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Key kidney sensor that helps control fluid balance identified

A new study has identified a critical "pressure sensor" inside the kidney that helps the body control blood pressure and fluid levels. The finding helps explain how the kidneys sense changes in blood volume—something scientists ...

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From lab to clinic: Phase I trial of promising combination therapy for resistant ovarian cancer

Researchers at the University of Colorado Cancer Center have discovered a novel therapy combination that could offer new hope to ovarian cancer patients who do not respond to existing treatments. Conducted entirely at the ...

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Why stress can make your hair fall out: A two-part reaction

It's well known that stress can trigger hair loss. A new paper explores how this happens and how our response to stress can have long-term consequences for our scalps, research that may eventually yield insights into autoimmune ...

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Internet and lack of trust threatens patient–doctor bond

Physicians have worked to earn the trust of their patients for nearly 2,400 years, dating back to the days of Hippocrates, the father of Western medicine. Lucky for Hippocrates that his patients didn't have internet access.

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Stem cell organoids mimic aspects of early limb development

Scientists at EPFL have created a scalable 3D organoid model that captures key features of early limb development, revealing how a specialized signaling center shapes both cell identity and tissue organization.

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The 'Miracle Mineral Solution'—amazing cure or toxic illusion?

Miracle Mineral Solution, also known as MMS, has been marketed for years as a purported miracle cure for various conditions, including cancer, autism, and COVID-19. MMS is the marketing name for sodium chlorite (NaClO₂), ...

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When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

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How statins harm muscles—and how to stop it

Statins have transformed heart health, saving millions of lives by lowering cholesterol and reducing the risk of heart attacks and strokes. But for many patients, these drugs come with a troubling downside: muscle pain, weakness ...

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Advancing patient-reported outcomes in cancer clinical trials

The SISAQOL-IMI consortium, co-led by the European Organization for Research and Treatment of Cancer (EORTC) and Boehringer Ingelheim (BI), has published a paper in The Lancet Oncology outlining how its recommendations for ...

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Microprotein adipogenin found to regulate fat storage in cells

A microprotein called adipogenin appears to play a key role in helping fat cells store lipid droplets—a phenomenon that's pivotal for metabolic health, a study co-led by UT Southwestern Medical Center researchers shows. ...

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Brain signals linked to sweet taste preference discovered

Researchers at Stony Brook University used genetic manipulation in a laboratory brain model to demonstrate that neurosteroids, signals involved in mood regulation and stress, can reduce the sensitivity and preference for ...

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Nasal COVID-19 vaccine to enter US clinical trials

A nasal vaccine for COVID-19—based on technology developed at Washington University in St. Louis—is poised to enter a phase 1 clinical trial in the U.S. after an investigational new drug application from Ocugen, Inc. ...

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Protein structure at the heart of heart disease discovered

Low-density lipoproteins (LDL)—commonly known as bad cholesterol—have long been on scientists' radar as a major contributor to heart disease. But these microscopic troublemakers have hidden their inner workings behind ...

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Key takeaways from the latest research into gut bacteria

Weighing in at nearly 2 kilos, our gut bacteria seem to play an even bigger role than was previously thought. These bacteria can influence our mood and act as a communication center. Gut microbiota researchers Åsa Håkansson ...

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β-glucans show promise as adjuvants for allergy treatment

A recent study carried out by a research team from the Paul-Ehrlich-Institut investigated the immunomodulating properties of β-glucans. These are natural sugar compounds found in bacteria, fungi and grains. The results indicate ...

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Cannabinoids offer new hope for safe and effective pain relief

Chronic pain is a global health challenge, with current treatment options often limited by side effects, addiction risk, and diminished effectiveness over time. In a new study, Yale researchers identify alternative compounds ...