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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

Skin swabs could detect Parkinson's disease up to seven years before symptoms appear

A new study has revealed promising progress in developing a non-invasive sampling method to detect early signs of Parkinson's disease—up to seven years before motor symptoms appear—by analyzing the chemical makeup of ...

Medications

Weekly injection offers steady Parkinson's medication, reducing need for daily pills

A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Neuroscience

How Parkinson's disease affects emotion recognition of voices

A new study in Neurodegenerative Diseases looks closely at how Parkinson's disease can affect something as everyday and essential as recognizing emotion in someone's voice. The research suggests that both the side of the ...

Parkinson's & Movement disorders

Mouth and gut bacteria linked to brain changes in Parkinson's disease

Scientists have discovered a link between bacteria in the mouth and gut and the progression of cognitive decline in Parkinson's disease. Specific changes in these bacteria, known as the microbiome, have been associated with ...

Medications

Asthma drug could help to treat a rare neurological disorder

The asthma medication theophylline is a suitable drug for treating the rare neurological disorder ADCY5-related dyskinesia, according to a new study by Martin Luther University Halle-Wittenberg (MLU), which was published ...

Parkinson's & Movement disorders

Study reveals racial disparities in Huntington's disease diagnoses

Research led by UCLA Health reveals that Black patients with Huntington's disease in the U.S. and Canada received their diagnoses, on average, one year later compared to white patients after symptoms first appear.

Parkinson's & Movement disorders

Improving measurement of Parkinson's disease severity with AI

Despite recent advancements in the treatment of Parkinson's disease, it remains a challenge to accurately measure the progression of symptoms in this neurological disorder. While noticeable symptoms like tremors, stiffness ...

Parkinson's & Movement disorders

Could AI be the answer to early Parkinson's disease diagnoses?

Parkinson's disease is a significant health concern with profound impacts on individuals, the health care system and broader society. The current diagnosis model, which heavily relies on a medical professional interpreting ...

Neuroscience

Cracking the code for cerebellar movement disorders

The cerebellum is a region of the brain that helps us refine our movements and learn new motor skills. Patients and mouse models experience many kinds of abnormal movements when their cerebellum is damaged. They can have ...

Neuroscience

New cellular mechanisms in Parkinson's disease discovered

A pair of recent studies led by Joseph Mazzulli, Ph.D., associate professor in The Ken & Ruth Davee Department of Neurology's Division of Movement Disorders, have uncovered previously unknown cellular mechanisms involved ...

Parkinson's & Movement disorders

Brain connectivity on MRI predicts Parkinson's disease progression

The structural and functional organization of the brain as shown on MRI can predict the progression of brain atrophy in patients with early-stage, mild Parkinson's disease, according to a study published today in Radiology, ...

Alzheimer's disease & dementia

Diagnosing essential tremor after death helps families learn risk

A statistical tool designed to analyze 11 characteristics of postmortem brains reliably diagnosed a common neurodegenerative disease known as essential tremor (ET), a study led by researchers at UT Southwestern Medical Center ...

Parkinson's & Movement disorders

Blood test could predict Parkinson's seven years before symptoms

A team of researchers, led by scientists at UCL and University Medical Center Goettingen, has developed a simple blood test that uses artificial intelligence (AI) to predict Parkinson's up to seven years before the onset ...

Parkinson's & Movement disorders

AI helps uncover early cell changes in ALS progression

New research from the University of St Andrews and the University of Copenhagen has harnessed the power of AI to generate new insights into the progression of ALS.

Alzheimer's disease & dementia

Sulfur metabolites linked to neurodegenerative diseases

Neurodegenerative diseases (NDDs), which have no known cures and elusive causes, result in irreversible damage to the brain and nervous system. Research into these diseases typically focuses on the brain, but mouse studies ...

Parkinson's & Movement disorders

Smartwatches offer window into Parkinson's disease progression

Ubiquitous wearable technologies, like smartwatches, could help researchers better understand progressive neurological disorders like Parkinson's disease and speed up the approval of new therapies, a critical need given that ...