Lymphoma survivors at risk for developing chronic kidney disease

Lymphoma survivors at risk for developing chronic kidney disease

(HealthDay)—Lymphoma survivors are at substantial long-term risk for chronic kidney disease (CKD) development, according to a study published online July 11 in Leukemia & Lymphoma.

Sanjal H. Desai, M.D., from the Medstar Washington Hospital Center in Washington, D.C., and colleagues describe patterns of long-term CKD in lymphoma survivors. At diagnosis and years 1, 2, 5, and 10, (GFR) was recorded.

The researchers found that among 397 patients (median age, 55.3 years; 54 percent male; 60 percent African-American), 42 percent had hypertension, 15 percent had , 13 percent had hyperuricemia, 86 percent received chemotherapy, and 14 percent had baseline CKD. Just under one-third of patients (31 percent) developed CKD within 10 years of lymphoma diagnosis. There was a significant increase noted in the probability of CKD development with time (23 percent at year 1 increased to 41 percent at year 10). The investigators observed a decline in GFR of 4.6 mL/min/per year. CKD was predicted by age, hypertension, hyperuricemia, and diabetes (in ).

"These findings underscore the need to monitor renal function in long-term lymphoma survivors and lay foundation for future prospective studies to define strategies to prevent CKD in lymphoma survivors," the authors write.

More information: Abstract/Full Text (subscription or payment may be required)

Copyright © 2020 HealthDay. All rights reserved.

Citation: Lymphoma survivors at risk for developing chronic kidney disease (2020, July 20) retrieved 28 March 2024 from https://medicalxpress.com/news/2020-07-lymphoma-survivors-chronic-kidney-disease.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Explore further

Factors predict low BMD in pediatric blood cancer survivors

10 shares

Feedback to editors