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Oncology news

Ketone supplementation improves immunotherapy outcomes in mice, with human clinical trial underway

A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 in the journal Cell, ...

Wnt signaling drives stomach cancer spread by reshaping surrounding tissue, finds study

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs. Their study ...

Overcoming ovarian cancer's resistance to immunotherapy

Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors. Different forms ...

Light-sensing genes may connect three childhood tumor types

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St. Jude Children's Research ...

Study maps US diabetes–cancer hotspots

A new University of Kentucky study has mapped areas across the U.S. where high rates of diabetes and deaths from diabetes-related cancers overlap. The UK Markey Cancer Center and Barnstable Brown Diabetes Center research ...

GI cancers to double by 2050, experts warn

Gastrointestinal cancer cases are expected to double worldwide by 2050, according to a multi-institutional study co-led by Cedars-Sinai. The projections, based on 2022 data and published in the journal Cancer, conclude that ...

New AI tool predicts best pancreatic cancer treatment

A new tool co-developed by investigators from Cedars-Sinai Health Sciences University can predict which of two available chemotherapy options for pancreatic cancer would be more effective for an individual patient.

Open source cancer database created for easier disease study

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data—including ...

A genetic blueprint for avoiding killer T cell exhaustion

A multi-institutional study led by researchers at UNC Lineberger Comprehensive Cancer Center, the Salk Institute for Biological Studies, and UC San Diego has uncovered new genetic rules that determine how powerful immune ...

A reliable atlas of cell types found in breast cancers

Breast cancer (BC) is the most common cancer and the second leading cause of cancer death in women. It is a highly variable disease, defined as a malignancy of the epithelial ducts in breast tissue. Characterizing the vast ...

Could fecal transplants be the new way to fight cancer?

One person's waste could be another's shot at fighting cancer. The idea may sound far-fetched, but it is gaining momentum in cancer care. Researchers are testing fecal microbiota transplants as a way of changing the gut's ...

Epigenetic therapy could 'switch off' cancer genes for good

Monash University researchers, in collaboration with Harvard University, have discovered how to permanently "switch off" cancer-causing genes, revealing a new approach to cancer treatment. The breakthrough, published in the ...

A fungus living in our body can make melanoma more aggressive

Cancer is one of the causes responsible for the most deaths worldwide. In 2020, for example, it resulted in ten million deaths. It has been estimated that microorganism infections caused between 13 and 18% of these cases. ...

Protein identified as cause of skin damage after radiotherapy

Radiotherapy is one of the main treatment forms for cancer. Among its most common side effects is skin damage, right up to chronic inflammation and fibroses. At present, such long-term damage can only be treated symptomatically ...

Four out of every 10 cancer cases are preventable: WHO

Nearly four out of every 10 cancer cases could be prevented if people avoided a range of risk factors including smoking, drinking, air pollution and certain infections, the World Health Organization said Tuesday.