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Brain biomarkers of Alzheimer's disease can be detected as early as middle age

A Finnish population study shows that signs related to Alzheimer's disease may already be found in the brain in middle age. In the future, blood-based biomarkers associated with Alzheimer's disease could allow earlier detection ...

Medical research

Revealing how senescent cells shape aging at the single-cell level

A research team led by Professor Takuya Yamamoto (Department of Life Science Frontiers) and Professor Yasuhiro Yamada at the University of Tokyo has developed a novel in vivo system that reveals how senescent cells behave ...

Medical research

Researchers link CAR-T cell aging to cancer relapse

Mayo Clinic researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR-T cell therapy. Over time, the engineered immune cells age and lose their ...

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New AI model could help scientists pinpoint signs of cancer cells

The Chan Zuckerberg Initiative (CZI) reports its latest AI model aimed at helping researchers better understand how cells behave by focusing on the key networks that control cell behavior, making complex biological problems, ...

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A new drug could soon help treat cancer and viral infections

An international team of researchers led by Konstanz biologists has identified a molecular mechanism that regulates the activity of N-myristoyltransferases. This enzyme plays a role in biological signaling pathways, where ...

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When stem cells feel the squeeze, they start building bone

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.

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Scientists create biological 'artificial intelligence' system

Australian scientists have successfully developed a research system that uses 'biological artificial intelligence' to design and evolve molecules with new or improved functions directly in mammal cells. The researchers said ...

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Lyme borreliosis: New approach for developing targeted therapy

Lyme borreliosis is the most common tick-borne infectious disease in Europe. Up to 70,000 new cases are estimated each year in Austria alone. The bacterial infection can cause lasting health problems for patients.

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Snake research reveals insights into human intestinal regeneration

All animals possess some capacity for repairing and replacing the lining of their intestines, a process called intestinal regeneration. In mammals, including humans, this constant but relatively minor turnover of cells helps ...

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Six proteins may hold key to diagnosing early-onset preeclampsia

Preeclampsia is a life-threatening pregnancy complication marked by persistent high blood pressure that is even more serious when it occurs early in the first trimester. The exact cause of early-onset preeclampsia is unknown, ...