Archive: 25/08/2016

Targeting low-oxygen patches inside lung cancer tumors could help prevent drug resistance

With the right treatment schedule, medications known as hypoxia-activated prodrugs (HAPs) could help prevent drug resistance in a subtype of lung cancer, according to a study published in PLOS Computational Biology.

Aug 25, 2016

Broadly neutralizing HIV antibodies engineered to be better vaccine leads

One approach to HIV vaccine development relies on broadly neutralizing antibodies (bnAbs) that protect against different circulating HIV strains. bnAbs have been isolated from HIV-infected individuals, but they are highly ...

Aug 25, 2016

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Fighting penicilliosis—identification of fungal protein Mp1p as virulence factor

Penicilliosis, caused by the fungus Talaromyces marneffei, is a major opportunistic infection in Southeast Asia. A study published in PLOS Neglected Tropical Diseases reports that the fungal protein Mp1p is responsible for ...

Aug 25, 2016

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Face shape is in the genes

Many of the characteristics that make up a person's face, such as nose size and face width, stem from specific genetic variations, reports John Shaffer of the University of Pittsburgh in Pennsylvania, and colleagues, in a ...

Aug 25, 2016

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Trans-obturator tape cost-effective for urinary incontinence

(HealthDay)—For women with stress urinary incontinence, use of trans-obturator tape (TOT) is cost-effective compared with tension-free vaginal tape (TVT), according to a study published online Aug. 10 in BJOG: An International ...

Aug 25, 2016

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Decision support tools cut CT use in pediatric appendicitis workup

(HealthDay)—For pediatric patients, passive and active decision support tools can reduce unnecessary computed tomography (CT) imaging among pediatric patients undergoing workup for appendicitis, according to a study published ...

Aug 25, 2016

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Posttraumatic growth for parents post-NICU 'under-evaluated'

(HealthDay)—For parents of infants previously hospitalized in the neonatal intensive care unit (NICU), posttraumatic growth (PTG) is related to factors such as posttraumatic stress symptoms, positive reinterpretation and ...

Aug 25, 2016

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Fracking chemicals exposure may harm fertility in female mice

Prenatal exposure to chemicals used in hydraulic fracturing, or fracking, may threaten fertility in female mice, according to a new study published in the Endocrine Society's journal Endocrinology.

Aug 25, 2016