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Laboratory medicine news

Biopsy-derived cryo-EM structures reveal patient-specific amyloid fibrils

Prof. Liu Cong from the Shanghai Institute of Organic Chemistry of the Chinese Academy of Sciences, along with collaborators, has revealed the high-resolution structures of amyloid fibrils directly extracted from biopsy samples ...

Stem cell expert Q&A: Innovative pathways in biomedical research

New scientific methods could one day render animal studies—the standard in research laboratories for more than 100 years—obsolete. Clive Svendsen, Ph.D., executive director of the Board of Governors Regenerative Medicine ...

Blood test reveals risk of multimorbidity in older adults

A small set of common blood biomarkers predicts which older adults will develop specific combinations of chronic diseases—and how quickly, according to a new study from Karolinska Institutet published in Nature Medicine.

Costs pose hurdle for promising new hepatitis C lab test

A new rapid test for hepatitis C could help identify many more patients who could be cured of the deadly disease, but its use may be limited unless insurers' reimbursement rises to cover its high cost, according to researchers ...

New ALS diagnostic blood test boasts 97% accuracy

ALS is a debilitating paralytic disease characterized as the death of upper and lower motor neurons. Fortunately, ALS is relatively rare, with an incidence rate of 1.6 per 100,000 adults, resulting in about 30,000 cases in ...

Your blood proteins could predict your risk of an early death

Imagine if a simple blood test could offer a glimpse into your future health. Not just whether you have heart disease or cancer today, but whether your overall risk of dying in the next five or ten years is higher or lower ...

3D genome mapping tool reveals hidden complexity in DNA

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new discoveries.

RNA tech could make fast test for Alzheimer's disease

One of the most frightening things about Alzheimer's disease is how difficult it is to diagnose early. Now, University of Connecticut researchers report two fast tests for early markers of the disease in the journal Biosensors, ...

AI tool beats humans at detecting parasites in stool samples

Scientists at ARUP Laboratories have developed an artificial intelligence (AI) tool that detects intestinal parasites in stool samples more quickly and accurately than traditional methods, potentially transforming how labs ...

Multiple sclerosis linked with distinct oral microbiome

With ads everywhere for pro- or pre-biotic foods and supplements, most people are familiar with the gut microbiome—the trillions of bacteria, fungi, and viruses that colonize our digestive tract—and the idea that keeping ...

Rethinking how bone marrow works with a unified framework

One huge reason why the world of medicine hasn't yet found "the cure" for hard-to-treat malignancies like acute myeloid leukemia (AML) and many other forms of cancer is that the world of science is still striving to fully ...

Simple urine test could transform kidney care

In a finding set to change the way disease is monitored, Chandra Mohan, an international expert and pioneer in lupus research at the University of Houston, is reporting that urine samples can indicate lupus nephritis in a ...

AI system delivers comprehensive cancer diagnosis

The Hong Kong University of Science and Technology (HKUST) today launched SmartPath, a comprehensive artificial intelligence (AI) system designed to transform the entire pathology workflow for cancer care.