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Neuroscience

A molecular atlas of the hippocampus: Mapping RNAs and proteins at synaptic resolution

Researchers at the Max Planck Institute for Brain Research have mapped the molecular landscape of the mouse hippocampus, a region central to learning and memory. By combining RNA and protein profiling with advanced methods ...

Medications

Unproven stroke treatment is no more effective than placebo, clinical trial finds

The first international trial of an unproven stroke treatment available in the U.S. has concluded that, while harmless, "perispinal" etanercept—injected into the spinal area—is no more effective than an inactive dummy ...

Diseases, Conditions, Syndromes

Hidden brain waves may serve as triggers for post-seizure wandering

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the German Center for Neurodegenerative ...

Genetics

CRISPR approach offers hope for severe childhood brain disorder

When brain development gets off to a bad start, the consequences are lifelong. One example is a condition called SCN2A haploinsufficiency, in which children are born with just one functioning copy of the SCN2A gene—instead ...

Neuroscience

Scientists explore how TB bacteria enter the brain

Researchers at the Francis Crick Institute have shown how the bacteria causing tuberculosis (TB) directly cross the brain's protective barrier, causing meningitis, a very severe form of the disease that occurs in 1%–10% ...

Neuroscience

Aphasia can be the first sign of stroke

Aphasia is a disorder that affects a person's ability to retrieve language. It's as if their brain's word cabinet has fallen over and mixed their words around, resulting in varying levels and forms of impairment, including ...

Neuroscience

Weight loss linked to nerve cells in the brain

Semaglutide belongs to a group of drugs called GLP-1R agonists and has been shown to effectively reduce food intake and body weight. The drug is already well established as part of the treatment for obesity and type 2 diabetes, ...

Neuroscience

Muscle quality may hold clues to early cognitive decline

Over the past decade, much research has focused on the connection between skeletal muscle health and cognitive disorders. Scientists have found that sarcopenia, a geriatric syndrome characterized by progressive loss of skeletal ...

Neuroscience

More can be done to prevent common type of stroke, say experts

Subarachnoid hemorrhage, the third most common type of stroke, accounting for 5–10% of all cases, could be drastically reduced worldwide through health and lifestyle changes, according to NZ, Australian and international ...

Genetics

Tiny genetic switch found to control brain balance and behavior

Researchers at the Institute for Basic Science (IBS) have identified a remarkably small but critical piece of genetic code that helps determine how brain cells connect, communicate, and function. The discovery not only deepens ...

Neuroscience

Electrical stimulation offers hope for treating spinal injuries

A grid of electrodes placed on the backs of study participants delivered enough low-voltage electrical stimulation through the skin to change the short-term function of spinal cord neurons, a study led by UT Southwestern ...