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Oncology & Cancer news
Oncology & Cancer
Advancing genomic medicine: The evolution of personalized cancer treatment in Japan
The journey of cancer genomic medicine (CGM) began in the 1980s, with the discovery of various genomic and epigenomic alterations in cancer cells from various countries including Japan. This led to the development of molecular ...
2 hours ago
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Oncology & Cancer
Newly discovered mechanism of T-cell control can interfere with cancer immunotherapies
Activated T cells that carry a certain marker protein on their surface are controlled by natural killer (NK) cells, another cell type of the immune system. In this way, the body presumably curbs destructive immune reactions.
17 hours ago
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Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets
Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T–cell immunotherapy, where a patient's own immune cells are re-engineered to attack cancer ...
17 hours ago
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Scientists discover new immunosuppressive mechanism in brain cancer
The Wistar Institute assistant professor Filippo Veglia, Ph.D., and team, have discovered a key mechanism of how glioblastoma—a serious and often fatal brain cancer—suppresses the immune system so that the tumor can grow ...
17 hours ago
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Lymphocytes recruit the immune system to fight most aggressive breast cancer, study confirms
Researchers at the UAB and the Hospital del Mar Research Institute have confirmed that patients with the presence of NK lymphocytes around tumors have a better response to treatment. This confirms the feasibility of using ...
20 hours ago
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Combined therapy makes headway for liver cancer
A drug that targets a protein known as phosphatidylserine boosted the response rate for hepatocellular carcinoma (HCC) patients receiving immunotherapy without compromising their safety, according to results of a phase two ...
22 hours ago
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New approach for developing cancer vaccines could make immunotherapies more effective in acute myeloid leukemia
Acute myeloid leukemia (AML) is a type of blood cancer that forms in the soft marrow of the bones, typically attacking cells that would otherwise form the key component of the body's immunodefense system, white blood cells.
15 hours ago
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Drug targeting RNA modifications shows promise for treating neuroblastoma
Neuroblastoma is a common pediatric cancer that originates in developing nerve cells outside the brain. While increasingly intensive treatments have improved the survival of patients with high-risk neuroblastoma, currently ...
16 hours ago
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How cancer cells harness energy to drive disease progression
Researchers have revealed crucial insights into how the Warburg effect causes the dedifferentiation of cancer cells through epigenetic reprogramming. This discovery potentially opens up new avenues for cancer treatments that ...
17 hours ago
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The key role of Galectin-3 in brain tumor development
A research group at the Department of Biochemistry and Molecular Biology of the University of Seville has made a significant advance by discovering the crucial role of the protein Galectin-3 in the progression of various ...
17 hours ago
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Study shows extending interval between colonoscopies feasible after negative result
For individuals without a family history of colorectal cancer (CRC), increasing the interval between colonoscopies for those with a first colonoscopy with negative findings seems safe and can avoid unnecessary colonoscopies, ...
17 hours ago
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Gene expression and bioinformatics tools to optimize cancer therapy
In the field of biomedical research and genomics, the advancement of bioinformatics technologies and tools is opening new frontiers in the understanding of diseases and their diagnosis and treatment. In particular, differential ...
18 hours ago
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Scientists track 'doubling' in origin of cancer cells
Working with human breast and lung cells, Johns Hopkins Medicine scientists say they have charted a molecular pathway that can lure cells down a hazardous path of duplicating their genome too many times, a hallmark of cancer ...
May 2, 2024
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Researchers discover how immune B cells hunt down cancer around the body
Scientists have discovered the key features of immune B cells that make them successful at targeting tumors—including when cancer has spread to a different part of the body.
May 2, 2024
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Unknown risk factor linked to high rates of kidney cancer, DNA study finds
Researchers analyzing the DNA of people with kidney cancer worldwide have found evidence of an unknown trigger that could explain the longstanding mystery of why some countries have a higher incidence of the disease.
May 2, 2024
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Gene signatures from tissue-resident T cells as a predictive tool for melanoma patients
An extensive analytical study conducted at the Terasaki Institute for Biomedical Innovation (TIBI) has revealed an association between favorable survival outcomes for melanoma patients and the presence of higher populations ...
May 2, 2024
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Testing for residual cancer cells before blood cell transplant therapy is important and practical, new study finds
Patients in remission after battling a high-risk blood cancer are likely to have better outcomes if no trace of the cancer is detectable before the patients receive donor blood cells.
May 2, 2024
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Turning a tumor's 'shield' into a weapon against itself
Tumor cells are "cunning," according to Peter Yingxiao Wang. They have a nefarious way of evading the human immune responses that fight back against these cancerous invaders. Tumor cells express programmed death-ligand 1 ...
May 2, 2024
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Molecular testing: Pioneering precision medicine for colorectal cancer
A new perspective paper explores the current state and future directions of precision medicine in colorectal cancer (CRC). It outlines advancements in molecular testing and their implications for targeted and immunological ...
May 2, 2024
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Brain cancer in children is notoriously hard to treat—a new mRNA cancer vaccine triggers an attack from within
Brain cancers remain among the most challenging tumors to treat. They often don't respond to traditional treatments because many chemotherapies are unable to penetrate the protective barrier around the brain. Other treatments ...
May 2, 2024
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