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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

Newly discovered cellular trigger could lead to possible therapies for Parkinson's disease

Autophagy is essentially the "rubbish collection" of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists ...

Neuroscience

Exposure to the pesticide rotenone disrupts genes in Parkinson's-linked brain regions

Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new research reveals.

Parkinson's & Movement disorders

Can Amazon Alexa or Google Home help detect Parkinson's?

Computer scientists at the University of Rochester have developed an AI-powered, speech-based screening tool that can help people assess whether they are showing signs of Parkinson's disease, the fastest growing neurological ...

Alzheimer's disease & dementia

Blood plasma reveals shared pathways in neurodegenerative diseases

Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...

Diseases, Conditions, Syndromes

'Harmless' virus might trigger Parkinson's disease, researchers say

A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...

Neuroscience

Burden of tremor recognized for Parkinson's disease patients

Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...

Neuroscience

Q&A: Are mitochondria the key to a healthy brain?

Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...

Psychology & Psychiatry

Theater can improves emotional symptoms of people with Parkinson's

A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...

Alzheimer's disease & dementia

Blood test shows promise for early dementia with Lewy Bodies diagnosis

A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...

Genetics

Gene therapy may slow loss of motor function in ALS

Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.

Parkinson's & Movement disorders

'ALS on a chip' model reveals altered motor neuron signaling

Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.

Parkinson's & Movement disorders

Ear wax as a possible screening medium for Parkinson's disease

Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...

Parkinson's & Movement disorders

Gut bacteria could be responsible for side effect of Parkinson's drug

Bacteria in the small intestine can deaminate levodopa, the main drug that is used to treat Parkinson's disease. Bacterial processing of the unabsorbed fractions of the drug results in a metabolite that reduces gut motility. ...

Parkinson's & Movement disorders

Even in people with Parkinson's gene, coffee may be protective

Even for people with a gene mutation tied to Parkinson's disease, coffee consumption may be associated with a lower risk of actually developing the disease, according to a new study published in the September 30, 2020, online ...

Parkinson's & Movement disorders

Finding right drug balance for Parkinson's patients

Parkinson's disease is most commonly treated with levodopa, a drug which alleviates the slowing of bodily movements, called bradykinesia, found in Parkinson's disease patients.

Neuroscience

Stem cells can repair Parkinson's-damaged circuits in mouse brains

The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson's. Stem cells, which are endlessly adaptable, have offered the promise ...

Parkinson's & Movement disorders

Parkinson's disease can affect the eyes, and here's what we know so far

Parkinson's disease is the second most common neurodegenerative disease, affecting over 10 million people worldwide. It's characterized by changes in movement, including tremors, and slower and more rigid movements. But researchers ...

Parkinson's & Movement disorders

People with Parkinson's disease can have a brighter future

Well over six million people globally have been diagnosed with Parkinson's disease, which has an enormous impact on the lives of patients and their families and incurring mounting costs for society. In this special supplement ...

Parkinson's & Movement disorders

Parkinson's disease is not one, but two diseases

Although the name may suggest otherwise, Parkinson's disease is not one but two diseases, starting either in the brain or in the intestines. Which explains why patients with Parkinson's describe widely differing symptoms, ...

Neuroscience

Improving prediction of Parkinson's disease

Including genetic markers in addition to well known risk factors improves tests to predict Parkinson's disease, according to a study led by Queen Mary University of London.

Parkinson's & Movement disorders

Diagnosis of neurological diseases to benefit from AI

Cutting-edge artificial intelligence technology for diagnosing neurological disease such as Parkinson's and Alzheimer's from eye scans will be tested and scaled in the NHS.

Neuroscience

Brain astrocytes show metabolic alterations in Parkinson's disease

A new study using induced pluripotent stem cell (iPSC) technology links astrocyte dysfunction to Parkinson's disease (PD) pathology. The study carried out at the University of Eastern Finland and published in Scientific Reports ...