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Arthritis & Rheumatism news

Diseases, Conditions, Syndromes

Fine particles in pollution are associated with early signs of autoimmune disease

A new study has linked air pollution exposure and immune-system changes that often precede the onset of autoimmune diseases.

Arthritis & Rheumatism

Study uncovers beneficial relationship between gardening and osteoarthritis

Gardening/yardwork is one of the few forms of leisure physical activity that people tend to do more as they age. Osteoarthritis is the most common form of arthritis and a major cause of disability that also tends to occur ...

Arthritis & Rheumatism

New clinical guidelines address gap in Adult-onset Still's disease

Adult-onset Still's disease (AOSD) is a rare inflammatory disorder. Thanks to a new initiative, AOSD is now considered to be the adult counterpart of systemic juvenile idiopathic arthritis, but in both cases the cause is ...

Arthritis & Rheumatism

Why certain arthritis drugs don't work in rheumatoid arthritis

Cedars-Sinai investigators may have figured out why certain immunosuppressive treatments don't work well in rheumatoid arthritis. In a study published in Science Immunology, scientists trace the problem to specific changes ...

Arthritis & Rheumatism

Enzyme provides promising path to degenerative joint diseases cure

Degenerative joint diseases like osteoarthritis and intervertebral disk degeneration are conditions that affect millions of people worldwide, leading to pain and reduced mobility. These diseases remain incurable because current ...

Arthritis & Rheumatism

New points to consider in treatment-resistant psoriatic arthritis

Some people with psoriatic arthritis (PsA) may have a disease that is difficult to manage (D2M) or does not respond to treatment. EULAR—The European Alliance of Associations for Rheumatology—has released new evidence-based ...

Arthritis & Rheumatism

Why so many pro soccer players develop osteoarthritis

A new paper finds that retired UK male professional soccer players who reported foot or ankle injuries during their careers were more likely to develop osteoarthritis in retirement. Retired players treated routinely with ...

Arthritis & Rheumatism

SGLT-2 diabetes drugs linked to lower risk of autoimmune diseases

Sodium-glucose cotransporter-2 (SGLT-2) inhibitors used to treat type 2 diabetes are associated with an 11% lower risk of autoimmune rheumatic diseases, such as rheumatoid arthritis and lupus, compared with another group ...

Arthritis & Rheumatism

Arthritis pain rising: How state policies matter

New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.

Genetics

Gene linked to rheumatic disease controls cell movement

A team of researchers at Karolinska Institutet, together with colleagues from Linköping University, has uncovered the function of a gene called DIORA1 (FAM167A), previously linked to autoimmune rheumatic diseases such as ...

Arthritis & Rheumatism

App aids self-monitoring of some rheumatoid arthritis patients

Patient-initiated care supported with smartphone self-monitoring is noninferior to usual care for rheumatoid arthritis (RA) in patients with stable low disease activity, according to a study published online July 11 in Arthritis ...

Genetics

Gene variant links trigger finger and carpal tunnel syndrome

A new NDORMS study, published in The Lancet Rheumatology, has found a genetic variant that increases the risk of both carpal tunnel syndrome and trigger finger, and opens the door for new therapies that involve blocking the ...

Neuroscience

New study focuses on improving cognitive symptoms of lupus

A National Jewish Health led study recently published in Lupus finds that technology using video game-based cognitive therapy improves attention and executive functioning in patients with systemic lupus erythematosus (SLE).

Arthritis & Rheumatism

How mitochondrial damage ignites the 'auto-inflammatory fire'

Mitochondria are self-contained organelles (they possess their own mini-chromosome and DNA) residing within cells and are charged with the job of generating the chemical energy needed to fuel functions essential to life and ...

Arthritis & Rheumatism

Patients with lupus benefit from COVID-19 vaccine booster

People with systemic lupus erythematosus (SLE) who received a "booster" dose of SARS-CoV-2 vaccine after full vaccination are roughly half as likely to have a subsequent "breakthrough" COVID-19 infection, a new study shows.

Arthritis & Rheumatism

Discovery of molecular pathway through which stress affects lupus

Systemic lupus erythematosus (SLE) is an autoimmune disease that affects all the organ systems of the body. This chronic disease includes periods of illness, called flare ups, and periods of remission, when symptoms are few. ...

Arthritis & Rheumatism

Should clinicians reconsider standard therapy for gout?

Gout occurs when urate crystals accumulate in the joints, and xanthine oxidase inhibitors such as febuxostat are a mainstay of therapy to help reduce blood urate levels in affected patients. A recent clinical trial published ...

Arthritis & Rheumatism

Study lays foundation for new psoriasis treatment strategy

About 250,000 people in Austria suffer from psoriasis. One third of them develop inflammation in their joints (psoriatic arthritis) as a result of the chronic skin condition. As part of a study, a MedUni Vienna research team ...

Arthritis & Rheumatism

Most common allergies not linked to rheumatoid arthritis

Most common allergies are not associated with the risk for rheumatoid arthritis (RA), but some allergic conditions, including animal dander allergy and atopic dermatitis, are associated with increased RA risk, according to ...