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Oncology news
Tiny molecules called tRNA halves may contribute to prostate cancer cell growth
Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new potential therapeutic target in tiny molecules called tRNA halves.
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A mechanical view on metastasis: Tumor cell viscosity found to guide key steps in cancer spread
Millions of people worldwide are diagnosed with cancer every year. In advanced tumor diseases, cancer cells detach from the original tumor and settle in other parts of the body to form metastases. On their way, they have ...
1 hour ago
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Regenerating lost lymph nodes with bioengineered tissues
The rising incidence of cancer worldwide has led to an increasing number of surgeries that involve the removal of lymph nodes. Although these procedures play a major role in cancer staging and preventing the spread of malignancies, ...
1 hour ago
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Colon cancer now top cancer killer for Americans under 50, study finds
Colon cancer is now the No. 1 cause of cancer deaths in Americans under 50. It claimed that spot seven years earlier than previously projected. Colon cancer deaths among people under 50 have risen roughly 1% each year since ...
2 hours ago
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Uncovering cancer's hidden oncRNA signatures: From discovery to liquid biopsy
After being described in 2018, researchers knew they had something interesting with T3p, a single small RNA found in breast cancer but absent from normal tissue. The molecule took the team on a six-year journey to systematically ...
3 hours ago
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CAR T cells with boosted BACH2 protein can fight cancer more effectively
UT Southwestern Medical Center researchers have discovered that increasing the levels of a protein called BACH2 makes engineered cancer-fighting immune cells behave more like stem cells, improving their therapeutic effectiveness. ...
4 hours ago
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Targeted radiation therapy can be safely combined with chemotherapy, study finds
A University of Kentucky Markey Cancer Center study shows that a targeted form of radiation therapy can be safely delivered alongside high-dose chemotherapy and systemic therapy without requiring patients to pause their cancer ...
2 hours ago
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Discovery illuminates how inflammatory bowel disease promotes colorectal cancer
A chain of immune reactions in the gut—driven by a key signaling protein and a surge of white blood cells from the bone marrow—may help explain why people with inflammatory bowel disease (IBD) have a higher risk of colorectal ...
22 hours ago
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Breast cancer study reveals synergistic effect of CDK2 and CDK4/6 combination therapy
A new preclinical study from researchers at The University of Texas MD Anderson Cancer Center, published in Nature Communications, identifies a powerful strategy to overcome drug resistance in breast cancer by simultaneously ...
23 hours ago
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Carbon-ion therapy offers nonsurgical option for early breast cancer treatment
For many women with early breast cancer, surgery is effective but life-altering. New five-year data from the National Institutes for Quantum Science and Technology (QST) suggest that a precisely targeted, high-energy particle ...
21 hours ago
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Q&A: Researcher discusses new tool to predict how cancer evolves
Researchers at Moffitt Cancer Center have developed a new way to predict how cancer cells evolve by gaining and losing whole chromosomes, changes that help tumors grow, adapt and resist treatment. In a new study, scientists ...
22 hours ago
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Progression-free survival prolonged with sacituzumab govitecan plus pembrolizumab in triple-negative breast cancer
For patients with previously untreated, programmed death ligand 1 (PD-L1)-positive, locally advanced unresectable or metastatic triple-negative breast cancer (TNBC), sacituzumab govitecan plus pembrolizumab yields significantly ...
16 hours ago
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Q&A: At-home HPV tests may usher in a new era for cervical cancer screening
Regular cervical cancer screening using HPV testing and/or Pap tests can prevent up to 90% or more of cervical cancers by detecting and treating precancerous lesions early, making it one of the most preventable cancers. Yet, ...
22 hours ago
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Cancer vaccines promise personalized, combination treatment approaches, says research
A new comprehensive review from researchers at the Icahn School of Medicine at Mount Sinai details how decades of cancer vaccine research are converging into a new era of more precise, personalized, and effective immunotherapies, ...
23 hours ago
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Experimental CAR T therapy targets tumor's immune shield, not cancer cells directly
Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the ...
Jan 22, 2026
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AI tool predicts cancer metastasis risk using gene expression signatures
Why do some tumors spread while others remain localized? The mechanisms governing the metastatic potential of tumor cells remain largely unknown—yet understanding this is crucial for optimizing patient care.
Jan 22, 2026
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How pancreatic tumors use the MYC protein to evade immune detection
An international research team has succeeded in deciphering a key mechanism that controls the growth of pancreatic cancers. The scientists identified a potential central mechanism by which cancer cells protect themselves ...
Jan 22, 2026
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Chemotherapy rewires gut bacteria to curb metastasis, research reveals
Chemotherapy commonly damages the intestinal lining, a well-known side effect. But this injury does not remain confined to the gut. It reshapes nutrient availability for intestinal bacteria, forcing the microbiota to adapt.
Jan 22, 2026
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Researchers link obesity, estrogen use, and increased blood-clotting risk
A research team led by Dr. Rinku Majumder from LSU Health New Orleans has published a groundbreaking study in the Journal of Clinical Investigation showing how obesity and estrogen-based medications (including hormonal therapies ...
Jan 22, 2026
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Treating cancer with medication before surgery continues to increase, report shows
The second annual report from the National Cancer Database (NCDB) of the American College of Surgeons (ACS) documents a substantial rise in medication treatments, such as chemotherapy, immunotherapy, and hormone therapy, ...
Jan 22, 2026
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New approach offers hope for people with rare eye cancer
Researchers at Queen Mary's Barts Cancer Institute have found a more active approach to monitoring and treating people with a rare eye cancer (known as uveal melanoma) that has spread to the liver could help some patients ...
Jan 22, 2026
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Ending dementia stigma could change its trajectory: Cancer's history shows why
At a recent party, another guest, a nurse, asked what I do for a living. I explained that as a health policy researcher, my work focuses on helping health-care systems coordinate care for dementia as effectively as for major ...
Jan 22, 2026
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How lung cancer's return pattern predicts survival after first treatment fails
When lung cancer treatment stops working, what happens next? New research reveals the answer may depend on how the cancer grows.
Jan 22, 2026
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Imaging technique can reduce benign breast biopsies by 25%
In breast cancer, a biopsy is the only diagnostic procedure that can determine if a suspicious lump or area is cancerous. However, in the U.S., between 75% and 80% of breast biopsies are benign.
Jan 22, 2026
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Drinking less could prevent cancer deaths, study suggests
Reducing annual alcohol consumption in Australia by one liter a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.
Jan 22, 2026
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