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Parkinson's & Movement disorders news

Parkinson's & Movement disorders

Advancement for people with Parkinson's in light therapy trial

Australian-founded medical technology company SYMBYX today announced compelling results from a 72-week randomized controlled trial (RCT) demonstrating improvements in a range of Parkinson's disease symptoms. These results, ...

Neuroscience

Study unveils mechanisms driving axonal accumulation of TDP-43 and associated nerve damage in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive muscle wasting and limb paralysis. This neurodegenerative condition results from the gradual destruction of motor neurons, the ...

Neuroscience

Burden of pain significantly higher in Parkinson's patients

A major QIMR Berghofer-led study has found that Australians living with Parkinson's disease are nearly three times more likely to suffer from chronic pain compared to the general community, with two-thirds of patients experiencing ...

Neuroscience

How fruit flies can help us understand diseases such as ALS

If we can understand exactly how neurodegenerative diseases such as ALS progress in fruit flies, we may also gain valuable insights into how these diseases develop in humans. Research by neurobiologist Marije Been of Radboud ...

Neuroscience

Restless leg syndrome's connection to Parkinson's disease

Three research hospitals in the Republic of Korea are reporting that restless leg syndrome was associated with an increased risk of Parkinson's disease, with 1.6% of patients with restless leg syndrome developing Parkinson's ...

Genetics

How gene mutations drive dementia in Parkinson's disease

Parkinson's disease causes both movement and cognitive deficits, and for a long time both were thought to be caused by the accumulation of a protein called alpha-synuclein in the brain. But a new Nature Communications study ...

Parkinson's & Movement disorders

Oral bacteria linked to Parkinson's via the gut-brain axis

Korean researchers have uncovered compelling evidence that oral bacteria, once colonized in the gut, can affect neurons in the brain and potentially trigger Parkinson's disease.

Neuroscience

Blood test could lead to better diagnosis and management of ALS

ALS, or amyotrophic lateral sclerosis, can sometimes be difficult to diagnose or to predict how quickly the disease is likely to progress. A new study helps determine which blood tests are best at identifying and monitoring ...

Parkinson's & Movement disorders

Cholesterol metabolism byproduct linked to Parkinson's disease

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the journal PLOS Biology, the ...

Parkinson's & Movement disorders

FDA approves wearable infusion device for advanced Parkinson disease

The U.S. Food and Drug Administration has approved Onapgo (apomorphine hydrochloride) injection as the first and only subcutaneous apomorphine infusion device for the treatment of motor fluctuations in patients with advanced ...

Genetics

AI model identifies potential risk genes for Parkinson's disease

Researchers from the Cleveland Clinic Genome Center have successfully applied advanced artificial intelligence (AI) genetics models to Parkinson's disease. Researchers identified genetic factors in progression and FDA-approved ...

Neuroscience

Biotin may shield brain from manganese-induced damage, study finds

While manganese is an essential mineral involved in many bodily functions, both deficiency and excessive exposure can cause health issues. Maintaining a balanced diet typically provides sufficient manganese for most individuals; ...