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Parkinson's & Movement disorders news
Genetics
Research confirms role of DJ-1 gene in Parkinson's disease
A mutant DJ-1 gene causes recessive Parkinson's disease, but the molecular mechanism of this process has not been well studied. To understand how DJ-1 hydrolyzes cyclic 3-phosphoglyceric anhydride—a highly reactive, toxic ...
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Parkinson's & Movement disorders
Unmet potential: How ALS patients and caregivers are missing out on accessibility features in everyday technology
A recent study has revealed a critical gap in the use of accessibility features among people living with Amyotrophic Lateral Sclerosis (ALS) and their caregivers. Though over 90% of ALS patients surveyed reported daily use ...
Jul 29, 2025
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Detecting a potential behavioral biomarker for Parkinson's disease in mice
Detecting early rising Parkinson's disease (PD) symptoms could improve treatment outcomes by enabling earlier treatment interventions. In a new eNeuro paper, Daniil Berezhnoi, from Georgetown University, and colleagues used ...
Jul 28, 2025
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Newly discovered cellular trigger could lead to possible therapies for Parkinson's disease
Autophagy is essentially the "rubbish collection" of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest study, leading cell biologists ...
Jul 25, 2025
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Exposure to the pesticide rotenone disrupts genes in Parkinson's-linked brain regions
Cells in key brain regions involved in Parkinson's retain a "memory" of pesticide exposure that disrupts gene expression, new research reveals.
Jul 24, 2025
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Can Amazon Alexa or Google Home help detect Parkinson's?
Computer scientists at the University of Rochester have developed an AI-powered, speech-based screening tool that can help people assess whether they are showing signs of Parkinson's disease, the fastest growing neurological ...
Jul 24, 2025
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The many faces of Parkinson's: Symptoms, treatment, and how to manage it
About 90,000 people are diagnosed with Parkinson's disease (PD) each year—one person every six minutes. While most people associate PD with tremors and stiffness, the condition is far more complex than these symptoms and ...
Jul 24, 2025
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What to know about Parkinson's disease after Ozzy Osbourne's death
Heavy metal rocker Ozzy Osbourne died this week at 76, just weeks after his farewell show and about five years after announcing he had Parkinson's disease.
Jul 23, 2025
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Tailored deep brain stimulation improves walking in Parkinson's disease
For patients with Parkinson's disease, changes in their ability to walk can be dramatic. "Parkinson's gait," as it is often called, can include changes in step length and asymmetry between legs. This gait dysfunction reduces ...
Jul 22, 2025
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A shared five biomarker profile across four major neurodegenerative diseases
The Global Neurodegeneration Proteomics Consortium (GNPC) has published a series of research papers detailing their efforts to identify patterns in neurodegenerative disease. Sifting through roughly 250 million plasma measurements, ...
Blood plasma reveals shared pathways in neurodegenerative diseases
Scientists know that many proteins and pathways are involved in the development and progression of neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease and frontotemporal dementia (FTD), and that ...
Jul 21, 2025
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Skin swabs could detect Parkinson's disease up to seven years before symptoms appear
A new study has revealed promising progress in developing a non-invasive sampling method to detect early signs of Parkinson's disease—up to seven years before motor symptoms appear—by analyzing the chemical makeup of ...
Jul 14, 2025
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Weekly injection offers steady Parkinson's medication, reducing need for daily pills
A new weekly injectable drug could transform the lives of more than eight million people living with Parkinson's disease, potentially replacing the need for multiple daily tablets.
Jul 11, 2025
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'Harmless' virus might trigger Parkinson's disease, researchers say
A common virus once thought harmless to humans might be linked to Parkinson's disease, a new study says. The germ, Human Pegivirus (HPgV), was found in half the autopsied brains of patients with Parkinson's, but not in any ...
Jul 9, 2025
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Parkinson's disease: How the affected side shapes the disease's course
Parkinson's disease affects approximately 10 million people worldwide. It typically begins asymmetrically, initially impacting only one side of the body. Although it first manifests through motor symptoms—such as tremors, ...
Jul 7, 2025
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Burden of tremor recognized for Parkinson's disease patients
Some 25 years ago, a young Parkinson's disease investigator, Robert Hauser, MD, stepped to the podium at an American Academy of Neurology Conference to present findings from his patient survey that didn't quite jibe with ...
Jul 2, 2025
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Q&A: Are mitochondria the key to a healthy brain?
Elizabeth Jonas first got interested in mitochondria by chance. In 1995, she was a postdoctoral researcher at Yale, working at the Marine Biological Lab in Woods Hole, Massachusetts, where she was trying to record electrical ...
Jul 2, 2025
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Theater can improves emotional symptoms of people with Parkinson's
A research team at the Universitat Oberta de Catalunya, working with the Hospital Sant Pau in Barcelona, has shown that theater can improve the emotional well‐being of people with Parkinson's disease. The study, "Efficacy ...
Jul 2, 2025
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Inhibiting enzyme could halt cell death in Parkinson's disease, study finds
Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson's disease that's caused by a single genetic mutation, according to a new Stanford Medicine-led study conducted in mice.
Jul 1, 2025
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Cough medicine Ambroxal shows potential to slow Parkinson's-related dementia
Dementia poses a major health challenge with no safe, affordable treatments to slow its progression. Researchers at Lawson Research Institute (Lawson), the research arm of St. Joseph's Health Care London, are investigating ...
Jun 30, 2025
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Targeting newly-identified brain protein brings hope of new treatment for Parkinson's disease
Groundbreaking research by the University of Sydney has identified a new brain protein involved in the development of Parkinson's disease and a way to modify it, paving the way for future treatments for the disease.
Jun 26, 2025
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Blood test shows promise for early dementia with Lewy Bodies diagnosis
A research team has made a significant finding that sheds new light on dementia with Lewy Bodies (DLB). The team was led by Associate Professor Ayako Okado-Matsumoto from the Department of Biology at Toho University in collaboration ...
Jun 26, 2025
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Gene therapy may slow loss of motor function in ALS
Researchers have developed a gene therapy that significantly slowed motor function loss in preclinical models of amyotrophic lateral sclerosis (ALS), offering new hope for treating the devastating neurodegenerative disease.
Jun 25, 2025
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'ALS on a chip' model reveals altered motor neuron signaling
Using stem cells from patients with ALS (amyotrophic lateral sclerosis), Cedars-Sinai has created a lifelike model of the mysterious and fatal disease that could help identify a cause of the illness as well as effective treatments.
Jun 24, 2025
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Ear wax as a possible screening medium for Parkinson's disease
Most treatments for Parkinson's disease (PD) only slow disease progression. Early intervention for the neurological disease that worsens over time is therefore critical to optimize care, but that requires early diagnosis. ...
Jun 18, 2025
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