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Parkinson's & Movement disorders news
Neuroscience
Q&A: New diagnostics and treatments for ALS and dementia—a key protein may point the way
The two neurodegenerative diseases could not appear more different. Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig's disease, affects the muscles, ultimately paralyzing people with the disorder. Frontotemporal ...
Nov 27, 2025
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Neuroscience
Protein ubiquilin-2 found to promote Parkinson's-linked α-synuclein aggregation
Parkinson's disease (PD) is an age-related, progressive neurodegenerative disorder. The hallmark of PD pathogenesis is the Lewy bodies (LBs) that accumulate in neurons in the substantia nigra region of the brain, damaging ...
Nov 26, 2025
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Brain markers could yield early clues into Parkinson's disease
Parkinson's disease affects more than 1.1 million people in the United States, progressively damaging the brain cells that control movement. By the time symptoms like tremors appear, patients have already lost around half ...
Nov 25, 2025
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'Zap-and-freeze' technique successfully used to watch human brain cell communication
Researchers at Johns Hopkins Medicine say they have used a "zap-and-freeze" technology to watch hard-to-see brain cell communications in living brain tissue from mice and humans.
Nov 24, 2025
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Researchers reveal progressive, regional brain changes in Parkinson's disease
New research has revealed that Parkinson's disease causes significant and progressive changes to blood vessels in the brain, changing our understanding of the disease which may lead to new treatment methods.
Nov 24, 2025
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Untreated sleep apnea raises risk of Parkinson's, study finds
New research reveals that people with untreated obstructive sleep apnea have a higher risk of developing Parkinson's disease. However, they can significantly reduce the risk by improving the quality of their sleep by using ...
Nov 24, 2025
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Pause and rewind: How the brain keeps time to control action
Whether speaking or swinging a bat, precise and adaptable timing of movement is essential for everyday behavior. Although we do not have sensory organs like eyes or a nose to sense time, we can keep time and control the timing ...
Nov 19, 2025
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Evidence builds for disrupted mitochondria as cause of Parkinson's
For decades, scientists have known that mitochondria, which produce energy inside our cells, malfunction in Parkinson's disease. But a critical question remained: do the failing mitochondria cause Parkinson's, or do they ...
Nov 17, 2025
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Next-generation microbiome medicine may transform Parkinson's treatment
The age-old advice to "trust your gut" could soon take on new meaning for people diagnosed with Parkinson's disease, thanks to a creative feat of bioengineering by researchers in the University of Georgia's College of Veterinary ...
Nov 17, 2025
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What polymers can teach us about curing Alzheimer's disease
Researchers from Tokyo Metropolitan University have applied ideas from polymer physics to illuminate the mechanism behind a key pathology in Alzheimer's disease, the formation of fibrils of tau proteins. They showed that ...
Nov 17, 2025
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New genetic test targets elusive cause of rare movement disorder
Scientists at Brigham and Women's Hospital and Harvard Medical School have developed a targeted genetic test to improve diagnosis for X-linked dystonia-parkinsonism (XDP), a rare and disabling movement disorder that affects ...
Nov 15, 2025
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Drug candidate slows motor neuron disease progression and preserves muscle function in preclinical study
A drug candidate found to protect nerve cells damaged by motor neuron disease (MND), could offer new hope to people living with the devastating condition.
Nov 11, 2025
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Removing toxic proteins before they can damage motor neurons
University of Wollongong (UOW) scientists have developed a breakthrough therapy that clears toxic proteins from nerve cells—a discovery that advances the work of the late Professor Justin Yerbury and could transform the ...
Nov 10, 2025
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Q&A: New tech helps Parkinson's patients who have trouble walking
Researchers at UC San Francisco have developed a new way to improve walking for patients with Parkinson's disease using deep brain stimulation and artificial intelligence.
Nov 9, 2025
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Shared synaptic mechanism for Alzheimer's and Parkinson's disease unlocks new treatment possibilities
Parkinson's and Alzheimer's diseases are the two most common neurodegenerative disorders, affecting millions of people worldwide. Published in the Journal of Neuroscience, new research from the Okinawa Institute of Science ...
Nov 5, 2025
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How brain lipids help neurons communicate and protect themselves
A University of Alberta research team has discovered a new function for brain molecules known as gangliosides, offering potential new targets for the treatment of Huntington's and other genetic neurological diseases.
Nov 5, 2025
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Slowed by sound: Mouse model of Parkinson's disease shows noise affects movement
In the development of Parkinson's disease, it may not be a good idea to turn the amp to 11. High-volume noise exposure produced motor deficits in a mouse model of early-stage Parkinson's disease, and established a link between ...
Nov 4, 2025
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The right dose for the brain: Selenomethionine's role in protecting dopaminergic neurons
Dopamine is often called the brain's "motivation molecule," but for me, it represents something deeper, a window into how fragile our neurons can be. The cells that produce dopamine, known as dopaminergic neurons, are among ...
Detailed map of the developing human brain opens new pathways for Parkinson's treatment
Scientists from Duke-NUS Medical School and their collaborators have created one of the most comprehensive single cell maps of the developing human brain. The atlas captures nearly every cell type, their genetic fingerprints, ...
Nov 3, 2025
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Personalized care can ease Parkinson's pain
Every 27 minutes, someone in Australia is diagnosed with Parkinson's disease. Best known for its tremors, movement and balance issues, it also brings another, often overlooked burden—persistent pain.
Nov 3, 2025
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New electrical signature of Parkinson's disease identified
What happens in the brain when a person experiences the characteristic movement symptoms of Parkinson's disease? Researchers around the world are seeking answers through various approaches. One of these builds on a treatment ...
Oct 30, 2025
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A newly-discovered mechanism could contribute to the therapeutic effects of deep brain stimulation
Deep brain stimulation (DBS) is a surgical procedure that entails the delivery of high-frequency electrical impulses to specific regions of the brain, via surgically implanted electrodes. While it requires an invasive surgical ...
Common genetic causes across motor neuron diseases identified
Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct. However, an analysis led by investigators ...
Oct 29, 2025
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FDA-approved focused ultrasound treatment for essential tremor now in use as primary treatment for Parkinson's
Barely an hour after being wheeled into a clinical space at Oregon Health & Science University on Aug. 27, an Arkansas woman emerged with vastly improved symptoms of the Parkinson's disease that had plagued her for the past ...
Oct 29, 2025
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Q&A: New drug being reviewed by the FDA to treat Parkinson's disease
The U.S. Food and Drug Administration is reviewing a new Parkinson's disease drug called tavapadon that could give people with the disease more control over their movements.
Oct 29, 2025
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