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Parkinson's & Movement disorders news

Neuroscience

New electrical signature of Parkinson's disease identified

What happens in the brain when a person experiences the characteristic movement symptoms of Parkinson's disease? Researchers around the world are seeking answers through various approaches. One of these builds on a treatment ...

Neuroscience

A newly-discovered mechanism could contribute to the therapeutic effects of deep brain stimulation

Deep brain stimulation (DBS) is a surgical procedure that entails the delivery of high-frequency electrical impulses to specific regions of the brain, via surgically implanted electrodes. While it requires an invasive surgical ...

Genetics

Common genetic causes across motor neuron diseases identified

Motor neuron diseases, such as amyotrophic lateral sclerosis (ALS) and hereditary spastic paraplegia (HSP), share physical similarities but have been largely viewed as genetically distinct. However, an analysis led by investigators ...

Parkinson's & Movement disorders

Advancement for people with Parkinson's in light therapy trial

Australian-founded medical technology company SYMBYX today announced compelling results from a 72-week randomized controlled trial (RCT) demonstrating improvements in a range of Parkinson's disease symptoms. These results, ...

Neuroscience

Burden of pain significantly higher in Parkinson's patients

A major QIMR Berghofer-led study has found that Australians living with Parkinson's disease are nearly three times more likely to suffer from chronic pain compared to the general community, with two-thirds of patients experiencing ...

Neuroscience

How fruit flies can help us understand diseases such as ALS

If we can understand exactly how neurodegenerative diseases such as ALS progress in fruit flies, we may also gain valuable insights into how these diseases develop in humans. Research by neurobiologist Marije Been of Radboud ...

Neuroscience

Restless leg syndrome's connection to Parkinson's disease

Three research hospitals in the Republic of Korea are reporting that restless leg syndrome was associated with an increased risk of Parkinson's disease, with 1.6% of patients with restless leg syndrome developing Parkinson's ...

Parkinson's & Movement disorders

New evidence suggests link between gut health and Parkinson's disease

While previous studies suggest Parkinson's disease begins in the gut and spreads to the brain, how the process occurs has been elusive. Now, a pre-clinical study led by Duke Health researchers provides new evidence that bolsters ...

Neuroscience

Unlocking the secrets of the brain's dopaminergic system

A new organoid model of the dopaminergic system sheds lights on its intricate functionality and potential implications for Parkinson's disease. The model, developed by the group of Jürgen Knoblich at the Institute of Molecular ...

Neuroscience

Brain stimulation decreases involuntary shaking, researcher finds

Neurosurgical treatment with deep brain stimulation in a relatively new target area has been shown to relieve involuntary tremors in Parkinson's disease and Essential Tremor for up to at least five and 10 years after treatment ...

Neuroscience

Neural circuit location of strong sense of discomfort found

Researchers have identified a new neural circuit in the brain which produces a strong sense of discomfort when activated. The discovery also allows them to show for the first time that the subthalamic nucleus, a structure ...

Parkinson's & Movement disorders

Parkinson's research: New hope when treatment options seem exhausted

As Parkinson's progresses, more invasive therapies are used, for example, those that require brain surgery. When these therapies no longer deliver the desired results, physicians often conclude that treatment options are ...

Parkinson's & Movement disorders

Parkinson's disease and normal aging

A new research perspective titled "Cholinergic centro-cingulate network in Parkinson disease and normal aging" has been published in Aging.