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Medical research

Researchers identify 166 human pluripotent stem cell lines available for use in clinical applications

To date, more than 100 clinical trials with human pluripotent stem cell (hPSC)-derived products have been initiated worldwide and an increasing number of potential hPSC-derived clinical products have entered early developmental ...

Medical research

Finances leading factor for some cancer patients not enrolling in potentially life-saving clinical trials, study shows

A study by Case Western Reserve University and University Hospitals researchers has overturned long-held assumptions about why more cancer patients don't enroll in clinical trials that could potentially save their lives.

Medical research

Some ventilator settings can double airway stress

Mechanical ventilation saves lives, but the airflow it produces inside an intubated airway can also shape conditions linked to complications during long-term support. In a recent study, SUNY Polytechnic Institute faculty ...

Medical research

How embryos and the uterus 'talk' during implantation

A new study shows that the embryo and the uterine lining conduct an active "conversation" from the very earliest stages of implantation. They engage in a back and forth of tiny packages called extracellular vesicles and lipid ...

Medical research

Accelerating drug combination discovery with machine learning

Discovering effective drug combinations may now be easier thanks to a screening platform made public today by St. Jude Children's Research Hospital scientists. Many diseases, including cancers, require combinations of drugs ...

Medical research

Rats may seek cannabis to cope with stress

It isn't just people—when given the chance, rats may also use cannabis to cope with stress, according to a study by researchers at Washington State University.

Medical research

Mini brains, big questions: Science is racing ahead of ethics

In a little over ten years, organoid models—miniature, lab-grown clusters of cells that imitate real organs—have transformed how we study human development and disease while accelerating drug discovery. As a bonus, they've ...

Medical research

Key kidney sensor that helps control fluid balance identified

A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...