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Oncology news
Study maps complex interplay between cells, metabolism, and immunity in breast cancer lymph node metastasis
A recent integrative analysis of single-cell sequencing and single-cell spatial mapping of lymph node metastasis in breast cancer reveals novel mechanisms of the metabolic-immune interaction that drive the spread of breast ...
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Ketone supplementation improves immunotherapy outcomes in mice, with human clinical trial underway
A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 in the journal Cell, ...
18 hours ago
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Wnt signaling drives stomach cancer spread by reshaping surrounding tissue, finds study
Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs. Their study ...
21 hours ago
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Robotic surgery removes hard-to-reach caudate lobe tumor in a 79-year-old
Resection of tumors in the caudate lobe (a deep, hard-to-reach part of the liver) is recognized as one of the most technically challenging procedures in hepatic surgery due to its unique anatomical position and complex vascular ...
21 hours ago
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Blood-based marker opens up perspectives for cancer diagnostics
Metastatic prostate cancer is currently associated with high morbidity and mortality rates. In addition, patients respond very differently to standard treatments such as hormone therapy or radiation therapy. Reliable markers ...
17 hours ago
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Cancer has a unique nuclear metabolic fingerprint, researchers discover
More than 200 metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published in Nature Communications. The ...
Mar 6, 2026
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AI blood test detects early pancreatic cancer with up to 94% accuracy
A team of researchers from Taiwan has developed PanMETAI, an AI-powered platform that analyzes metabolic fingerprints in a simple blood sample to detect pancreatic cancer at its earliest stages—when treatment is most effective—achieving ...
Mar 5, 2026
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Overcoming ovarian cancer's resistance to immunotherapy
Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors. Different forms ...
Mar 5, 2026
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Light-sensing genes may connect three childhood tumor types
Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St. Jude Children's Research ...
Mar 5, 2026
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Combination therapy shows promising efficacy in aggressive leukemia
Acute myeloid leukemia (AML) is a particularly aggressive form of blood cancer that usually progresses rapidly if swift and intensive treatment is not applied. Although the disease can often be contained by chemotherapy (remission), ...
Mar 5, 2026
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Study points to potential new therapies for hard-to-treat lung cancers
Findings from a study led by researchers at The Ohio State University Comprehensive Cancer Center–Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC–James) support the potential of new therapies ...
Mar 5, 2026
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MRI supplemental to digital breast tomosynthesis averts additional breast cancer deaths
For women aged 40 years and older with extremely dense breasts, digital breast tomosynthesis (DBT) with supplemental magnetic resonance imaging (MRI) averts additional breast cancer deaths and results in more false-positive ...
Mar 5, 2026
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AAAAI: No increase seen in asthma exacerbations with ICI use for melanoma, renal cell carcinoma
For patients with asthma, receipt of immune checkpoint inhibitor (ICI) therapy for melanoma or renal cell carcinoma is not associated with an increased risk for exacerbations, according to a study presented at the annual ...
Mar 5, 2026
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No decline in childhood cancer survival in Sweden during the pandemic
During the COVID-19 pandemic, there were global concerns that children with cancer might experience delayed diagnoses and disruptions to treatment, which in turn could worsen prognosis. However, a new register-based study ...
Mar 5, 2026
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Cryotherapy could be a game changer for patients with early-stage kidney cancer
Today, small kidney tumors are most often treated with a minor operation in which all or part of the kidney is removed. However, in many cases, these small tumors can be treated with targeted cryotherapy, which destroys the ...
Mar 5, 2026
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Study maps US diabetes–cancer hotspots
A new University of Kentucky study has mapped areas across the U.S. where high rates of diabetes and deaths from diabetes-related cancers overlap. The UK Markey Cancer Center and Barnstable Brown Diabetes Center research ...
Mar 5, 2026
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GI cancers to double by 2050, experts warn
Gastrointestinal cancer cases are expected to double worldwide by 2050, according to a multi-institutional study co-led by Cedars-Sinai. The projections, based on 2022 data and published in the journal Cancer, conclude that ...
Mar 5, 2026
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Molecular target drives immunogenicity in cancer immunotherapy
Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as a potential "switch" that can modulate a type of cancer cell death known as immunogenic cell death ...
Mar 5, 2026
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AI could help predict your risk of breast cancer in the next four years
An artificial intelligence (AI) algorithm used to detect breast cancer in screening scans has been adapted into a risk score that estimates a woman's risk of developing breast cancer over the next four years, according to ...
Mar 4, 2026
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Engineered CAR-T cells block key protein to break solid tumors' immune shield
UCLA scientists have developed a next-generation CAR-T cell therapy that can overcome the immunosuppressive tumor microenvironment, a protective shield that tumors use to weaken immune cells, block their attack, and fuel ...
Mar 4, 2026
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Why some tiny tumors vanish and others grow: Discovery could help treat cancer at very earliest stages
Cambridge scientists have shown that when tumors first emerge, interactions with healthy cells in the underlying supportive tissue determine their ability to survive, grow, and progress to advanced stages of disease.
Mar 4, 2026
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Good vibrations: Playing music to cells reduces laryngeal cancer aggressiveness in lab tests
The continuous movement of the vocal cords weakens and eventually stops as laryngeal cancer progresses. Researchers have, for the first time, discovered that restoring cellular vibration reduces the aggressiveness of advanced ...
Mar 4, 2026
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An existing, FDA-approved drug could stem the spread of breast cancer
Cancer spreads (metastasizes) when tumor cells shed from a primary solid tumor (for example, in the breast) and embed in other organs, such as the lung, liver, and brain, and begin to grow. Most approaches to prevent this ...
Mar 4, 2026
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New AI tool predicts best pancreatic cancer treatment
A new tool co-developed by investigators from Cedars-Sinai Health Sciences University can predict which of two available chemotherapy options for pancreatic cancer would be more effective for an individual patient.
Mar 4, 2026
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One-hour saliva test spots biomarker linked to several cancers
QUT researchers have developed a simple one-hour saliva test for a protein biomarker that has been linked with oral, colon and pancreatic cancers. The findings are published in the journal Talanta.
Mar 4, 2026
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