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Parkinson's & Movement disorders news
Neuroscience
Tailored deep brain stimulation improves walking in Parkinson's disease
For patients with Parkinson's disease, changes in their ability to walk can be dramatic. "Parkinson's gait," as it is often called, can include changes in step length and asymmetry between legs. This gait dysfunction reduces ...
15 hours ago
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Alzheimer's disease & dementia
A shared five biomarker profile across four major neurodegenerative diseases
The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts to identify patterns in neurodegenerative disease. Sifting through roughly 250 million plasma measurements, ...
Jul 21, 2025
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Blood plasma reveals shared pathways in neurodegenerative diseases
Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...
Jul 21, 2025
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Skin swabs could detect Parkinson's disease up to seven years before symptoms appear
A new study has revealed promising progress in developing a non-invasive sampling method to detect early signs of Parkinson's disease—up to seven years before motor symptoms appear—by analyzing the chemical makeup of ...
Jul 14, 2025
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Weekly injection offers steady Parkinson's medication, reducing need for daily pills
A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.
Jul 11, 2025
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'Harmless' virus might trigger Parkinson's disease, researchers say
A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...
Jul 9, 2025
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Parkinson's disease: How the affected side shapes the disease's course
Parkinson's disease affects approximately 10 million people worldwide. It typically begins asymmetrically, initially impacting only one side of the body. Although it first manifests through motor symptoms—such as tremors, ...
Jul 7, 2025
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Burden of tremor recognized for Parkinson's disease patients
Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...
Jul 2, 2025
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Q&A: Are mitochondria the key to a healthy brain?
Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...
Jul 2, 2025
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Theater can improves emotional symptoms of people with Parkinson's
A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...
Jul 2, 2025
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Inhibiting enzyme could halt cell death in Parkinson's disease, study finds
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.
Jul 1, 2025
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Cough medicine Ambroxal shows potential to slow Parkinson's-related dementia
Dementia poses a major health challenge with no safe, affordable treatments to slow its progression. Researchers at Lawson Research Institute (Lawson), the research arm of St. Joseph's Health Care London, are investigating ...
Jun 30, 2025
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Targeting newly-identified brain protein brings hope of new treatment for Parkinson's disease
Groundbreaking research by the University of Sydney has identified a new brain protein involved in the development of Parkinson's disease and a way to modify it, paving the way for future treatments for the disease.
Jun 26, 2025
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Blood test shows promise for early dementia with Lewy Bodies diagnosis
A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...
Jun 26, 2025
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Gene therapy may slow loss of motor function in ALS
Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.
Jun 25, 2025
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'ALS on a chip' model reveals altered motor neuron signaling
Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.
Jun 24, 2025
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Ear wax as a possible screening medium for Parkinson's disease
Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...
Jun 18, 2025
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T cells may allow for early detection of Parkinson's cases, years before motor symptoms develop
Your T cells work hard to fight disease. Unfortunately, "friendly fire" from T cells can sometimes harm the body's healthy tissues.
Jun 18, 2025
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Glial replacement therapy slows Huntington's disease in adult mice
Huntington's disease has long defied attempts to rescue suffering neurons. A new study in Cell Reports shows that transplanting healthy human glial progenitor cells into the brains of adult animal models of the disease not ...
Jun 16, 2025
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Gut microbiome study links Parkinson's disease to environmental chemicals
Parkinson's disease is a progressive and common neurodegenerative condition, typically characterized by involuntary shaking, stiffness, and slow movement. Beyond these motor symptoms, individuals often experience a range ...
Jun 12, 2025
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How Parkinson's disease affects emotion recognition of voices
A new study in Neurodegenerative Diseases looks closely at how Parkinson's disease can affect something as everyday and essential as recognizing emotion in someone's voice. The research suggests that both the side of the ...
Jun 10, 2025
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Mouth and gut bacteria linked to brain changes in Parkinson's disease
Scientists have discovered a link between bacteria in the mouth and gut and the progression of cognitive decline in Parkinson's disease. Specific changes in these bacteria, known as the microbiome, have been associated with ...
Jun 9, 2025
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Smartphone tests could accelerate drug development for Huntington's disease
A series of digital tests carried out via a smartphone app could enhance the detection of disease progression in Huntington's disease and improve the efficiency of clinical trials, finds research led by scientists at University ...
Jun 9, 2025
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Diagnostic pen converts handwriting into electrical signals to detect Parkinson's
A team at the University of California, Los Angeles has developed a low-cost diagnostic pen that converts handwriting into electrical signals for early detection of Parkinson's disease, achieving 96.22% accuracy in a pilot ...
Faulty RNA 'tails' may drive neuron failure in ALS, study suggests
UC Irvine researchers conducted a study to better understand the molecular basis of amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder in which patients lose the ability to move, becoming weak and wheelchair ...
Jun 4, 2025
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