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Parkinson's & Movement disorders news

Alzheimer's disease & dementia

A shared five biomarker profile across four major neurodegenerative diseases

The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts to identify patterns in neurodegenerative disease. Sifting through roughly 250 million plasma measurements, ...

Alzheimer's disease & dementia

Blood plasma reveals shared pathways in neurodegenerative diseases

Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Neuroscience

How Parkinson's disease affects emotion recognition of voices

A new study in Neurodegenerative Diseases looks closely at how Parkinson's disease can affect something as everyday and essential as recognizing emotion in someone's voice. The research suggests that both the side of the ...

Parkinson's & Movement disorders

Mouth and gut bacteria linked to brain changes in Parkinson's disease

Scientists have discovered a link between bacteria in the mouth and gut and the progression of cognitive decline in Parkinson's disease. Specific changes in these bacteria, known as the microbiome, have been associated with ...

Medications

Asthma drug could help to treat a rare neurological disorder

The asthma medication theophylline is a suitable drug for treating the rare neurological disorder ADCY5-related dyskinesia, according to a new study by Martin Luther University Halle-Wittenberg (MLU), which was published ...

Parkinson's & Movement disorders

Shining a light on protein aggregation in Parkinson's disease

A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9 in the open-access journal ...

Parkinson's & Movement disorders

Scientists uncover new targets for treating Parkinson's disease

Scientists at La Jolla Institute for Immunology (LJI) have found that people with Parkinson's disease have a clear "genetic signature" of the disease in their memory T cells. The scientists hope that targeting these genes ...

Parkinson's & Movement disorders

COVID-19 vaccines do not impact IVF success

(HealthDay)—Receipt of a COVID-19 mRNA vaccine does not affect the ovarian response or pregnancy rates in in vitro fertilization (IVF) treatment, according to a study published online Feb. 25 in Fertility and Sterility.

Parkinson's & Movement disorders

Skin biopsy can help identify patients with Parkinson's disease

The diagnosis of Parkinson's disease (PD) is currently based on consensus clinical criteria. A novel study reported in the Journal of Parkinson's Disease has found that the presence of neuronal deposits of the biomarker phosphorylated ...

Parkinson's & Movement disorders

The gut-brain axis in Parkinson's disease

Parkinson's disease (PD) is a progressive and complex disorder that affects multiple parts of the brain but also other organ systems. Symptoms start gradually, sometimes with a barely noticeable tremor in just one hand. Tremor ...

Neuroscience

Discovery points to possible driver of Parkinson's disease

Parkinson's disease may be driven in part by cell stress-related biochemical events that disrupt a key cellular cleanup system, leading to the spread of harmful protein aggregates in the brain, according to a new study from ...

Parkinson's & Movement disorders

'E-nose' could someday diagnose Parkinson's disease by 'smelling' skin

A couple of years ago, a woman named Joy Milne made headlines when scientists discovered that she could "smell" Parkinson's disease (PD) on people with the neurodegenerative disorder. Since then, researchers have been trying ...

Parkinson's & Movement disorders

Improving treatment for Parkinson's

Parkinson's is a neurodegenerative disease where dopaminergic neurons progressively die in the brainstem. Tremor and difficulties walking are recognizable movement symptoms for many people suffering from Parkinson's. Over ...