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Key kidney sensor that helps control fluid balance identified

A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...

Medical research

From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...

Medical research

Why stress can make your hair fall out: A two-part reaction

It's well known that stress can trigger hair loss. A new paper explores how this happens and how our response to stress can have long-term consequences for our scalps, research that may eventually yield insights into autoimmune ...

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Internet and lack of trust threatens patient–doctor bond

Physicians have worked to earn the trust of their patients for nearly 2,400 years, dating back to the days of Hippocrates, the father of Western medicine. Lucky for Hippocrates that his patients didn't have internet access.

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Stem cell organoids mimic aspects of early limb development

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.

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The 'Miracle Mineral Solution'—amazing cure or toxic illusion?

Miracle Mineral Solution, also known as MMS, has been marketed for years as a purported miracle cure for various conditions, including cancer, autism, and COVID-19. MMS is the marketing name for sodium chlorite (NaClO₂), ...

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When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

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How statins harm muscles—and how to stop it

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness ...

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Advancing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...

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Microprotein adipogenin found to regulate fat storage in cells

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows. ...

Medical research

Global review identifies best treatments for neuropathic pain

A major international study has provided the most comprehensive evidence to date on treatments for neuropathic pain—defined as pain caused by disease of the nervous system, affecting up to 10% of the population worldwide.

Medical research

Blocking APOC1 protein can slow lymphoma cell growth

Diffuse large B-cell lymphoma (DLBCL) is the most common and fast-growing type of non-Hodgkin lymphoma, a cancer that affects the lymphatic system. It makes up around 30–40% of adult non-Hodgkin lymphoma cases worldwide. ...

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For advances in treating ACL injuries, look to dogs

Even after surgery, injuries to the anterior cruciate ligament (ACL) often lead to chronic pain and reduced mobility, with limited options for treatment. New research suggests that advances in knowledge and therapeutics may ...

Medical research

Exploring the effect of oxidizing compounds on melanoma cells

Melanoma is the most aggressive form of skin cancer. Although less common, it is the most serious due to its high potential for metastasis. Despite the health benefits of sunlight, prolonged exposure to ultraviolet rays is ...

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Crafting artificial skin from fish-based hydrogels

The skin is the largest organ in the human body. It makes up about 15% of our body weight and protects us from pathogens, dehydration and temperature extremes. Skin diseases are therefore more than just unpleasant—they ...