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Oncology news

Same-day chemotherapy boosts cancer vaccine responses in preclinical models

Both the clinical effects and the unpleasant side effects of chemotherapies, from hair loss to mouth sores to gastrointestinal discomfort, stem from their indiscriminate destruction of cells prone to rapid proliferation. ...

Inflammation can reactivate 'sleeping' cancer cells hidden in the bone

The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest challenges in cancer treatment and is responsible for most cancer-related deaths.

How to manage the side effects of radiation therapy

Many of us know someone who's faced side effects of cancer treatment, like hair loss or debilitating nausea. Their experiences can make us wonder whether everyone experiences these same effects.

Developing sustainable printing inks for functional organs

The organ transplant waiting list numbers 8,000 people each year in Germany alone, and about 10% of them never receive an organ. 3D bioprinting could help address the global shortage of donor organs by making it possible ...

Study finds hidden mutation rates may shape cancer risk

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study participants had mutation ...

How pneumonia can reveal undiagnosed blood cancer

Severe pneumococcal disease requiring hospitalization, most commonly pneumonia, can be a sign of previously undiagnosed blood cancer and immunodeficiency in adult patients, according to a study from the University of Gothenburg.

Mini-tumors reveal new drug combinations for liver cancer

Liver cancer is difficult to treat because tumors vary greatly from patient to patient. Researchers at the University of Basel have captured this diversity by creating a collection of mini-tumors, which they use to systematically ...

Supplement plus chemotherapy boosts pancreatic cancer survival

When added to standard chemotherapy, a clinical version of the dietary supplement L-glutamine improved survival in an early-phase trial of patients with advanced pancreatic cancer. The study, led by Cedars-Sinai Health Sciences ...

How melanoma silences the skin's natural antitumor defense

Cancers actively remodel their surrounding cells and tissues to create a microenvironment that favors their growth, survival and spread. Melanoma, a cancer of the pigment-producing melanocytes of the skin, is one of the most ...

Protein buildup may shape cancer drug response

The way cancer-causing proteins accumulate in tumors may influence how effectively a promising new generation of medicines can remove them, a study suggests. Researchers found that PROTAC (Proteolysis Targeting Chimeras) ...