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Oncology & Cancer news
Oncology & Cancer
Lymph nodes found to be key to successful cancer immunotherapy
A team of researchers, led by the Peter Doherty Institute for Infection and Immunity (Doherty Institute), explored the cellular and molecular interactions revealing how lymph nodes play a crucial role in the fight against ...
22 hours ago
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Oncology & Cancer
Investigating how tumor-immune cell clusters drive breast cancer spread
In a pair of studies, investigators from the lab of Huiping Liu, MD, Ph.D., associate professor of Pharmacology and of Medicine in the Division of Hematology and Oncology, have uncovered how specific cellular interactions ...
19 hours ago
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Scientists find cell surface sugar that slows pancreatic cancer in mice—and it's detectable in patient blood samples
Pancreatic cancer has the highest mortality rate of all major cancers, and its incidence is climbing. Because it is typically asymptomatic at early stages, pancreatic cancer is especially difficult to catch and treat in time. ...
20 hours ago
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Stronger together: A new fusion protein boosts cancer immunotherapy
A newly developed molecule brings together two powerful immunotherapy strategies in one treatment. Researchers at the University of Basel and University Hospital Basel, Switzerland, have demonstrated that this fusion protein ...
20 hours ago
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AI model indicates four out of ten breast cancer patients could avoid axillary surgery
A project at Lund University in Sweden has trained an AI model to identify breast cancer patients who could be spared from axillary surgery. The model analyzes previously unutilized information in mammograms and pinpoints ...
20 hours ago
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Subtle cues between cells and immune system can contribute to spread of cancer
In the march of metastasis, a molecular trail of crumbs guides some cancer cells from the primary tumor to establish new colonies within the body. Blocking the cells' ability to follow the trail might halt metastasis but ...
20 hours ago
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Algorithm that predicts pancreatic cancer metastasis could help avoid unnecessary surgeries
Pancreatic cancer remains one of the biggest challenges in the field of oncology. Numbers of cases are increasing, and the latest personalized therapies and immunotherapy are not yet yielding results. Much of the effort is ...
18 hours ago
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Blocking CNNM4 protein with RNA technology could treat rare and aggressive liver cancer
An international study led by Dr. Malu Martínez-Chantar, principal investigator at CIC bioGUNE and CIBERehd, has identified a new therapeutic target for cholangiocarcinoma (CCA), a rare but highly aggressive liver cancer ...
19 hours ago
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Lactate-driven protein modification weakens natural killer cell cancer defenses
A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen's team from Human Phenome Institute at Fudan University, has elucidated ...
19 hours ago
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Reprogramming the epigenetic code affects growth and survival of tumor cells in multiple myeloma
In the cancer type multiple myeloma, the malignant cells differ significantly from normal cells regarding the layer of chemical "tags" on DNA and proteins that control whether genes are turned on or off. These "tags" affect ...
19 hours ago
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Basal stem-like cells identified as origin of small cell lung cancer in lab models
A new study reveals that small cell lung cancer (SCLC) likely begins in basal stem-like cells rather than in neuroendocrine cells, marking a major shift in the understanding of this aggressive disease that is often associated ...
19 hours ago
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NONO molecules block immune system defenses against breast cancer, so researchers switched it off
A new study has identified a potential new target for treating triple-negative breast cancer, one of the most aggressive forms of breast cancer, which still has very few therapeutic options available. The study was carried ...
21 hours ago
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Targeted radiation therapy shows near-complete response in rare sarcoma patients
A novel targeted radiation approach for a rare form of malignant tumor—the solitary fibrous tumor (SFT)—has shown significant success, achieving a near-complete response in three patients. The therapy significantly reduced ...
17 hours ago
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Remote monitoring can improve recovery from cancer surgery
A new study co-authored by Tracy Crane, Ph.D., RDN, co-leader of the Cancer Control Program at Sylvester Comprehensive Cancer Center, part of the University of Miami Miller School of Medicine, shows that remote perioperative ...
17 hours ago
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Your immune system attacks drugs like it does viruses, paradoxically offering a way to improve cancer treatment
When the first cells appeared on Earth approximately 3.8 billion years ago, viruses were already here to greet them. Ever since, viruses have been devising ways to infect cells, and cells have been responding by evolving ...
21 hours ago
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'Molecular glue' harnesses the power of the immune system to treat neuroblastoma
Gene expression governs whether neuroblastoma tumor cells exist in either the adrenergic (differentiated and sensitive to treatment) or mesenchymal (less differentiated and therapy-resistant) cell state. Tumors may switch ...
Sep 17, 2025
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New personalized risk score could improve ovarian cancer detection
Researchers from Queen Mary University of London have developed and validated a new tool that could help GPs detect ovarian cancer earlier and improve patient outcomes cost-effectively.
Sep 17, 2025
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Blood test to rule out esophageal cancer
Proteomics International has launched PromarkerEso at the ISDE World Congress in Brisbane (18–20 September). PromarkerEso is a world-first protein biomarker-based blood diagnostic that can rule out esophageal adenocarcinoma ...
Sep 17, 2025
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Getting the facts on ovarian cancer
Ovarian cancer is relatively rare. However, it's often fatal in later stages of the disease. The cancer begins in the ovaries and spreads to the abdomen and pelvis if it isn't diagnosed and treated early. It primarily affects ...
Sep 17, 2025
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Promising preclinical therapy exploits ALK protein to selectively destroy tumors while sparing healthy cells
Researchers at Children's Hospital of Philadelphia (CHOP) unveiled a novel antibody-drug conjugate (ADC) that shows striking efficacy against cancers that express the anaplastic lymphoma kinase (ALK) protein on the cancer ...
Sep 16, 2025
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Two-part prodrug system activates immune attack only in tumor's unique environment
Scientists have developed a smarter way to activate the immune system against cancer, potentially making treatments safer and more precise.
Sep 16, 2025
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Promising drug combinations for immunotherapy-resistant melanoma may also help reactivate immune system
Researchers at Sutter's California Pacific Medical Center (CPMC) in San Francisco, Calif. have identified potential new therapeutic strategies for patients with advanced melanoma who no longer respond to immunotherapy—an ...
Sep 16, 2025
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Lymph node study reveals how aggressive breast cancer evades immune detection
In almost all solid tumors—i.e. cancers with a solid tissue structure—the detection of tumor cells in the lymph nodes is considered a decisive marker for the progression of the disease. Lymph node involvement has a significant ...
Sep 16, 2025
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Integrated metabolic analysis reveals cancer's energy secrets
A research group led by The University of Osaka has developed a novel method for analyzing cancer metabolism, revealing new insights into cancer's inefficient energy process.
Sep 16, 2025
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Bout of cystitis may signal presence of urogenital cancers in middle-aged adults
A bout of the common bladder infection, cystitis, may signal the presence of urogenital cancers—which affect parts of the body involved in reproduction and excretion—in middle-aged adults, suggests research published ...
Sep 16, 2025
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