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Oncology news
Preoperative chemo and immunotherapy combo shrinks head, neck cancer tumors
Combining chemotherapy with immunotherapy before surgery for head and neck cancer is associated with significantly greater reductions in tumor size than immunotherapy alone, according to a study published online Aug. 13 in ...
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Cancer drug strategy flips script: PRMT1 activator boosts chemotherapy in pancreatic cancer mouse study
What if we could fight cancer by specifically activating a key enzyme instead of deactivating it? That's exactly what a research team at Marburg University has achieved for the first time with the enzyme PRMT1. The scientists ...
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How loss of tumor suppressor drives ER+ breast cancer to metastasize to the bone
A Baylor College of Medicine-led team has uncovered how loss of tumor suppressor neurofibromin (NF1) in estrogen receptor-positive (ER+) breast cancer cells drives the cells' preference to metastasize to bone.
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Lung cancer patient becomes tumor-free after treatment with selenite
A patient with advanced, treatment-resistant lung cancer became tumor-free after treatment with the selenium compound selenite. This is shown in a new study from Karolinska University Hospital and Karolinska Institutet published ...
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New drug combination may help treat advanced prostate cancer
About 1 in 8 men are diagnosed with prostate cancer during their lifetime. Although many survive, it can develop into metastatic disease.
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In cancer clinical trials, federal and industry sponsors play complementary roles
A comparative study of the cancer clinical trial portfolios supported by federal funding versus industry funding reveals they have distinct, interdependent roles in cancer research.The work, "Federal and Industry Sponsorship ...
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Drugs developed in China reaching international markets, research finds
China has become an increasingly important contributor to pharmaceutical development, but comparatively little attention has been paid to how successfully medicines developed in China have entered major international markets.
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Study shows lack of awareness for lung cancer screenings across country
Lung cancer screenings can save lives by detecting cancer in its early stages, but only 15% of eligible American adults have discussed the screening with their doctors, according to data analysis performed by University of ...
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Study points to broader stem cell donor options for blood cancer patients
For decades, stem cell transplantation has operated under a simple rule: The closer the donor match, the better. Patients with leukemia, lymphoma, myelodysplastic syndromes and other blood cancers often faced an extensive ...
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Exploring precision medicine for pancreatic cancer
Imagine if, before starting cancer care, doctors could rapidly identify the most effective chemotherapy, immunotherapy or combination to personalize treatment for a loved one's hard-to-treat pancreatic cancer and improve ...
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A unified framework to explain one of cancer's major drivers
In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, Ph.D., associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham ...
19 hours ago
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Lung tumor bacteria plus vitamin B2 metabolite may boost immune response to cancer
Bacteria in lung tumors may boost the activation of innate immune cells in the presence of a common vitamin metabolite, according to a preclinical study by researchers from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel ...
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Chemotherapy-free treatment shows promise for some patients with metastatic breast cancer
Researchers at the Icahn School of Medicine at Mount Sinai found that a chemotherapy-free combination of four targeted therapies showed encouraging results in patients with HR-positive, HER2-positive metastatic breast cancer, ...
22 hours ago
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How 'undead' cells trigger cancer-promoting inflammation
Stopping tumor growth is only half the battle. Rather than killing tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells ...
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How highly aggressive colon cancer evades the immune system
Researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have identified a previously unknown mechanism by which a particularly aggressive form of colon cancer evades the immune system.
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Colorectal cancer screening could reduce mortality by over 40%
People who take part in screening for colorectal cancer may have as much as a 43% lower risk of dying from the disease, according to new estimates published in JAMA Network Open by researchers at Karolinska Institutet and ...
Aug 20, 2026
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'Molecular glue' redirects a cancer-driving protein to activate cell death
A two-headed molecule designed by Stanford Medicine researchers hijacks one of the most common protein drivers of B-cell lymphoma, flipping it from its role as a promoter of cell growth into an arbiter of cell death. In mice, ...
Aug 20, 2026
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Simple mouth rinse may help detect stomach and colorectal cancer signals
It's widely understood that the microbiome—especially microbes found in the mouth and the gut—can have a profound effect on health. In a study published in the journal Cell Host & Microbe on Aug. 20, researchers report that ...
Aug 20, 2026
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Prostate cancer hijacks amino acid metabolism to signal hormone therapy resistance
Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may fuel hormone therapy resistance, according to a study by Weill Cornell Medicine investigators.
Aug 20, 2026
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Math and medicine join forces to solve a cancer mystery
Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body's immune system to identify and kill cancer cells ...
Aug 20, 2026
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Researchers estimate cancer risk in patients with pancreatic cysts, advancing early detection
Mayo Clinic researchers have estimated the risk that pancreatic cysts with worrisome or high-risk features will progress to pancreatic cancer or advanced precancerous changes within three years. The findings, published in ...
Aug 20, 2026
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Colorectal cancer may quietly damage nerves prior to chemotherapy
Researchers at The University of Texas MD Anderson Cancer Center found that, in preclinical models of colorectal cancer, tumors can start damaging peripheral nerves before chemotherapy begins. These findings suggest tumor-related ...
Aug 20, 2026
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Cabin crew at greater risk of radiation‑based cancer than nuclear technologists, new study suggests
What jobs are most associated with deaths from radiation-related cancer? Surprisingly, the answer is cabin crew and pilots—ahead of nuclear technologists, whose work involves handling radioactive materials used in medical ...
Aug 20, 2026
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Efficacy of a structured rehabilitation program for terminally ill cancer patients
Maintaining activities of daily living (ADLs) is important for terminally ill cancer patients, and dependency is associated with psychological distress. However, evidence for rehabilitation remains scarce in this setting.
Aug 20, 2026
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Human multi-organ chip tracks breast cancer spread to bone and lung
Cancer spreading beyond the primary tumor—a process known as metastasis—is responsible for at least two-thirds of cancer deaths. Drugs targeting metastatic progression have largely failed, in part because of the lack of predictive ...
Aug 19, 2026
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