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Oncology news

Wnt signaling drives stomach cancer spread by reshaping surrounding tissue, finds study

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs. Their study ...

Ketone supplementation improves immunotherapy outcomes in mice, with human clinical trial underway

A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 in the journal Cell, ...

Overcoming ovarian cancer's resistance to immunotherapy

Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors. Different forms ...

Light-sensing genes may connect three childhood tumor types

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St. Jude Children's Research ...

Study maps US diabetes–cancer hotspots

A new University of Kentucky study has mapped areas across the U.S. where high rates of diabetes and deaths from diabetes-related cancers overlap. The UK Markey Cancer Center and Barnstable Brown Diabetes Center research ...

GI cancers to double by 2050, experts warn

Gastrointestinal cancer cases are expected to double worldwide by 2050, according to a multi-institutional study co-led by Cedars-Sinai. The projections, based on 2022 data and published in the journal Cancer, conclude that ...

New AI tool predicts best pancreatic cancer treatment

A new tool co-developed by investigators from Cedars-Sinai Health Sciences University can predict which of two available chemotherapy options for pancreatic cancer would be more effective for an individual patient.

Open source cancer database created for easier disease study

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data—including ...

How the environment may affect breast cancer risk

In the United States, breast cancer is the most common cancer diagnosed among women. In Texas, more than 22,000 women were expected to be diagnosed with breast cancer in 2025, according to the Texas Department of State Health ...

Discovery could improve immune checkpoint inhibitor safety

For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar brand names. However, ...

Newly discovered virus linked to colorectal cancer

Colorectal cancer is one of the most common types of cancer in the Western world and a leading cause of cancer-related deaths. Age, diet and lifestyle are known risk factors. However, in most cases we still lack a precise ...

Interoperable data systems can improve cancer care

Cancer centers today are facing growing pressure from stakeholders across the cancer care and research community to meet data-driven expectations. Yet many centers continue to rely on fragmented, siloed data systems that ...

Cancer stress protein helps tumors hide from immune system

A protein made by stressed cancer cells helps lung and pancreatic tumors evade the immune system, a new study shows. Led by researchers from NYU Langone Health, the work found that new drugs designed to block the action of ...