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Oncology news

The 'zombie cell' effect: New study explains chemotherapy resistance in lung and ovarian cancers

Researchers have identified a biological mechanism that helps explain why some lung and ovarian cancers become resistant to chemotherapy, offering insight into why cancers recur. The study, published in Nature Aging this ...

How pancreatic cancer prepares the tumor environment: A possible biomarker for the earliest stage of development

Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment and creates an inflammatory and immune-defensive microenvironment in which the carcinoma can grow. ...

Cancer cell study sheds light on cachexia's origins

New research from the University of Oklahoma, published today in Cancer Cell, describes for the first time a "triangle regulation theory" of cancer-induced cachexia and anorexia. Cachexia is a muscle-wasting and fat-loss ...

New characteristics of aggressive prostate cancer identified

For the first time ever, NTNU researchers have identified new characteristics of aggressive prostate cancer. The research lays a foundation for the possibility that aggressive prostate cancer can probably be detected through ...

Rallying more T-cells to immunotherapy's fight against cancer

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...

New research results in changes to NHS guidelines

Hundreds of people with advanced bladder cancer across the UK can now receive three rather than six chemotherapy cycles following research by Queen Mary University of London which has led to a change to NHS treatment guidelines. ...

Pancreatic cancer: Warning signs to heed

Your pancreas has important jobs to do. A large gland behind the lower part of the stomach, it produces hormones that regulate blood sugar and enzymes that help digest food. What if it develops cancer?

Established cancer drug can reactivate immunotherapy

Genetically modified immune cells can offer precious additional time to patients with advanced multiple myeloma. However, these therapies lose their impact as the molecules on cancer cells that immune cells recognize gradually ...

Many head and neck cancer trials end early. Why?

Head and neck cancer trials are frequently derailed before they can deliver answers. A new analysis suggests that the most common reasons are sponsor decisions related to safety or effectiveness and poor patient recruitment.

How aggressive breast cancer controls protein production

A previously unknown mechanism that makes it possible for aggressive so-called triple-negative breast cancer to fine-tune its production of proteins has been discovered by researchers at Umeå University, Sweden. The discovery ...

New model improves prediction of prostate cancer death risk

A new long-term prediction tool estimates the risk of dying from prostate cancer, offering a more accurate way to interpret prostate-specific antigen (PSA) test results compared to existing models. The tool, tested on over ...

New vulnerability identified in aggressive breast cancer

Researchers at University of California San Diego have identified a previously unrecognized treatment target for triple‑negative breast cancer (TNBC), the most aggressive subtype of breast cancer. Their new study reveals ...