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Laboratory medicine news

New hantavirus sequencing tool maps whole genomes from hard-to-test samples

Infections by hantaviruses are rare but dangerous, killing 30–40% of infected people. When cases occur, public health officials need rapid, detailed information about the virus to identify the strain and its origin, so they ...

New medium offers faster, cheaper drug-resistance detection

A critical problem in treating Clostridioides difficile infections is the possibility that the pathogen develops resistance to fidaxomicin, an antibiotic often prescribed as a first-line treatment. But current methods used ...

Are you sleep deprived? Your spit may hold answer

Sleep loss dulls alertness and coordination, and it can produce effects similar to severe intoxication, making actions like driving incredibly risky. But there's no clinical test for determining when someone is dangerously ...

Can AI beat breast cancer?

An artificial intelligence (AI) system that combines breast cancer tissue images with molecular marker data achieves high accuracy in diagnosis, tumor classification, and survival prediction. Details of the research are reported ...

Blood test detects early signs of breast cancer recurrence

Researchers at Lund University have developed a blood test capable of detecting signs of breast cancer recurrence long before recurrence becomes visible on imaging or causes symptoms. It has previously been shown that this ...

A better way to see how brain cells falter in disease

To gain better insight into what's happening in the brain, researchers examine the molecules produced by brain cells, including RNA and proteins. But existing methods for molecular profiling don't always capture the cells' ...

New test identifies active, infectious form of tuberculosis

Researchers in the UC Davis Department of Pathology and Laboratory Medicine have created a new tuberculosis blood test that can detect the active, infectious form of the disease. The discovery enables faster diagnosis and ...

Bile acid and steroid signatures tied to extreme longevity

Centenarians often live to 100+ due to a combination of protective genetic factors, which account for up to 50%, and healthy lifestyles, such as plant-forward diets, regular, natural movement and strong social connections. ...

New biomarker for immunoglobulin A nephropathy identified

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced ...

How gene-targeting technology is transforming STI diagnosis

Most people who have heard of clustered regularly interspaced short palindromic repeats (more commonly known as CRISPR) associate it with gene editing—the precise molecular scissors that allow scientists to cut and rewrite ...

MetaRing quickly identifies breast cancer drug sensitivity

Recently, a research team led by Prof. Wang Hongzhi from the Hefei Institutes of Physical Science, Chinese Academy of Sciences, has developed a programmable plasmonic ring biosensor, MetaRing, capable of rapidly and accurately ...