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Oncology news

Inflammation can reactivate 'sleeping' cancer cells hidden in the bone

The spread of cancer from a primary tumor to another place in the body, called metastasis, remains one of the greatest challenges in cancer treatment and is responsible for most cancer-related deaths.

Same-day chemotherapy boosts cancer vaccine responses in preclinical models

Both the clinical effects and the unpleasant side effects of chemotherapies, from hair loss to mouth sores to gastrointestinal discomfort, stem from their indiscriminate destruction of cells prone to rapid proliferation. ...

How to manage the side effects of radiation therapy

Many of us know someone who's faced side effects of cancer treatment, like hair loss or debilitating nausea. Their experiences can make us wonder whether everyone experiences these same effects.

Developing sustainable printing inks for functional organs

The organ transplant waiting list numbers 8,000 people each year in Germany alone, and about 10% of them never receive an organ. 3D bioprinting could help address the global shortage of donor organs by making it possible ...

Study finds hidden mutation rates may shape cancer risk

A new study by scientists at City of Hope and TGen, part of City of Hope, found surprisingly large differences in the number of mutations present in the organs of healthy individuals. Some study participants had mutation ...

How pneumonia can reveal undiagnosed blood cancer

Severe pneumococcal disease requiring hospitalization, most commonly pneumonia, can be a sign of previously undiagnosed blood cancer and immunodeficiency in adult patients, according to a study from the University of Gothenburg.

Exploring precision medicine for pancreatic cancer

Imagine if, before starting cancer care, doctors could rapidly identify the most effective chemotherapy, immunotherapy or combination to personalize treatment for a loved one's hard-to-treat pancreatic cancer and improve ...

A unified framework to explain one of cancer's major drivers

In a rare pair of papers published back-to-back in the journal Genes & Development, research teams led by senior author Anindya Bagchi, Ph.D., associate professor in the Cancer Genome and Epigenetics Program at Sanford Burnham ...

How 'undead' cells trigger cancer-promoting inflammation

Stopping tumor growth is only half the battle. Rather than killing tumor cells, many cancer therapies can only push them into cellular senescence, a state in which cells stop dividing but do not die. These "undead" cells ...

How highly aggressive colon cancer evades the immune system

Researchers from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have identified a previously unknown mechanism by which a particularly aggressive form of colon cancer evades the immune system.

Math and medicine join forces to solve a cancer mystery

Immunotherapy has transformed outcomes for many cancer patients. Unlike conventional treatments, these therapies do not attack tumors directly. Instead, they enable the body's immune system to identify and kill cancer cells ...