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Oncology & Cancer news
Oncology & Cancer
AI model predicts B cell reactivity to neoantigens for improved cancer vaccines
Neoantigens are unique markers that distinguish only cancer cells. By adding B cell reactivity, cancer vaccines can move beyond one-time attacks and short-term memory to become a long-term immunity that "remembers" cancer, ...
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Oncology & Cancer
Combination therapy for Burkitt's lymphoma dramatically improves cure rates in mice
Burkitt's lymphoma is a rare and aggressive blood cancer characterized by a translocation of the MYC gene. It occurs most often in children and young adults. In recent years, CAR-T cell therapy—often referred to as a "living ...
8 hours ago
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Tumor bacteria linked to immunotherapy resistance in head and neck cancer
Cleveland Clinic researchers have discovered that bacteria inside cancerous tumors may be key to understanding why immunotherapy works for some patients but not others.
19 hours ago
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Short, intensive workouts can help fight bowel cancer
As many of us embark on an exercise or gym routine for the new year, research reveals that just 10 minutes of intense exercise could help fight cancer.
15 hours ago
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Breast cancer drug boosts leukemia treatment: Unexpected duo shows promise in overcoming resistance
A research team at Oregon Health & Science University has discovered a promising new drug combination that may help people with acute myeloid leukemia overcome resistance to one of the most common frontline therapies.
Dec 29, 2025
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Machine learning identifies statin and phenothiazine combo for neuroblastoma treatment
Using machine learning and a large volume of data on genes and existing drugs, researchers at Lund University in Sweden have identified a combination of statins and phenothiazines that is particularly promising in the treatment ...
Dec 29, 2025
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Blocking a key gene regulator may restore immune response in cancer therapy
Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target tumors. Despite their initial clinical success, many patients eventually experience diminished therapeutic ...
Dec 29, 2025
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Researchers turn cancer resistance mutations into targets for new immunotherapies
One of the most challenging moments in cancer treatment comes when a therapy stops working. In many metastatic cancers, drugs that are initially effective lose their potency over time, as malignant cells acquire mutations ...
Dec 29, 2025
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How testosterone went from prostate cancer villain to potential ally
For more than 80 years, men have been told that testosterone helps prostate cancer grow. But a very different picture has emerged over the past two decades.
Dec 29, 2025
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Study finds a better way to screen for breast cancer
A pioneering study has found that an individualized approach to breast cancer screening that assesses patients' risk, rather than annual mammograms, can lower the chance of more advanced cancers, while still safely match ...
Dec 26, 2025
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How stomach cancer learns to grow on its own
Gastric (stomach) cancer remains one of the most common and deadly cancers in East Asia, including Korea. Yet despite its high prevalence, it has received far less molecular attention than colorectal cancer, which is more ...
Dec 25, 2025
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Scientists develop targeted therapy for T-cell lymphomas and leukemias
Researchers at the Johns Hopkins Kimmel Cancer Center's Ludwig Center developed a new treatment that selectively targets TRBC2-positive T-cell cancers, expanding a precision approach they established in 2024 for TRBC1-positive ...
Dec 25, 2025
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Rb1 identified as predictive biomarker for new therapeutic strategy in some breast cancers
A new study published in Science Translational Medicine by researchers at The University of Texas MD Anderson Cancer Center details a therapeutic vulnerability in patients with an aggressive subtype of triple-negative breast ...
Dec 24, 2025
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Novel AI tool offers prognosis for patients with head and neck cancer
A team led by investigators at Mass General Brigham and Dana-Farber Cancer Institute has developed and validated an artificial intelligence (AI)–based noninvasive tool that can predict the likelihood that a patient's oropharyngeal ...
Dec 24, 2025
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Stiffer colon could signal risk of early-onset colorectal cancer
Increased stiffness of the colon, spurred by chronic inflammation, may encourage the development and progression of early-onset colorectal cancer (CRC), a study co-led by UT Southwestern Medical Center researchers suggests. ...
Dec 23, 2025
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Night shifts aren't just tiring, they can be deadly: Disrupted sleep cycles linked to aggressive breast cancer
Working the night shift, frequently flying across time zones or keeping an irregular sleep schedule does more than just leave us exhausted; it can fuel the risk of aggressive breast cancer. Exactly how and why this happens ...
Dec 23, 2025
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Inflammation fuels one of the most aggressive forms of lung cancer
Small cell lung cancer (SCLC) is one of the most aggressive forms of lung cancer, with a five-year survival rate of only 5%. Despite this poor prognosis, SCLC is initially highly responsive to chemotherapy. However, patients ...
Dec 23, 2025
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Protein MCL1 links cancer cell survival and energy metabolism
A study by the Mildred Scheel Early Career Center group led by Dr. Mohamed Elgendy at the TUD Faculty of Medicine provides fundamental insights into cancer biology. Published in Nature Communications, the study shows for ...
Dec 23, 2025
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Locally brewed alcohol and chewing tobacco drive 62% of mouth cancer cases in India, study suggests
Even a low daily intake of alcohol—just 9 g or around one standard drink—is linked to a 50% heightened risk of mouth (buccal mucosa) cancer in India, with the greatest risk associated with locally brewed alcohol, finds ...
Dec 23, 2025
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TIGIT protein inhibition could help immune system target cancer cells
Researchers at the University of Sharjah are exploring a promising approach that could enhance the immune system's ability to fight cancer, potentially paving the way for new treatments.
Dec 23, 2025
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Any reduction in alcohol consumption helps reduce cancer risk: Support for 'Dry January'
Most people know that smoking causes cancer and that there's no "safe" number of cigarettes that are OK to smoke.
Dec 23, 2025
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FDA approves first subcutaneous drug for EGFR-mutated non-small cell lung cancer
The U.S. Food and Drug Administration has approved Rybrevant Faspro (amivantamab and hyaluronidase-lpuj) as the first and only subcutaneously administered therapy for patients with epidermal growth factor receptor (EGFR)-mutated ...
Dec 23, 2025
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How brain tumor cells influence neurons and vice versa
Gliomas are cancers that originate directly in the brain, instead of spreading to the brain from other parts of the body. These cancers cannot be cured with conventional cancer treatments, as they spread into healthy brain ...
High-fat diets make liver cells more susceptible to cancer-causing mutations, study shows
One of the biggest risk factors for developing liver cancer is a high-fat diet. A new study from MIT reveals how a fatty diet rewires liver cells and makes them more prone to becoming cancerous.
Dec 22, 2025
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Open-source software sheds light on cancer's hidden genetic networks
University of Navarra (Spain) researchers have developed RNACOREX, a new open-source software capable of identifying gene regulation networks with applications in cancer survival analysis.
Dec 22, 2025
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