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Laboratory medicine news

Faster aging, chronic disease linked to WTC responders with PTSD

Post-traumatic stress disorder (PTSD) remains a common condition affecting World Trade Center (WTC) responders 25 years after the attack on the Twin Towers. While the condition is considered mainly psychological, a new study ...

GenAI overcomes slide misalignment to produce virtual stains close to real slides

Histopathology is a cornerstone of clinical diagnosis, especially in cancer care. However, conventional chemical staining is often time-consuming and labor-intensive and may consume precious tissue samples.

New framework renders AI more trustworthy for cancer subtyping

Medical artificial intelligence (AI) faces a fundamental challenge: uncertainty quantification. Artificial neural networks are largely unaware of the limits of their training data and can become overconfident when confronted ...

CT tissue images can now be virtually stained in 3D

Rudolf Virchow fundamentally changed medicine when he formulated his cell theory of disease in the 19th century: Diseases do not arise inexplicably within the organism, but rather in specific cells and tissues. To this day, ...

Therapeutic target for dangerous fungal infections identified

A multidisciplinary team of researchers at the University of Wisconsin–Madison has identified a promising new therapeutic candidate against Candida auris, an emerging fungal pathogen that has alarmed health officials worldwide ...

AI diagnoses brain tumors in minutes instead of weeks

Experts in Heidelberg, Germany, have developed an AI system that can classify brain tumors with unprecedented accuracy using standard microscopic tissue sections. Using digitized standard stains, the system identifies more ...

A skin biopsy can detect a rare neurodegenerative disease

By determining the structure of the deposits responsible for transthyretin amyloidosis through a simple skin biopsy, scientists at UNIGE are paving the way for a new diagnostic method for neurodegenerative diseases. Transthyretin ...

AI can predict preemies' paths based on blood spot data

An artificial intelligence-based tool can predict the medical trajectories of individual premature newborns from blood samples collected soon after they are born, a Stanford Medicine-led study has shown.

Virtual histography: From tissue section to 3D image

Histology is one of the foundations of modern diagnostics. When physicians want to determine whether tissue is pathologically altered, they rely on microscopic tissue analysis: They cut the tissue into ultrathin sections, ...