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Medical research news
Medical research
Budget cuts threaten the future of biomedical research—and the young scientists behind it
Over the last several months, a deep sense of unease has settled over laboratories across the United States. Researchers at every stage—from graduate students to senior faculty members—have been forced to shelve experiments, ...
3 hours ago
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Researchers reveal key differences in STING inhibition between humans and mice
Researchers have long focused on the STING (Stimulator of Interferon Genes) pathway as a way to harness the immune system's natural defenses against cancer. This pathway, which plays a key role in helping the body defend ...
Jul 3, 2025
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Change trackers: New consortium to catalog DNA mutations across human lifetime
From the time we are conceived and through old age, genetic mutations accumulate in all our tissues, eluding the body's typically efficient DNA repair machinery and potentially affecting our health and well-being.
Jul 3, 2025
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Preclinical study unlocks a mystery of rapid mouth healing
Bite the inside of your cheek, and the wound may vanish without a trace in a couple of days. A preclinical study co-led by Cedars-Sinai, Stanford Medicine and the University of California, San Francisco (UCSF), has discovered ...
Jul 2, 2025
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New cell signaling pathway found to shield blood vessels from hypertension damage
By creating artificial aging in mice, researchers at Lund University in Sweden have been able to track the formation of aneurysms in the walls of blood vessels.
Jul 2, 2025
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Rare lung cells trigger rapid repair after smoke or virus exposure in mice—a similar pathway may exist in humans
A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like those in wildfire smoke or respiratory viruses, Stanford Medicine researchers and their colleagues have ...
Jul 2, 2025
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A new identification method unlocks fast, targeted treatment for trauma injuries
A study by researchers at Rutgers Health has uncovered a way to precisely identify and target trauma sites in the body within minutes of injury. The findings, published in the journal Med, could revolutionize emergency care ...
Jul 2, 2025
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Benzaldehyde blocks pancreatic cancer spread by disrupting key protein interactions
Cancer cells have the capacity to multiply rapidly. The aggressive cancer cells undergo conversion from their tightly connected epithelial state into a mesenchymal state, which lacks contact restrictions and spreads easily ...
Jul 2, 2025
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Study finds overtraining syndrome tied to increased PARP1 protein in muscles
Excessive physical exercise, especially without adequate rest, can damage the human body in various ways. In severe cases, it can progress to overtraining syndrome, which is characterized by decreased performance and appetite, ...
Jul 2, 2025
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Using viral load tests to help predict mpox severity when skin lesions first appear
In August 2024, the World Health Organization declared a second "Public Health Emergency of International Concern" for mpox. The current outbreak in Africa is driven mainly by the clade I variant, with multiple countries ...
Jul 2, 2025
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Antifungal discovery offers hope against deadly drug-resistant infections
Candida auris is a dangerous fungal pathogen that has become a global health concern. It spreads easily in health care settings and can cause life-threatening infections, especially in patients with weakened immune systems. ...
Jul 2, 2025
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Study highlights major hurdles for multinational clinical trials in Europe
A new study by investigators from Europe, including the Netherlands and the United Kingdom (UK), has shed light on significant ethical, administrative, regulatory, and logistical (EARL) hurdles in delivering multinational ...
Jul 2, 2025
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Click chemistry PET imaging tracks antisense drug distribution in the brain
Assessing the distribution of a medication in the brain is critical for the treatment of a vast range of neurological disorders, especially conditions such as Parkinson's and Alzheimer's diseases. To that end, scientists ...
How modified RNA tricks the innate immune system
The innate immune system is the body's first line of defense against pathogens and foreign substances. An essential component of this system are pattern recognition receptors, which recognize non-self RNA—such as that from ...
Jul 1, 2025
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Unleashing potassium for better mitochondrial health and platelet biogenesis
A research team led by Professor Koji Eto revealed that disruptions of the KCNN4 potassium channel impair mitochondrial function and cytoskeletal organization in megakaryocytes, leading to reduced platelet production, thus ...
Jul 1, 2025
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Senescence uncovered: Scientists find worms can mimic mammalian cell aging process
Senescent cells, which are damaged and inflammatory, contribute significantly to aging. Researchers at the Max Planck Institute for Biology of Aging have found that worms can enter a senescent-like state, similar to that ...
Jun 30, 2025
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Researchers find serious flaws in trials with adult ADHD patients
Millions of adults around the world are diagnosed with ADHD every year, and there is a great need for research in the field. However, much clinical research on adult ADHD suffers from serious methodological shortcomings that ...
Jun 30, 2025
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Researchers explore the connection between programmed cell death and tissue regeneration
The delicate balance between cell death and regeneration is crucial for human health and longevity. Most mechanisms involved in programmed cell death (PCD) play a key role in normal tissue renewal and repair after injury. ...
Jun 30, 2025
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People with severe diabetes cured in small stem cell trial
The cure for diabetes is a life free from daily insulin injections. Based on that criterion, ten out of 12 people (83%) in a new clinical trial were cured of their diabetes one year after receiving an advanced stem cell therapy.
Jun 28, 2025
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How dysfunction of a cellular calcium channel affects hearing
Researchers at the University Medical Center Göttingen (UMG) have shown how a minimal change in a single ion channel increases the sensitivity of sensory cells in the inner ear. Even soft sounds, such as a whisper, are perceived ...
Jun 27, 2025
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New credit card-sized TB test could close the diagnostic gap in HIV hotspots
Current tuberculosis infection tests struggle to detect the disease in those with HIV. A common co-infection, HIV can hide TB from traditional tests by eliminating the immune cells relied upon to sound the alarm.
Jun 27, 2025
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How early 20th century closures of US medical schools resulted in drops in mortality
Efforts in the early 20th century to improve the quality of medical education in the United States led to a steep decline in the number of medical schools and medical school graduates. In a new study, researchers examined ...
Jun 27, 2025
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Liver organoid generates organ-specific blood vessels for the first time
Scientists from Cincinnati Children's and colleagues based in Japan report achieving a major step forward in organoid technology: producing liver tissue that grows its own internal blood vessels.
Jun 25, 2025
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Molecular-level discovery points to heart protein AIMP3 as potential target for new cardiac treatments
New findings by a team of molecular biologists at Brown University on the critical role of a protein called AIMP3 in heart function could inform new treatments for heart disease.
Jun 25, 2025
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