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Clinical pharmacology news
Aspirin may unmask silent bladder cancer by triggering bleeding
The presence of blood cells in urine is a sign of bladder cancer. Because aspirin blocks platelets from forming harmful blood clots, the medication can cause mild bleeding or worsen existing bleeding in the urinary tract. ...
5 hours ago
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Ranking high blood pressure drug combinations from most to least tolerated
The Global Hypertension Report by the World Health Organization (WHO) revealed that 1.4 billion people were living with hypertension in 2024. Yet, only a little over one in five of those diagnosed have it under control, whether ...
Existing drug enhances muscle repair during GLP-1 weight-loss treatment in mice
Millions of Americans are currently taking GLP-1 medications such as Ozempic or Wegovy for weight loss. But along with the fat, many are quietly losing something else: muscle. Unlike fat, muscle doesn't return quickly, and ...
14 hours ago
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Combination of five mRNAs mitigates heart failure after myocardial infarction, research reveals
A heart attack is far from an isolated, acute event. The consequences of an attack can cause serious and lasting damage, including heart failure. However, researchers and clinicians have been unable to determine a standardized ...
12 hours ago
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Serious infection risks linked to targeted cancer therapies
A major real-world study by University of California, Irvine pharmacy researchers has found serious blood-related side effects associated with antibody-drug conjugates, an increasingly important class of targeted cancer therapies. ...
12 hours ago
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Acetaminophen reaffirmed as first-line medication for treating pain and fever during pregnancy
Acetaminophen remains the recommended first-line medication to treat pain and fever during pregnancy, according to an updated statement from the Society for Maternal-Fetal Medicine (SMFM). A comprehensive review of the available ...
16 hours ago
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GLP-1 agonists linked to significantly lower long-term risk of knee replacement
GLP-1 receptor agonist drugs, used for the treatment of diabetes—and more recently, weight loss—are associated with a significantly lower long-term risk of knee replacement surgery as a result of osteoarthritis, finds an ...
14 hours ago
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Understanding the complex relationship between opioids and suicidal ideation in spinal cord injury survivors
For the roughly 300,000 Americans living with a spinal cord injury (SCI), chronic pain is often a part of daily life, and—for many—opioids are prescribed to combat it. In addition to the serious physical considerations, mental ...
16 hours ago
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GLP‑1 drugs like Ozempic show promise for more than weight loss, but what's science vs. hype?
You've probably heard of Ozempic or Wegovy. These are the injectable drugs that have become household names for weight loss and diabetes.
18 hours ago
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NASA medication storage protocols evaluated
Southwest Research Institute evaluated NASA's medication handling practices, which currently call for removing medications from their original packaging and storing them in resealable plastic bags. Although this allows astronauts ...
20 hours ago
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First‑in‑human study tests gamitrinib designed to disrupt cancer cells' energy systems
Cancer cells need large amounts of energy to survive and multiply. To produce that energy, they rely on structures inside the cell called mitochondria, often described as the cell's "powerhouse." Unlike healthy cells, cancer ...
22 hours ago
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GLP-1 use linked to lower breast cancer incidence in large cohort study
A retrospective analysis of more than 110,000 women between the ages of 45 and 80 found that those who took GLP-1 medications were about 30% less likely to develop breast cancer than those who did not take GLP-1 medications, ...
Jun 2, 2026
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Indigenous-led project sets new benchmarks for ethical cultural medicine research
Traditional Knowledge has supported health and well-being practices for thousands of years using medicinal plants and cultural medicines. But how can that knowledge be applied appropriately for use in scientific drug discovery?
Jun 2, 2026
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Newest medicines work just as well at half dosage for stable psoriasis, new study finds
Three-quarters of people who respond well to the newest types of biologics for psoriasis can safely reduce their dosage, often even by half. These medications then work just as effectively, according to a study led by Radboud ...
Jun 1, 2026
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Global rules could cut costs and speed access to GLP-1 drugs
FDA-approved carbon copies of brand-name drugs with expired patents—over the last 30 years, these generic drugs have saved trillions of dollars for hundreds of millions of people.
Jun 1, 2026
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'We need to act now': Race to develop Ebola vaccine heats up
Several non-profit organizations announced Monday they are ramping up efforts to rapidly develop a vaccine for the rare strain of Ebola driving a deadly outbreak in the Democratic Republic of Congo.
Jun 1, 2026
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Commonly prescribed medication for sleep problems raises alarm bells
Amid growing concern about the widespread off-label use of sedative medications for sleep problems, Flinders University researchers have led a world-first clinical trial examining how a commonly prescribed "sleeping pill" ...
Jun 1, 2026
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Ibuprofen for joint pain: What you really need to know
Millions of people in the UK suffer from joint pain and arthritis. But with long wait times for scans, specialist appointments, physiotherapy, and joint replacement surgery, many people turn to over-the-counter medicines, ...
Jun 1, 2026
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The dangers of legitimizing doping
In Las Vegas May 2026, athletes compete in an international sporting event that explicitly allows them to use performance-enhancing drugs (PEDs). The Enhanced Games openly encourages competitors to use substances banned in ...
Jun 1, 2026
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One-time gene editing treatment lowers 'bad' cholesterol by up to 62%
Patients in London have received a pioneering new gene editing therapy that lowers "bad" cholesterol after a single infusion, as part of a study involving UCL scientists.
May 31, 2026
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Influencers are promoting dangerous peptides on social media, and regulators are struggling to keep up
Once confined to niche bodybuilding forums and hardcore gyms, unproven injectable peptides are now being openly marketed online to the average gym-goer by social media influencers—and regulators struggling to keep up.
May 31, 2026
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One inhibitor, opposite outcome: How a double-target effect could reshape ferroptosis therapies
Switching off an enzyme that plays an important role in sugar metabolism, glycolysis, would normally be expected to cause serious problems for cells. Surprisingly, the opposite is also true: Cells can become highly resistant ...
May 30, 2026
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Tezepelumab helps severe asthma patients reduce oral steroids over 28 weeks
New results from the Phase III SUNRISE clinical trial show that tezepelumab significantly reduced the need for long-term oral corticosteroid use in adults with severe oral corticosteroid-dependent asthma while maintaining ...
May 30, 2026
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Cannabidiol significantly reduces chronic pain for those with nerve damage
A new study by researchers at the University of Sydney has shown that taking cannabidiol (CBD) can significantly reduce chronic neuropathic pain in those suffering from it. The findings of the randomized placebo-controlled ...
May 29, 2026
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