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Parkinson's & Movement disorders news

Alzheimer's disease & dementia

Blood plasma reveals shared pathways in neurodegenerative diseases

Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...

Alzheimer's disease & dementia

A shared five biomarker profile across four major neurodegenerative diseases

The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts to identify patterns in neurodegenerative disease. Sifting through roughly 250 million plasma measurements, ...

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Neuroscience

How Parkinson's disease affects emotion recognition of voices

A new study in Neurodegenerative Diseases looks closely at how Parkinson's disease can affect something as everyday and essential as recognizing emotion in someone's voice. The research suggests that both the side of the ...

Parkinson's & Movement disorders

Mouth and gut bacteria linked to brain changes in Parkinson's disease

Scientists have discovered a link between bacteria in the mouth and gut and the progression of cognitive decline in Parkinson's disease. Specific changes in these bacteria, known as the microbiome, have been associated with ...

Medications

Asthma drug could help to treat a rare neurological disorder

The asthma medication theophylline is a suitable drug for treating the rare neurological disorder ADCY5-related dyskinesia, according to a new study by Martin Luther University Halle-Wittenberg (MLU), which was published ...

Parkinson's & Movement disorders

Exercise hormone halts Parkinson's disease symptoms in mouse study

Researchers from Johns Hopkins Medicine and the Dana Farber Cancer Institute in Boston have shown that a hormone secreted into the blood during endurance, or aerobic, exercise reduces levels of a protein linked to Parkinson's ...

Parkinson's & Movement disorders

Building momentum against Parkinson's

A team led by researchers at Brigham and Women's Hospital and Harvard Medical School has taken a step toward solving a central mystery of Parkinson's disease: What is the normal function of the protein whose misfolding causes ...

Neuroscience

Brain's support cells may hold key to new Huntington's treatments

Huntington's disease—a hereditary and fatal genetic disorder—has long been considered a neuronal disease due to the permanent loss of medium spiny motor neurons, the death of which over time is responsible for the clinical ...

Parkinson's & Movement disorders

Is it Parkinson's? These 10 signs could tell

Parkinson's disease can be hard for the average person to identify, but 10 warning signs may offer an early clue that you or a loved one may be developing the disease.

Parkinson's & Movement disorders

A new wearable system tracks Parkinson's disease symptoms remotely

Parkinson's disease affects 10 million people worldwide and its symptoms include tremors in the fingers and hands, small handwriting, loss of smell, walking difficulties, dizziness, and others. As these symptoms worsen over ...

Neuroscience

Scientists zero in on genetic causes of Parkinson's

Variants of at least 20 different genes have been closely linked to the development of Parkinson's disease, but scientists are still investigating how exactly they cause the severe and incurable motor disorder that afflicts ...

Parkinson's & Movement disorders

Spotting Parkinson's disease through AI

Tracking wearable sensors, filming the patients performing routine exercises, or examining their handwriting—which is better for Parkinson's detection? Researchers at Skoltech performed a comparative study of these three ...

Neuroscience

Copper leads to protein aggregation in Parkinson's disease

Copper exposure in the environment and the protein alpha-synuclein in the human brain could play an important role in the pathogenesis of Parkinson's disease. A team from Empa and the University of Limerick was able to show ...

Parkinson's & Movement disorders

A new cause of Parkinson's disease-related cell death

There is currently no cure for Parkinson's disease (PD), and one of the main difficulties for developing treatments is that we don't know exactly how or why the disease occurs. It's generally believed that a buildup of Lewy ...

Parkinson's & Movement disorders

Parkinson's disease: Bad dreams could be an early warning sign

Every night when we go to sleep, we spend a couple of hours in a virtual world created by our brains in which we are the main protagonist of an unfolding story we did not consciously create. In other words, we dream.

Parkinson's & Movement disorders

Prospect of blood test for Parkinson's disease

A research team at the Faculty of Medicine at Kiel University has developed a method that reliably detects protein changes in blood that are typical of Parkinson's disease.

Parkinson's & Movement disorders

Boxing may ease Parkinson's symptoms

Researchers are looking to the boxing ring for new options in the fight against Parkinson's disease symptoms.