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From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...

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Poor kidney health linked to higher levels of Alzheimer's biomarkers in blood

People with impaired kidney function have higher levels of Alzheimer's biomarkers in their blood, but not an increased risk of dementia, according to a study published in Neurology.

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Why stress can make your hair fall out: A two-part reaction

It's well known that stress can trigger hair loss. A new paper explores how this happens and how our response to stress can have long-term consequences for our scalps, research that may eventually yield insights into autoimmune ...

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Internet and lack of trust threatens patient–doctor bond

Physicians have worked to earn the trust of their patients for nearly 2,400 years, dating back to the days of Hippocrates, the father of Western medicine. Lucky for Hippocrates that his patients didn't have internet access.

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Stem cell organoids mimic aspects of early limb development

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.

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The 'Miracle Mineral Solution'—amazing cure or toxic illusion?

Miracle Mineral Solution, also known as MMS, has been marketed for years as a purported miracle cure for various conditions, including cancer, autism, and COVID-19. MMS is the marketing name for sodium chlorite (NaClO₂), ...

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When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

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How statins harm muscles—and how to stop it

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness ...

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Advancing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...

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Microprotein adipogenin found to regulate fat storage in cells

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows. ...

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French scientists probe mRNA's potential to fight cancer

Inside a lab in the French city of Orleans, scientists are testing out the limits of molecules in our body called messenger RNA—best known for being used in COVID-19 vaccines—in the hopes of finding a breakthrough treatment ...

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Researchers find serious flaws in trials with adult ADHD patients

Millions of adults around the world are diagnosed with ADHD every year, and there is a great need for research in the field. However, much clinical research on adult ADHD suffers from serious methodological shortcomings that ...

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People with severe diabetes cured in small stem cell trial

The cure for diabetes is a life free from daily insulin injections. Based on that criterion, ten out of 12 people (83%) in a new clinical trial were cured of their diabetes one year after receiving an advanced stem cell therapy.

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How dysfunction of a cellular calcium channel affects hearing

Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such as a whisper, are perceived ...

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Blood test might predict MS relapse

A blood test might predict when multiple sclerosis patients are about to suffer a relapse in their symptoms, a new study says.

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Scientists find new blood type in Guadeloupe woman

A French woman from the Caribbean island of Guadeloupe has been identified as the only known carrier of a new blood type, dubbed "Gwada negative," France's blood supply agency has announced.