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Oncology news
Breast tumors use sugar coating to evade immunity, opening potential immunotherapy path
Immunotherapies such as so-called checkpoint inhibitors activate the body's own immune system to fight cancer cells and have revolutionized the treatment of many types of tumor. In breast cancer, however, these therapies ...
18 hours ago
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Years after polyp removal, gut microbiome changes may still shape colorectal cancer risk
More than a decade after removal of an adenoma—a precancerous mass—from the colon, alterations to the gut microbiome and metabolites remain and may drive heightened risk of colorectal cancer (CRC), according to a study led ...
22 hours ago
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Lung cancer cells can revert identity to a branching state, fueling resistance and aggressive growth
Oncologists have discovered that lung cancer cells can change their identity to resist treatment. Research published in Molecular Oncology reveals how lung cancer cells can become more aggressive and harder to treat by reactivating ...
20 hours ago
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Naturally occurring molecule may help outsmart melanoma
Melanoma is one of the deadliest forms of skin cancer, due in large part to its ability to rapidly develop resistance to treatment. Now, researchers at the University of California San Diego have identified a naturally occurring ...
23 hours ago
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Simple blood test could lead to personalized lung cancer treatment
A single blood test could help doctors predict how lung cancer patients will respond to treatment before therapy begins, researchers have found. University of Queensland-led research focused on non-small cell lung cancer ...
21 hours ago
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Worse cancer mortality seen in association with exposure to coal operations
Occupational exposure and residential exposure to coal operations are associated with worse cancer mortality, according to a review published in Public Health.
13 hours ago
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Study: AI may help identify cancer survivors at risk for emergency visits, worsening symptoms
Artificial intelligence models using electronic health records and patient-reported outcomes may help identify cancer survivors at increased risk for emergency department visits, hospitalizations and worsening symptoms after ...
14 hours ago
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Weight-loss program helps women battling breast cancer
Women battling breast cancer can benefit from a phone-based weight loss program, according to a new study. The Breast Cancer Weight Loss (BWEL) program helped women drop excess pounds, improve their physical function and ...
15 hours ago
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Patients show strong response to at-home cancer test
A new analysis of clinical trial data led by Anisha P. Ganguly, MD, MPH, a general internist at UNC Health and member of UNC Lineberger Comprehensive Cancer Center, has proven that mailed fecal immunochemical tests can drastically ...
17 hours ago
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CASK protein drives lung cancer growth by blocking a key tumor-suppressor gene
In a study published in the Journal of Biomedical Science, researchers from National Taiwan University found that CASK helps promote the growth of non-small cell lung cancer (NSCLC) by regulating the EGFR–p21 signaling pathway. ...
18 hours ago
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2010 to 2021 saw increase in incidence of Stage IV breast cancer
From 2010 to 2021, there was a significant increase in the incidence of stage IV breast cancer, according to a study published online May 12 in JAMA Network Open.
20 hours ago
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KRAS degradation induces rapid lung cancer regression in preclinical mouse models
KRAS is one of the oncogenes most frequently altered in cancer, mutating in approximately one-third of lung adenocarcinomas. For decades, it was considered undruggable, until the recent approval of the first inhibitors against ...
23 hours ago
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Updated colorectal cancer guidelines endorse new stool tests, recommend limited use of blood tests
With colorectal cancer a growing concern among younger people, the American Cancer Society has endorsed two new types of stool tests to encourage people to get screened, while also recommending a limited role for new blood ...
May 27, 2026
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Vitamin D analog shuts down pancreatic cancer's shield in a clinical trial
A small clinical trial led by Dana-Farber Cancer Institute researchers has put a Salk Institute idea to the test in patients: that activating the vitamin D receptor can help reshape the protective environment surrounding ...
May 26, 2026
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CAR T moves beyond cancer, targeting autoimmune disease with immune system reset
At age 49, Jan Janisch-Hanzlik's multiple sclerosis was destroying her freedom to live the life she wanted. She gave up her active nursing job for a desk role. Frequent falls made her afraid to carry her grandchildren. She ...
May 26, 2026
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AI uncovers why squeezed tumors grow slower under physical pressure
Researchers have solved a long-standing mystery about why physical forces slow cancer growth—and the answer could reshape how the disease is treated. A multidisciplinary team from University of Galway, CÚRAM, the Taighde ...
May 26, 2026
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Immune memory cells in ovarian cancer produce tumor-targeting antibodies, opening a vaccine path
While we tend to quickly forget having been ill or having received a vaccine, the immune system remembers remarkably well. It has memory B cells—"trained" immune cells that circulate throughout the body in search of harmful ...
May 26, 2026
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Blocking two cancer pathways may curb medulloblastoma relapse, preclinical study suggests
For most children diagnosed with medulloblastoma, the most common malignant pediatric brain tumor, survival rates are encouraging. But for a subset, remission is not the end of the story. Roughly 30% of patients will see ...
May 26, 2026
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Blood test detects early signs of breast cancer recurrence
Researchers at Lund University have developed a blood test capable of detecting signs of breast cancer recurrence long before recurrence becomes visible on imaging or causes symptoms. It has previously been shown that this ...
May 26, 2026
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Rare 'burrowing' oral cancer shows distinct genetic profile for early diagnosis
Cancer diagnosis can be challenging, and delayed diagnosis can allow cancer to progress, complicating treatment. Oral squamous cell carcinoma (OSCC), the most common type of oral cancer, can sometimes mimic benign conditions, ...
May 26, 2026
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AI model links tumor mutations to treatment response
Researchers at University of California San Diego have developed a new artificial intelligence (AI) model that can translate a tumor's complex genetic profile into predictions about how that cancer may respond to treatment. ...
May 26, 2026
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Residual risks of liver cancer persist after hepatitis C cure, finds study
National Taiwan University Hospital (NTUH), in collaboration with multiple medical centers across Taiwan, has found that patients with hepatitis C remain at a significantly elevated risk of hepatocellular carcinoma (HCC) ...
May 26, 2026
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Does ceramide lipid metabolism affect response to prostate cancer drugs?
Ceramides—lipid molecules in cells that affect many physiological functions including cell differentiation, migration, and death—and their metabolites have been implicated in the development of cancer and other conditions. ...
May 26, 2026
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Researchers shape guidance for cancer screening
University of Warwick researchers have played a central role in developing new position statements from the UK National Screening Committee (UK NSC), setting out how emerging cancer screening technologies should be evaluated ...
May 26, 2026
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Chronic leukemia treatment may affect immunity long-term
Treatment with so-called BTK inhibitors has improved the prognosis for people with chronic lymphocytic leukemia (CLL). At the same time, these drugs affect the immune system and may cause side effects over time, according ...
May 26, 2026
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