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Obstetrics & gynecology news

New stem cell models reveal how earliest human placenta structures take shape

The placenta is essential for a healthy pregnancy, but the earliest steps of its formation have been hidden from scientific view. Now Columbia researchers led by Mijo Simunovic have created lab-grown organoids that reconstruct ...

Blood RNA signal may reveal ovarian cancer precursors before invasive disease develops

Hoag researchers have discovered a molecular warning signal in the blood that identifies serous tubal intraepithelial carcinoma (STIC), an early, precancerous stage of high-grade serous ovarian cancer (HGSOC). This advance ...

Q&A: How do infections get past the placenta's defenses?

For nine months, the placenta is the primary support system of the fetus, providing both nourishment and protection. Within hours of birth, it is usually discarded as medical waste. But this organ carries clues to the child's ...

Cervical cancer cases and deaths forecast to rise

Global cervical cancer cases and deaths could rise by 20.2% and 39.3%, respectively, by 2050, according to a modeling study published in Nature Medicine. The findings suggest that the burden of cervical cancer will remain ...

How pregnancy itself drives deadly hepatitis E outcomes

Researchers have uncovered a biological mechanism that helps explain why hepatitis E virus infections can be especially severe—and often fatal—during pregnancy, finding that normal pregnancy-related hormonal changes inadvertently ...

HRT linked to lower dementia risk in large UK study

Hormone replacement therapy (HRT) may reduce the risk of dementia, particularly for certain groups of women—according to a study from the University of East Anglia and the University of Exeter.

High folic acid in pregnancy linked to early bleeding risk

Women taking high-dose folic acid supplements during early pregnancy may face an increased risk of vaginal bleeding, according to new research from Flinders University and collaborating institutions that raises important ...

New rapid test could transform iron treatment worldwide

Iron deficiency is one of the world's most common nutritional disorders, affecting millions of women and children globally. Yet diagnosing it remains difficult in many low-resource settings, where access to laboratories and ...

Novel stem cell platform improves study of endometriosis

Scientists led by Julie Kim, Ph.D., the Susy Y. Hung Research Professor of obstetrics and gynecology in the Division of Reproductive Science in Medicine, have developed a novel stem cell platform that provides a new way to ...

Specialized imaging reveals hormone-driven brain changes

A new study from the University of Delaware shows that fluctuations in estrogen influence the brain, helping reshape connections between neurons. Researchers showed that a specialized imaging technique called magnetic resonance ...