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Overweight & Obesity news
Cardiology
Waist-to-height ratio outperforms BMI in predicting heart disease risk
The ratio of a person's waist measurement compared to their height is more reliable than body mass index (BMI) at predicting heart disease risk, according to new research from UPMC and University of Pittsburgh physician-scientists.
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Genes associated with obesity shared across ancestries, researchers find
Obesity is a global epidemic affecting millions of people every day and is associated with comorbidities ranging from heart disease and type 2 diabetes to osteoarthritis and social stigma. While lifestyle factors, like diet ...
Oct 30, 2025
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Novo Nordisk launches bidding war with Pfizer for obesity drugmaker Metsera
Danish pharmaceutical giant Novo Nordisk, maker of weight-loss drugs Ozempic and Wegovy, announced Thursday an unsolicited bid to acquire obesity treatment maker Metsera, topping an offer from US rival Pfizer which called ...
Oct 30, 2025
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GLP-1 drugs effective for weight loss, but more independent studies needed
Three new Cochrane reviews find evidence that GLP-1 drugs result in clinically meaningful weight loss, but industry-funded studies raise questions. The reviews were commissioned by the World Health Organization (WHO) to inform ...
Oct 29, 2025
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Combination of obesity and poor sleep increases risk of multiple chronic diseases
People with poor sleep and obesity have a much higher risk of multimorbidity—having two or more chronic diseases at the same time—University of Queensland researchers have found.
Oct 29, 2025
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Weight loss alone not enough to boost men's fertility
How men lose weight could affect their chances of having a baby, with new research from the University of Adelaide revealing healthy lifestyle behaviors seem more beneficial for improving fertility than weight loss itself.
Oct 28, 2025
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Genetic variants can simultaneously increase BMI and lower cholesterol risk
Individuals with a genetic profile that puts them at risk of obesity may not necessarily be at risk of having high cholesterol, UTHealth Houston researchers discovered.
Oct 28, 2025
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Global survey reveals obesity hidden in normal BMI contributing to metabolic disorders
A multinational team of researchers has discovered that over 20% of adults with a normal BMI range experience levels of abdominal obesity that puts them at higher risk of hypertension, diabetes, high total cholesterol, and ...
Bariatric surgery in a pill bottle
More than 37 million Americans have type 2 diabetes, a chronic disorder affecting the body's ability to regulate and use sugar. According to the CDC, it's the country's seventh leading cause of death. Type 2 diabetes can ...
Oct 24, 2025
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Discovery shakes 60 years of certainty about fat metabolism
Scientists have known hormone-sensitive lipase (HSL) as the enzyme that releases energy stored in our fat. Yet patients born without this protein do not become obese: on the contrary, they lose their adipose tissue, developing ...
Oct 23, 2025
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Obesity drugs regulate neural systems to curb appetite, research reveals
A recent Northwestern Medicine study has identified novel neural circuits modulated by the diabetes and obesity-management drugs semaglutide and tirzepatide that help suppress appetite, according to findings published in ...
Oct 23, 2025
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The first child-specific body scan charts could enable physicians to assess obesity risk
A Concordia-led research team has created one of the first reference charts showing how children's adipose (fat) and muscle levels change with age and sex—a breakthrough that could help identify young people at risk for ...
Oct 23, 2025
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Mitochondrial potassium channels regulate heat production in brown adipose tissue, paving path for new obesity therapies
A study conducted by researchers at the Center for Redox Processes in Biomedicine (Redoxoma) has shown that ATP-sensitive mitochondrial potassium channels (MitoKATP) are involved in both the development of brown fat cells ...
Oct 22, 2025
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Semaglutide helps heart regardless of how much weight lost, study reveals
Anti-obesity medication semaglutide may help to prevent heart attacks and other major cardiac events regardless of how much weight people lose while taking the drug, according to a new study led by a UCL researcher.
Oct 22, 2025
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A year of dieting with non-sugar sweeteners shows weight loss can stay lost
Researchers at Maastricht University and the University of Copenhagen report that incorporating sweeteners and sweetness enhancers within a healthy, sugar-reduced diet supported one-year weight loss maintenance and coincided ...
Gene deficiency that causes obesity also protects from heart disease, finds new study
Deficiency of the gene melanocortin 4 receptor (MC4R) is linked with obesity among adults. A recent study has found that the same deficiency also leads to surprising outcomes such as reduced risk of heart disease, lower cholesterol, ...
Early natural menopause linked with higher risk of metabolic syndrome
The prevalence of metabolic syndrome, a dangerous and potentially deadly condition, increases with menopause. That's the result of decreasing estrogen that protects against these metabolic conditions. A new study not only ...
Oct 21, 2025
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In Mississippi, Medicaid coverage of weight loss drugs fails to catch on
In a state where the obesity rate ranks among the highest in the country, many health providers were thrilled when Mississippi Medicaid in 2023 began covering GLP-1s for people 12 and older. Only 13 states cover the drugs ...
Oct 21, 2025
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Study sheds light on the role of genetics in the body weight
The obesity rate has been steadily climbing and so have scientific efforts to understand why. A new study, published in Nature Communications, takes a closer look at the genes behind body weight and how they might point toward ...
Oct 20, 2025
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Brain scans may predict future weight gain in people with mental disorders
With a simple standard MRI scan of the brain, it may soon be possible to predict which people with mental illnesses will gain weight after their initial diagnosis—thereby increasing their risk of physical diseases—and ...
Oct 20, 2025
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New blood-based biomarkers could help predict bariatric surgery outcomes in teens
A USC-led team has developed an innovative way to predict blood pressure outcomes after bariatric surgery that outperforms the current standard practice. In 108 adolescents who underwent bariatric surgery, the researchers ...
Oct 20, 2025
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New weight loss pill aims to bridge gap in obesity treatments
An innovative new pill could soon offer a new and affordable weight management treatment, following a successful clinical trial involving University of Bristol researchers. The results are published in a paper titled "A randomized, ...
Oct 20, 2025
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Obesity-related cancer rising among both younger and older adults worldwide, study finds
A surveillance study compared international cancer incidence trends of 13 cancer types in younger and older adults.
Oct 20, 2025
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Mortality down with GLP-1 receptor agonist use in T2D, especially in those with OSA
Patients with type 2 diabetes mellitus (T2DM) prescribed glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have significantly lower one-year mortality, especially those also diagnosed with obstructive sleep apnea (OSA), ...
Oct 20, 2025
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