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Laboratory medicine news

Updated guidelines standardize how tumor response is measured after surgery

Researchers at the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have released updated consensus guidelines and an associated reproducibility study to standardize how pathologists ...

How our lab is helping develop an Alzheimer's test that can be done at home

Imagine diagnosing one of the most challenging neurological diseases with just a quick finger-prick, a few drops of blood and a test sent in the post. This may sound like science fiction, but we are hoping our research could ...

Early signs of Parkinson's can be identified in the blood

A team led by researchers at Chalmers University of Technology, Sweden, has succeeded in identifying biomarkers for Parkinson's disease in its earliest stages, before extensive brain damage has occurred. The biological processes ...

A skin biopsy can detect a rare neurodegenerative disease

By determining the structure of the deposits responsible for transthyretin amyloidosis through a simple skin biopsy, scientists at UNIGE are paving the way for a new diagnostic method for neurodegenerative diseases. Transthyretin ...

AI can predict preemies' paths based on blood spot data

An artificial intelligence-based tool can predict the medical trajectories of individual premature newborns from blood samples collected soon after they are born, a Stanford Medicine-led study has shown.

Virtual histography: From tissue section to 3D image

Histology is one of the foundations of modern diagnostics. When physicians want to determine whether tissue is pathologically altered, they rely on microscopic tissue analysis: They cut the tissue into ultrathin sections, ...

Simple urine test developed to screen bladder cancer

Researchers have discovered that analyzing specific patterns of cell-free DNA (cfDNA) fragmentation in a simple urine sample can effectively diagnose and stage bladder cancer, offering a much-needed alternative to invasive ...

Fibulin-5: A potential marker for liver fibrosis detection

When damage to the liver caused by alcohol or viral infections persists, liver fibrosis progresses and replaces tissue with collagen fibers. This is especially a risk in chronic hepatitis C patients, where liver fibrosis ...

What your sweat can reveal about your health

Sweat contains a wealth of biological information that, with the help of artificial intelligence and next-generation sensors, could transform how we monitor our health and well-being, a new study suggests.

Illicit diazepam tablets show wide strength variation

A study from King's, in collaboration with TICTAC Communications and Nanalysis, tested seized tablets containing the sedative diazepam and found considerable variation in strength and content, highlighting the dangers of ...

When ribosomes collide, cells launch emergency stress defenses

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the messenger molecule, reading the genetic code as they go. Using this information, they link amino acids ...

Pattern of chronic rejection for liver transplants decoded

Liver transplants often save the lives of seriously ill patients. However, there remains a risk that the body will reject the new organ. Doctors distinguish between acute and chronic rejection. While acute rejection is easy ...

AI tool spots blood cell abnormalities missed by doctors

An AI tool that can analyze abnormalities in the shape and form of blood cells, and with greater accuracy and reliability than human experts, could change the way conditions such as leukemia are diagnosed.