here's how it works
The first ever avian influenza vaccine recently started trials in the US. This marks a milestone in the prevention of bird flu infections in humans.
14 hours ago
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Delta‑8, delta‑9, THCA? What sets the different THC forms available in regulated cannabis products apart
Hemp products have exploded across the United States, even in the majority of states where recreational marijuana remains illegal. This surge came after the 2018 Farm Bill removed hemp from the Controlled Substances Act and ...
18 hours ago
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Mouse tests show two antibiotics curb deadly S. maltophilia lung infections
Stenotrophomonas maltophilia (S. maltophilia) is a multidrug-resistant bacterium that can cause severe and life-threatening hemorrhagic pneumonia in individuals with weakened immune systems. Despite this, there are limited ...
19 hours ago
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Attention to sex differences, relapse needed in early-stage studies of medication to treat alcohol use disorder
Early-stage studies of medications to treat high-risk alcohol use may be missing opportunities to identify potential therapeutic effects in certain populations, including women and people at risk for relapse, according to ...
22 hours ago
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Treatment-resistant depression may yield to combinations of medications already in clinical use
Many people with major depressive disorder get no relief from current treatments. Newer combinations of existing medications might help, researchers report in JAMA Psychiatry.
May 10, 2026
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Nasal spray developed for prehospital emergency aid for ischemic stroke
A research team from Department of Pharmacology and Pharmacy at the LKS Faculty of Medicine, the University of Hong Kong (HKUMed), in collaboration with the InnoHK Advanced Biomedical Instrumentation Centre (ABIC), has developed ...
May 10, 2026
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New post-hoc analysis examined daily oral orforglipron in adults over 65 with obesity, with or without diabetes
A new analysis presented at the European Congress on Obesity (ECO 2026, Istanbul, Turkey, 12–15 May) examined daily oral orforglipron treatment for the treatment of obesity, with or without diabetes, in users aged 65 years ...
May 10, 2026
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Gold-coated microneedles can detect subtleties in how liver and kidneys process drugs in real time
Scientists have taken a giant leap forward with the development of tiny microneedles designed to detect subtle but critical changes in how the liver and kidneys process therapeutic drugs. The experimental technology, under ...
Metformin's real power may be in the gut
For decades, physicians and scientists thought metformin, the leading type 2 diabetes medication taken by millions worldwide, mainly targets the liver to suppress glucose production. But a new Northwestern University study ...
May 8, 2026
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RFK Jr. launches plan to curb antidepressant 'overprescription'
A new federal initiative aims to curb "overprescribing" of psychiatric medications while emphasizing holistic care.
May 8, 2026
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Technology receives FDA approval for breast cancer treatment
More than a decade ago, Yale chemist Craig Crews founded a biotechnology company in New Haven based on his pioneering research into PROTACs (or PROteolysis TArgeting Chimera), a technology that treats certain types of cancer ...
May 8, 2026
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Higher-dose ivermectin no better than standard dose for severe scabies
For adults with severe scabies, higher-dose ivermectin plus permethrin is not superior to standard-dose ivermectin plus permethrin, according to a study published in the New England Journal of Medicine.
May 8, 2026
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Garlic-derived compound shows potential to improve muscle health during aging
Can a compound derived from a common kitchen ingredient help support muscle health during aging? A new study suggests it can. The study reveals that S-1-propenyl-L-cysteine (S1PC), a bioactive compound found in aged garlic ...
May 7, 2026
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Leukemia stem cells cause treatments to fail, but findings open new avenues to overcome resistance
Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have deciphered a key mechanism that contributes to treatment failure in acute myeloid leukemia (AML). They show that there are ...
May 7, 2026
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Key magic mushroom ingredient makes fish less aggressive and lazier
More than 200 mushrooms—primarily those belonging to a genus of gilled mushrooms called Psilocybe—contain the psychoactive compound psilocybin. In the brain of mammals, this chemical can bind to serotonin receptors and influence ...
May 7, 2026
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Scientists take crucial step in developing world's first measles treatment
Scientists at La Jolla Institute for Immunology (LJI) are the first in the world to characterize human antibodies capable of neutralizing measles virus. These antibodies bind to key sites on measles virus and prevent the ...
May 7, 2026
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FDA approves Auvelity for Alzheimer's disease-related agitation
The U.S. Food and Drug Administration has approved the expanded use of Axsome Therapeutics' Auvelity (dextromethorphan hydrobromide and bupropion hydrochloride) extended-release tablets to treat adults with agitation associated ...
May 7, 2026
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New research raises concerns about safety of higher-THC medicinal cannabis products in Australia
New Monash University research has found that more than half of all adverse events reported to Australia's medicines regulator involving medicinal cannabis were linked to higher-THC products, with psychiatric disorders the ...
May 7, 2026
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Can peptide injections help people recover from injuries? Here's what you need to know
It's tough to avoid the current hype about the health benefits of injecting peptides. Although these substances—essentially, synthetic bits of protein in solution—have long made the rounds in the fitness world, their popularity ...
May 7, 2026
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