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Oncology news
Hidden reservoir may drive brain cancer relapse in 65% of patients
All types of brain cancers collectively have a five-year survival rate of just 33%, according to the National Cancer Institute's Surveillance, Epidemiology, and End Results Program. For a type of brain cancer called glioblastoma, ...
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Testosterone suppresses brain tumor growth in males, study suggests
In a new study, scientists at Cleveland Clinic discovered that hormones associated with male development may play a key role in limiting the growth of brain tumors in men. The research team found that the loss of androgen ...
2 hours ago
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Blood test reveals nine tumor cell 'neighborhoods' tied to immunotherapy outcomes
A simple blood test can reveal the geographic relationships among healthy cells surrounding a cancerous tumor, researchers at Stanford Medicine and the Mayo Clinic have found. The test is the first noninvasive way to study ...
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Vitamin C and cancer: Was Nobel laureate Linus Pauling on to something?
Linus Pauling was one of the most brilliant scientists of the 20th century. He won two Nobel prizes and transformed our understanding of chemical bonds and the structure of proteins. Late in his career, though, he became ...
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Scientists find blood-based biomarkers for inflammatory breast cancer
Researchers at The University of Texas MD Anderson Cancer Center and The University of Texas at Austin have identified specific blood-based genomic biomarkers that distinguish inflammatory breast cancer from other subtypes, ...
2 hours ago
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Researchers find biomarker of chemotherapy resistance in relapsed lung cancer
Researchers from The University of Texas MD Anderson Cancer Center have discovered that some cancer cells express the YAP1 protein only after treatment with chemotherapy, allowing them to survive by becoming more invasive ...
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AI pathology framework can enable a deeper understanding of cancer
The digital transformation of pathology is opening up new possibilities for cancer diagnosis. Today's artificial intelligence (AI) techniques now go far beyond mere automation: they make it possible to extract previously ...
23 hours ago
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This hand-held cancer probe feels what surgeons may miss and changes how tumors are found in real time
Breast cancer impacts over two million women around the world each year. Following radiotherapy or chemotherapy, breast-conserving surgery is the first line of intervention for early-stage breast cancer. This surgery aims ...
May 5, 2026
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Study surveys dysfunctional gene splicing in metastatic kidney disease
Researchers at City of Hope and TGen (part of City of Hope) have identified a significant correlation between a tumor's "splicing burden" and its clinical response to treatment for metastatic renal cell carcinoma (mRCC). ...
May 5, 2026
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Complete remission of aggressive pituitary tumor achieved through immunotherapy
Researchers at the University of Cincinnati Gardner Neuroscience Institute's Brain Tumor Center have been confirmed as the first in the world to achieve complete remission of a rare pituitary cancer using a novel immunotherapy ...
May 4, 2026
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One missing metabolic step can turn cancer's DNA-copying machinery into a lethal weakness
Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern ...
May 4, 2026
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Enzyme shields triple-negative breast cancer cells from replication stress
Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps triple-negative breast cancer (TNBC) cells survive high levels of DNA replication stress. Because many breast ...
May 4, 2026
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FDA grants expanded access to the pancreatic cancer drug daraxonrasib
The U.S. Food and Drug Administration (FDA) has granted expanded access for the use of an experimental pancreatic cancer drug, daraxonrasib. This means the drug will be available for early access to those who previously received ...
May 4, 2026
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ASBrS: Robotic nipple-sparing mastectomy safe, effective in early breast cancer
For patients with early-stage breast cancer, robotic nipple-sparing mastectomy (rNSM) is as safe and effective as open NSM, according to a study presented at the annual meeting of the American Society of Breast Surgeons, ...
May 4, 2026
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Some breast cancer survivors need closer heart disease monitoring
The racial makeup and socioeconomic status of early-stage breast cancer patients could offer clues about their risk for heart disease, the leading cause of death among breast cancer survivors. Results of a study led by a ...
May 4, 2026
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Mistletoe extract shows no effect in patients with advanced pancreatic cancer
New research shows that palliative patients with pancreatic cancer neither live longer nor experience improved quality of life when taking mistletoe extract in addition to standard cancer treatment, compared to placebo. The ...
May 4, 2026
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Proteins found in cancer extracellular vesicles could guide drug development
Cancer cells release tiny biological packages called extracellular vesicles (EVs) that help tumors grow and spread. A team led by Cedars-Sinai Health Sciences University investigators has now connected certain proteins carried ...
May 4, 2026
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Blocking a cellular inflammation process could result in effective therapy for pancreatic cancer
Scientists at The Wistar Institute and clinical researchers from ChristianaCare's Helen F. Graham Cancer Center & Research Institute have discovered a vulnerability in pancreatic cancer that could be targeted as a potential ...
May 3, 2026
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Low-dose drug cuts breast density up to 26% with fewer side effects
Low doses of the investigational medicinal product endoxifen reduce breast density to the same extent as the standard treatment tamoxifen, but without causing such troublesome side effects. This is shown by a new study from ...
May 3, 2026
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Liquid biopsy predicts response to breast cancer immunotherapy
Immunotherapy has become a standard of care in treating high-risk, early-stage breast cancers, yet it has had limited success in shrinking tumors. New biomarkers that can improve outcomes for patients are urgently needed. ...
May 3, 2026
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Blood test shows promise for detecting testicular cancer when standard markers miss
Mayo Clinic researchers have developed a blood-based method that may help detect germ cell tumors, the most common type of testicular cancer, including cases that do not show up on standard blood tests, according to a study ...
May 3, 2026
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Experimental KRAS G12D drug slows cancer growth, shrinks tumors in early test
A first-in-human clinical trial led by an international team of researchers and published in the New England Journal of Medicine found that setidegrasib, an investigational targeted therapy drug designed to eliminate a key ...
May 2, 2026
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Microchip nanoparticle test spots pancreatic cancer in blood, outperforming biopsy in early trial
Scientists at Oregon Health & Science University have developed a new technique using an electronic jolt and nanoparticles to reveal the telltale signal of an insidious form of cancer.
May 2, 2026
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New test promises to detect cancer earlier, from tiny particles in bodily fluids
Cancer claims more than 10 million lives every year globally. Research shows that detecting cancer early can greatly improve a patient's chance of survival. And yet we lack reliable, affordable tools for early detection.
May 2, 2026
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Medicaid restrictions could lead to over 1 million missed cancer screenings
A research letter from experts at the University of Chicago Medicine, published in JAMA Oncology, warns that upcoming funding cuts and changes to federal Medicaid eligibility rules could lead to dramatic reductions in cancer ...
May 2, 2026
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