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Oncology news

Ketone supplementation improves immunotherapy outcomes in mice, with human clinical trial underway

A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 in the journal Cell, ...

Wnt signaling drives stomach cancer spread by reshaping surrounding tissue, finds study

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs. Their study ...

Overcoming ovarian cancer's resistance to immunotherapy

Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors. Different forms ...

Light-sensing genes may connect three childhood tumor types

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St. Jude Children's Research ...

Study maps US diabetes–cancer hotspots

A new University of Kentucky study has mapped areas across the U.S. where high rates of diabetes and deaths from diabetes-related cancers overlap. The UK Markey Cancer Center and Barnstable Brown Diabetes Center research ...

GI cancers to double by 2050, experts warn

Gastrointestinal cancer cases are expected to double worldwide by 2050, according to a multi-institutional study co-led by Cedars-Sinai. The projections, based on 2022 data and published in the journal Cancer, conclude that ...

New AI tool predicts best pancreatic cancer treatment

A new tool co-developed by investigators from Cedars-Sinai Health Sciences University can predict which of two available chemotherapy options for pancreatic cancer would be more effective for an individual patient.

Open source cancer database created for easier disease study

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data—including ...

Molecular imaging may reduce need for melanoma biopsies

Douglas Grossman, MD, Ph.D., co-leader of the Melanoma Center at Huntsman Cancer Institute at the University of Utah (the U) and professor of dermatology at the U, has helped develop a noninvasive technology that aims to ...

Histotripsy can safely target the pancreas in laboratory study

Pancreatic cancer continues to be a devastating disease, with an overall 5-year survival rate of around 13%. Accounting for about 3% of all cancers, it is the third leading cause of cancer death in the United States. Difficulties ...

Microplastics discovered in prostate tumors

Small fragments of plastic were found in 9 out of 10 patients with prostate cancer, and in higher levels inside tumors than in nearby noncancerous tissue, a new study finds. The small, single-center study was led by researchers ...

Do you need to worry about thyroid nodules?

Your thyroid is a small, butterfly-shaped gland in the front of your neck. Its main job is to produce thyroid hormones, which help regulate your body's metabolism and control your heart rate, body temperature, growth and ...

Engineered CAR-NK cells appear more 'attack-ready'

Researchers at the Ribeirao Preto Blood Center and the Center for Cell-Based Therapy (CTC) conducted a study using the NK-92 cell line to test new models of chimeric antigen receptors (CARs) with specific costimulatory domains, ...