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Oncology news
CAR T cells with boosted BACH2 protein can fight cancer more effectively
UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving their therapeutic effectiveness. ...
56 minutes ago
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Discovery illuminates how inflammatory bowel disease promotes colorectal cancer
A chain of immune reactions in the gut—driven by a key signaling protein and a surge of white blood cells from the bone marrow—may help explain why people with inflammatory bowel disease (IBD) have a higher risk of colorectal ...
19 hours ago
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Breast cancer study reveals synergistic effect of CDK2 and CDK4/6 combination therapy
A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously ...
19 hours ago
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Experimental CAR T therapy targets tumor's immune shield, not cancer cells directly
Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the ...
21 hours ago
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AI tool predicts cancer metastasis risk using gene expression signatures
Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing patient care.
21 hours ago
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How pancreatic tumors use the MYC protein to evade immune detection
An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers. The scientists identified a potential central mechanism by which cancer cells protect themselves ...
23 hours ago
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Carbon-ion therapy offers nonsurgical option for early breast cancer treatment
For many women with early breast cancer, surgery is effective but life-altering. New five-year data from the National Institutes for Quantum Science and Technology (QST) suggest that a precisely targeted, high-energy particle ...
18 hours ago
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Q&A: Researcher discusses new tool to predict how cancer evolves
Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment. In a new study, scientists ...
18 hours ago
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Progression-free survival prolonged with sacituzumab govitecan plus pembrolizumab in triple-negative breast cancer
For patients with previously untreated, programmed death ligand 1 (PD-L1)-positive, locally advanced unresectable or metastatic triple-negative breast cancer (TNBC), sacituzumab govitecan plus pembrolizumab yields significantly ...
12 hours ago
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Q&A: At-home HPV tests may usher in a new era for cervical cancer screening
Regular cervical cancer screening using HPV testing and/or Pap tests can prevent up to 90% or more of cervical cancers by detecting and treating precancerous lesions early, making it one of the most preventable cancers. Yet, ...
18 hours ago
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Cancer vaccines promise personalized, combination treatment approaches, says research
A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, ...
19 hours ago
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Treating cancer with medication before surgery continues to increase, report shows
The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, ...
21 hours ago
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New approach offers hope for people with rare eye cancer
Researchers at Queen Mary's Barts Cancer Institute have found a more active approach to monitoring and treating people with a rare eye cancer (known as uveal melanoma) that has spread to the liver could help some patients ...
23 hours ago
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Ending dementia stigma could change its trajectory: Cancer's history shows why
At a recent party, another guest, a nurse, asked what I do for a living. I explained that as a health policy researcher, my work focuses on helping health-care systems coordinate care for dementia as effectively as for major ...
23 hours ago
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Chemotherapy rewires gut bacteria to curb metastasis, research reveals
Chemotherapy commonly damages the intestinal lining, a well-known side effect. But this injury does not remain confined to the gut. It reshapes nutrient availability for intestinal bacteria, forcing the microbiota to adapt.
Jan 22, 2026
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Researchers link obesity, estrogen use, and increased blood-clotting risk
A research team led by Dr. Rinku Majumder from LSU Health New Orleans has published a groundbreaking study in the Journal of Clinical Investigation showing how obesity and estrogen-based medications (including hormonal therapies ...
Jan 22, 2026
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How lung cancer's return pattern predicts survival after first treatment fails
When lung cancer treatment stops working, what happens next? New research reveals the answer may depend on how the cancer grows.
Jan 22, 2026
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Imaging technique can reduce benign breast biopsies by 25%
In breast cancer, a biopsy is the only diagnostic procedure that can determine if a suspicious lump or area is cancerous. However, in the U.S., between 75% and 80% of breast biopsies are benign.
Jan 22, 2026
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Drinking less could prevent cancer deaths, study suggests
Reducing annual alcohol consumption in Australia by one liter a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.
Jan 22, 2026
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Researcher identifies biomarkers that could improve early detection of pancreatic cancer
A researcher at the IU Indianapolis Fairbanks School of Public Health has identified a set of novel biomarkers that could significantly improve early detection of pancreatic cancer, a disease with a five-year survival rate ...
Jan 22, 2026
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Small number of 'highly plastic' cancer cells drive disease progression and treatment resistance
A small number of cancer cells with the ability to change their identities and behaviors appear to be a key driver of cancer progression and its ability to evolve resistance to treatment.
Jan 21, 2026
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Super-enhancers in cancer cells trigger DNA breaks and error-prone repair cycles
A new study shows that cancer damages its own DNA by pushing key genes to work too hard. Researchers found that the most powerful genetic "on switches" in cancer cells, called super-enhancers, drive unusually intense gene ...
Jan 21, 2026
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Scientists uncover hidden cells fueling brain cancer—and a drug that could stop them
A team of Canadian scientists has uncovered a new way to slow the growth of glioblastoma, the most aggressive and currently incurable form of brain cancer—and identified an existing medication that could treat it.
Jan 21, 2026
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Virtual histography: From tissue section to 3D image
Histology is one of the foundations of modern diagnostics. When physicians want to determine whether tissue is pathologically altered, they rely on microscopic tissue analysis: They cut the tissue into ultrathin sections, ...
Jan 21, 2026
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Scientists reveal splicing-based mechanism driving therapy resistance in pediatric acute myeloid leukemia
Pediatric acute myeloid leukemia (AML) is one of the most common acute leukemias in children. While treatment outcomes have improved in recent years, approximately 30% of patients relapse following initial chemotherapy and ...
Jan 21, 2026
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