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Parkinson's & Movement disorders news
Parkinson's & Movement disorders
AI detects subtle movement changes in finger-tapping videos, revealing hidden Parkinson's signs
Early detection of even the slightest motor function changes can be critical to slowing the progression of Parkinson's disease. Yet these subtle signs often go unnoticed. Now, UF researcher Diego L. Guarín, Ph.D., is harnessing ...
Sep 10, 2025
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Neuroscience
Rethinking how our brains build the neural networks underlying motor memories
For every motor skill you've ever learned, whether it's walking or watchmaking, there is a small ensemble of neurons in your brain that makes that movement happen. Our brains trigger these ensembles—what we sometimes call ...
Sep 9, 2025
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Why a promising ALS drug failed—despite hitting its target
A new Emory University study, led by the Emory ALS Center and the Center for Neurodegenerative Disease at Emory's Goizueta Brain Health Institute, sheds light on why a once-promising experimental medication for amyotrophic ...
Sep 9, 2025
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How DNA damage can lead to motor neuron disease
Researchers at the University of Bath have discovered how DNA damage caused by a faulty DNA protection and repair system can lead to neurodegenerative disorders such as motor neuron disease (MND).
Sep 8, 2025
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Pain questionnaires adapted for young people with cerebral palsy
Researchers from the University of Adelaide have taken existing questionnaires used to measure chronic pain and made them accessible for children and young people with cerebral palsy.
Sep 8, 2025
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Single hair strand could provide biomarker for amyotrophic lateral sclerosis
Researchers at the Icahn School of Medicine at Mount Sinai have shown for the first time that a single strand of hair can reveal unique elemental patterns that distinguish people with amyotrophic lateral sclerosis (ALS) from ...
Sep 4, 2025
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Microscopic pores in brain cells may be key to understanding Parkinson's
A toxic protein forms dynamic pores in the membranes of brain cells—and that may be the key to understanding how Parkinson's disease develops. This is the conclusion of a new study from Aarhus University, where researchers ...
Sep 4, 2025
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Scientists reveal brain signaling that sets Parkinson's disease apart from essential tremor
Researchers have identified a neurochemical signature that sets Parkinson's disease apart from essential tremor—two of the most common movement disorders, but each linked to distinct changes in the brain.
Sep 2, 2025
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Parkinson's disease drug candidates induce unexpected damaging effects
Parkinson's disease is the second most common neurodegenerative disease, affecting over 10 million people worldwide. Some forms of Parkinson's disease are characterized by an inability of cells to clean up dysfunctional mitochondria, ...
Aug 27, 2025
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Overworked brain cells may burn out in Parkinson's disease
Certain brain cells are responsible for coordinating smooth, controlled movements of the body. But when those cells are constantly overactivated for weeks on end, they degenerate and ultimately die. This new observation made ...
Aug 27, 2025
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Novel backpack enhances stability for people with ataxia
A newly designed backpack, incorporating aerospace technology, shows promise as a balance aid for patients with the movement disorder ataxia. Research conducted by Radboud university medical center, in collaboration with ...
Aug 27, 2025
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Biodegradable self-healing hydrogel combined with acupuncture shows promise for Parkinson's disease
Researchers at National Taiwan University developed a biodegradable, electroconductive self-healing hydrogel combined with acupuncture that restores motor function and protects brain neurons in Parkinson's disease models.
Aug 26, 2025
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Open-label Phase II trial reports early motor milestones with risdiplam
From Johns Hopkins University School of Medicine, Charlotte J. Sumner, M.D., presents an editorial on a study by Richard S. Finkel and colleagues, who report an open-label, Phase II trial of the pre-messenger RNA splicing ...
Metabolic syndrome linked to increased risk for Parkinson's disease
Metabolic syndrome (MetS) is associated with an increased risk for Parkinson's disease (PD), according to a study published online Aug. 20 in Neurology.
Aug 21, 2025
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Wearable robot adapts to individual arm movement patterns for stroke and ALS patients
Having lived with an ALS diagnosis since 2018, Kate Nycz can tell you firsthand what it's like to slowly lose motor function for basic tasks. "My arm can get to maybe 90 degrees, but then it fatigues and falls," the 39-year-old ...
Aug 20, 2025
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Parkinson's disease risk increases with metabolic syndrome, study finds
Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of Parkinson's disease, according to a study published in Neurology. The study does ...
Aug 20, 2025
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Immune tolerance observed in iPS cell-derived neural transplants for Parkinson's disease
A research team involved in the recently published successful transplantation of allogeneic iPS cell-derived dopaminergic neural progenitors into patients with Parkinson's disease, led by former Junior Associate Professor ...
Aug 20, 2025
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Surprising gene activity shields certain nerve cells from ALS damage
By analyzing millions of messenger RNA molecules (mRNA) during the course of ALS, researchers at Stockholm University, in collaboration with scientists at the Paris Brain Institute and Örebro University, have identified ...
Aug 19, 2025
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Clinical trial shows newborns with spinal muscular atrophy can start treatment at birth
Spinal muscular atrophy (SMA) is a rare genetic condition that causes progressive muscle weakness, which, when untreated, prevents infants with the most severe form from gaining motor development—never gaining the ability ...
Aug 14, 2025
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Straightforward method can more accurately determine severity of movement disorder in children
Cerebral palsy affects around one in 345 children in the U.S., and more than half of them experience a problem called dystonia—involuntary and often painful muscle contractions, most commonly in the legs, that lead to abnormal ...
Aug 14, 2025
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Making neurons young again may stop ALS
In the beginning, not even Hynek Wichterle's postdoc thought his idea to slow the progression of amyotrophic lateral sclerosis (ALS) had a chance.
Aug 13, 2025
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Rodent study reveals different signaling codes for learned skills and clues about human movement disorders
Among the many wonders of the brain is its ability to master learned movements—a dance step, piano sonata, or tying our shoes—acquired through trial-and-error practice. For decades, neuroscientists have known that these ...
Aug 11, 2025
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Regular exercise linked to slower neurodegeneration in Parkinson's disease
For patients with early Parkinson's disease (PD), regular physical activity is associated with a slower rate of neurodegeneration, according to a study published online in Neurology.
Aug 7, 2025
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Low-oxygen air slows Parkinson's progression and restores movement in mice
Researchers from the Broad Institute and Mass General Brigham have shown that a low-oxygen environment—similar to the thin air found at Mount Everest base camp—can protect the brain and restore movement in mice with Parkinson's-like ...
Aug 6, 2025
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Stem cells created from ALS patients point to potential new target for treatment
Amyotrophic lateral sclerosis (ALS), known as Lou Gehrig's disease, is an incurable neurological disorder affecting motor neurons—nerve cells in the brain and spinal cord that control voluntary muscle movement and breathing.
Aug 5, 2025
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