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Laboratory medicine news

New approach cuts sepsis diagnosis from days to hours

Sepsis, a life-threatening condition that stems from the body trying to fight off an infection, plagues more than 1.5 million patients a year in the U.S. alone, with one in three deaths recorded in hospitals attributed in ...

AI matches human pathologists in predicting breast cancer outcomes from immune cells

Two major international Peter Mac-led studies have found AI models were just as good as human pathologists at a task that predicts outcomes for patients with breast cancer.

Wastewater may offer an early warning of pertussis outbreaks

Pertussis, or whooping cough, continues to cause periodic outbreaks worldwide and can be especially dangerous for infants who have not completed vaccination. Yet conventional surveillance depends on people seeking medical ...

Researchers find cold storage platelets safe and effective

A new study has found platelets kept in cold storage are as effective at treating bleeding and have a longer shelf life than platelets stored at room temperature. Dr. James Preuss and Dr. Warren Pavey, from The University ...

New rapid test could transform iron treatment worldwide

Iron deficiency is one of the world's most common nutritional disorders, affecting millions of women and children globally. Yet diagnosing it remains difficult in many low-resource settings, where access to laboratories and ...

Improving the diagnosis of primary aldosteronism

A simple new method based on the results of two studies from Christofer Juhlin's research group can make it easier to identify the underlying cause of a common form of high blood pressure and help predict who will benefit ...

Blood test may help guide treatment for metastatic melanoma

A blood test that measures how quickly tumor cells divide could in the future help doctors assess prognosis and select treatment strategies for patients with melanoma that has spread to other parts of the body. This is shown ...

ULTRA maps glioma margins in 3D within 30 minutes

One of the major challenges in glioma surgery is that tumor boundaries are often difficult to define. Diffuse gliomas can infiltrate surrounding brain tissue beyond what surgeons can see directly or what conventional imaging ...

AI maps tumor cells that may seed later metastases

A cancerous tumor is not a single enemy. It is made up of many different cell populations that can behave in very different ways. Among them, even at the time of diagnosis, there may already be cells that months or years ...

How a louse-borne pathogen evades the immune system

Louse-borne relapsing fever is caused by the spirochete bacterium Borrelia recurrentis, which is transmitted by body lice (not head lice). The disease was first described by Hippocrates (460–370 B.C.). Initial symptoms include ...

New medium offers faster, cheaper drug-resistance detection

A critical problem in treating Clostridioides difficile infections is the possibility that the pathogen develops resistance to fidaxomicin, an antibiotic often prescribed as a first-line treatment. But current methods used ...

Are you sleep deprived? Your spit may hold answer

Sleep loss dulls alertness and coordination, and it can produce effects similar to severe intoxication, making actions like driving incredibly risky. But there's no clinical test for determining when someone is dangerously ...

Can AI beat breast cancer?

An artificial intelligence (AI) system that combines breast cancer tissue images with molecular marker data achieves high accuracy in diagnosis, tumor classification, and survival prediction. Details of the research are reported ...

Blood test detects early signs of breast cancer recurrence

Researchers at Lund University have developed a blood test capable of detecting signs of breast cancer recurrence long before recurrence becomes visible on imaging or causes symptoms. It has previously been shown that this ...