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Oncology news
Direct-to-proteasome strategy degrades two cancer proteins and may curb drug resistance
A preclinical study has developed a strategy that enables the forced elimination of proteins that help tumors survive chemotherapy. This finding opens a new avenue to tackle resistance to cancer treatments, one of the major ...
1 hour ago
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One overlooked detail in cancer genomes is rewriting which mutations really matter
It's a fundamental principle of science: Correlation does not equal causation. Every cancer cell has genetic mutations, but not all of those mutations necessarily drive the cancer.
3 hours ago
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New treatment approach targets a subset of common blood cancer that is more deadly in women than in men
In a finding that challenges decades of assumptions about blood cancer, an international research team has shown for the first time that a specific subtype of diffuse large B cell lymphoma (DLBCL), which is the most common ...
2 hours ago
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Common inflammatory genes link pancreatic cancer with obesity and diabetes
New research shows that the same genes are active in pancreatic cancer, obesity and diabetes, helping to explain why people with metabolic disease often face poorer cancer outcomes and pointing to future ways to predict recurrence ...
3 hours ago
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AI screening tool gives pathologists 'spatial super vision' to detect hidden cancer
QIMR Berghofer scientists have developed an AI screening tool that harnesses the power of cutting-edge spatial biology analysis to give pathologists "super vision" to detect hidden genetic markers of cancer in standard patient ...
5 hours ago
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Can AI forecast immune responses? New benchmark shows where predictions hold up and fail
Artificial intelligence is increasingly being used to help scientists accelerate drug discovery and search for new treatments. But for AI tools to work effectively, researchers need to know whether they can be validated and ...
6 hours ago
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Hidden reservoir may drive brain cancer relapse in 65% of patients
All types of brain cancers collectively have a five-year survival rate of just 33%, according to the National Cancer Institute's Surveillance, Epidemiology, and End Results Program. For a type of brain cancer called glioblastoma, ...
6 hours ago
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How changes to proteins can alter drug interactions for new precision therapies
Inside every human cell, proteins are constantly being tagged with small chemical modifications after they're produced. Known as post-translational modifications, or PTMs, these can change how a protein folds, where it travels ...
2 hours ago
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Testosterone suppresses brain tumor growth in males, study suggests
In a new study, scientists at Cleveland Clinic discovered that hormones associated with male development may play a key role in limiting the growth of brain tumors in men. The research team found that the loss of androgen ...
8 hours ago
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To combat the youth vaping epidemic, AI can help determine which cessation strategies work best
Nationwide, young people ages 18–24 are the heaviest users of e-cigarettes, with 38.4% of youth reporting habitual use. E-cigarettes are also very popular in Western New York, with significantly higher use than in New York ...
4 hours ago
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Blood test reveals nine tumor cell 'neighborhoods' tied to immunotherapy outcomes
A simple blood test can reveal the geographic relationships among healthy cells surrounding a cancerous tumor, researchers at Stanford Medicine and the Mayo Clinic have found. The test is the first noninvasive way to study ...
8 hours ago
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Physicians achieve 95% cure rate for sickle cell disease with bone marrow transplant
A reduced-intensity bone marrow transplant regimen developed by Johns Hopkins physicians provides durable engraftment with low rejection rates and also may preserve fertility, according to results of a new study conducted ...
4 hours ago
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Vitamin C and cancer: Was Nobel laureate Linus Pauling on to something?
Linus Pauling was one of the most brilliant scientists of the 20th century. He won two Nobel prizes and transformed our understanding of chemical bonds and the structure of proteins. Late in his career, though, he became ...
7 hours ago
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Scientists find blood-based biomarkers for inflammatory breast cancer
Researchers at The University of Texas MD Anderson Cancer Center and The University of Texas at Austin have identified specific blood-based genomic biomarkers that distinguish inflammatory breast cancer from other subtypes, ...
8 hours ago
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Researchers find biomarker of chemotherapy resistance in relapsed lung cancer
Researchers from The University of Texas MD Anderson Cancer Center have discovered that some cancer cells express the YAP1 protein only after treatment with chemotherapy, allowing them to survive by becoming more invasive ...
12 hours ago
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AI pathology framework can enable a deeper understanding of cancer
The digital transformation of pathology is opening up new possibilities for cancer diagnosis. Today's artificial intelligence (AI) techniques now go far beyond mere automation: they make it possible to extract previously ...
May 5, 2026
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This hand-held cancer probe feels what surgeons may miss and changes how tumors are found in real time
Breast cancer impacts over two million women around the world each year. Following radiotherapy or chemotherapy, breast-conserving surgery is the first line of intervention for early-stage breast cancer. This surgery aims ...
May 5, 2026
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Study surveys dysfunctional gene splicing in metastatic kidney disease
Researchers at City of Hope and TGen (part of City of Hope) have identified a significant correlation between a tumor's "splicing burden" and its clinical response to treatment for metastatic renal cell carcinoma (mRCC). ...
May 5, 2026
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Complete remission of aggressive pituitary tumor achieved through immunotherapy
Researchers at the University of Cincinnati Gardner Neuroscience Institute's Brain Tumor Center have been confirmed as the first in the world to achieve complete remission of a rare pituitary cancer using a novel immunotherapy ...
May 4, 2026
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One missing metabolic step can turn cancer's DNA-copying machinery into a lethal weakness
Loss of an enzyme necessary for a process called lipoylation disrupts the way cancer cells copy their DNA, increasing their vulnerability to a class of anticancer drugs known as PARP inhibitors, a study led by UT Southwestern ...
May 4, 2026
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Enzyme shields triple-negative breast cancer cells from replication stress
Researchers at The University of Texas MD Anderson Cancer Center have identified a key enzyme—RNase H2—that helps triple-negative breast cancer (TNBC) cells survive high levels of DNA replication stress. Because many breast ...
May 4, 2026
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FDA grants expanded access to the pancreatic cancer drug daraxonrasib
The U.S. Food and Drug Administration (FDA) has granted expanded access for the use of an experimental pancreatic cancer drug, daraxonrasib. This means the drug will be available for early access to those who previously received ...
May 4, 2026
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ASBrS: Robotic nipple-sparing mastectomy safe, effective in early breast cancer
For patients with early-stage breast cancer, robotic nipple-sparing mastectomy (rNSM) is as safe and effective as open NSM, according to a study presented at the annual meeting of the American Society of Breast Surgeons, ...
May 4, 2026
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Some breast cancer survivors need closer heart disease monitoring
The racial makeup and socioeconomic status of early-stage breast cancer patients could offer clues about their risk for heart disease, the leading cause of death among breast cancer survivors. Results of a study led by a ...
May 4, 2026
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