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T-bet protein found essential for maintaining flu-fighting memory B cells

At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the immune system, and immune cells produce a potentially lifesaving antibody against the virus. Antigen ...

Medical research

Olorofim Phase IIb trial shows efficacy in invasive fungal disease for patients with limited treatment options

Researchers from KU Leuven, the University of California Davis Medical Center, the University of Cologne, and over 20 collaborating institutions report that the antifungal olorofim demonstrated efficacy and tolerability in ...

Medical research

New AI model could help scientists pinpoint signs of cancer cells

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, ...

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A new drug could soon help treat cancer and viral infections

An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where ...

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When stem cells feel the squeeze, they start building bone

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

Medical research

Scientists create biological 'artificial intelligence' system

Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said ...

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Preclinical study unlocks a mystery of rapid mouth healing

Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered ...

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Prion protein may play key role in progression of glioblastoma

Glioblastoma (GBM), one of the most aggressive types of brain cancer, is one of the greatest challenges for medicine, both because it is difficult to treat and because of its high mortality rate. In Brazil, although no exact ...

Medical research

Scientists solve decades-long Parkinson's mystery

WEHI researchers have made a huge leap forward in the fight against Parkinson's disease, solving a decades-long mystery that paves the way for the development of new drugs to treat the condition.

Medical research

Transforming thymic carcinoma treatment with a dual approach

Thymic epithelial tumors are a rare group of malignancies originating in the thymus gland, that includes thymoma and thymic carcinoma. Among these, thymic carcinoma is the more aggressive subtype, characterized by high invasiveness, ...

Medical research

Medical infusion bags can release microplastics, study shows

Microplastics have been found almost everywhere that scientists have looked for them. Now, according to research published in Environment & Health, these bits of plastic—from 1 to 62 micrometers long—are present in the ...