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Oncology news

Preoperative chemo and immunotherapy combo shrinks head, neck cancer tumors

Combining chemotherapy with immunotherapy before surgery for head and neck cancer is associated with significantly greater reductions in tumor size than immunotherapy alone, according to a study published online Aug. 13 in ...

How loss of tumor suppressor drives ER+ breast cancer to metastasize to the bone

A Baylor College of Medicine-led team has uncovered how loss of tumor suppressor neurofibromin (NF1) in estrogen receptor-positive (ER+) breast cancer cells drives the cells' preference to metastasize to bone.

Exploring precision medicine for pancreatic cancer

Imagine if, before starting cancer care, doctors could rapidly identify the most effective chemotherapy, immunotherapy or combination to personalize treatment for a loved one's hard-to-treat pancreatic cancer and improve ...

A unified framework to explain one of cancer's major drivers

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, Ph.D., associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham ...

How 'undead' cells trigger cancer-promoting inflammation

Stopping tumor growth is only half the battle. Rather than killing tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells ...

How highly aggressive colon cancer evades the immune system

Researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have identified a previously unknown mechanism by which a particularly aggressive form of colon cancer evades the immune system.

Math and medicine join forces to solve a cancer mystery

Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body's immune system to identify and kill cancer cells ...

Newly found 'immune organ' inside skull directs brain defense

Researchers at Washington University School of Medicine in St. Louis have discovered lymph node-like structures in the skull bone marrow of mice for the first time and demonstrated that they act as rapid first responders ...

New cancer drug shows promise in mesothelioma trial

Mesothelioma is a rare but aggressive cancer, usually caused by exposure to asbestos. Inhaled asbestos fibers become lodged in the lungs, causing inflammation that can lead to tumor formation decades later. Worldwide, about ...

For your health—can your breakfast help lower cancer risk?

Don't sleep on the cancer prevention benefits of a healthy breakfast. Whether it's oatmeal, whole-wheat toast, berries in Greek yogurt or other healthy combinations—starting the morning with simple, whole foods is a great ...

Immunotherapy shows long-term promise in aggressive lymphoma

A leading-edge immunotherapy may extend survival for patients with one of the most aggressive forms of blood cancer, according to newly published five-year results from a major clinical trial in the Blood Journal. The clinical ...

KRAS-targeting drugs show promise for rare appendix cancer

Targeting mutant KRAS may offer a promising new treatment option for appendix cancer, according to research from The University of Texas MD Anderson Cancer Center published in the Journal of Hematology & Oncology.

Novel technology could aid targeted lung cancer treatment

Scientists have developed a new method for accurately predicting gene changes that cause lung cancer, without the need for slower, more expensive lab techniques. The technology was able to identify specific genetic changes ...