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Oncology & Cancer news

Oncology & Cancer

AI model predicts B cell reactivity to neoantigens for improved cancer vaccines

Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move beyond one-time attacks and short-term memory to become a long-term immunity that "remembers" cancer, ...

Oncology & Cancer

Combination therapy for Burkitt's lymphoma dramatically improves cure rates in mice

Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most often in children and young adults. In recent years, CAR-T cell therapy—often referred to as a "living ...

Oncology & Cancer

Study finds a better way to screen for breast cancer

A pioneering study has found that an individualized approach to breast cancer screening that assesses patients' risk, rather than annual mammograms, can lower the chance of more advanced cancers, while still safely match ...

Oncology & Cancer

How stomach cancer learns to grow on its own

Gastric (stomach) cancer remains one of the most common and deadly cancers in East Asia, including Korea. Yet despite its high prevalence, it has received far less molecular attention than colorectal cancer, which is more ...

Oncology & Cancer

Stiffer colon could signal risk of early-onset colorectal cancer

Increased stiffness of the colon, spurred by chronic inflammation, may encourage the development and progression of early-onset colorectal cancer (CRC), a study co-led by UT Southwestern Medical Center researchers suggests. ...

Oncology & Cancer

Inflammation fuels one of the most aggressive forms of lung cancer

Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only 5%. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy. However, patients ...

Oncology & Cancer

Protein MCL1 links cancer cell survival and energy metabolism

A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology. Published in Nature Communications, the study shows for ...

Oncology & Cancer

How brain tumor cells influence neurons and vice versa

Gliomas are cancers that originate directly in the brain, instead of spreading to the brain from other parts of the body. These cancers cannot be cured with conventional cancer treatments, as they spread into healthy brain ...

Oncology & Cancer

Nanovaccine shows great promise for treating HPV-related cancers

A nanoparticle vaccine designed to fight cancers induced by human papillomavirus (HPV) eradicated tumors in an animal model of late-stage metastatic disease, UT Southwestern Medical Center scientists report in a new study ...

Oncology & Cancer

Father–son team integrates AI into cancer research

For more than three decades, USF Distinguished University Professor Dmitry Goldgof in the Bellini College of Artificial Intelligence, Cybersecurity and Computing has been at the forefront of artificial intelligence research. ...

Oncology & Cancer

AI model powers skin cancer detection across diverse populations

Researchers at the University of California San Diego School of Medicine have developed a new approach for identifying individuals with skin cancer that combines genetic ancestry, lifestyle and social determinants of health ...

Oncology & Cancer

T cell therapies show long-term HPV gains

Researchers from Rutgers Cancer Institute, New Jersey's only National Cancer Institute (NCI)—designated Comprehensive Cancer Center, and RWJBarnabas Health, along with colleagues from the National Cancer Institute, a center ...

Oncology & Cancer

Racial differences and prostate cancer treatment decisions

Black men choose aggressive prostate cancer treatment—regardless of anticipated life expectancy—more often than Hispanic or Caucasian men, according to new research by Cedars-Sinai investigators published in the journal ...

Oncology & Cancer

Promising drug can inhibit aggressive breast cancer

New research reveals a drug developed by scientists at Oregon Health & Science University may develop into a new treatment for an especially aggressive form of breast cancer.

Oncology & Cancer

How colorectal cancer evades immunotherapy using a dual barrier

Colorectal cancer is one of the leading causes of cancer death worldwide. In recent years, immunotherapies—treatments that reactivate the immune system to attack tumor cells—have transformed the treatment of many types ...