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Oncology news

Ketone supplementation improves immunotherapy outcomes in mice, with human clinical trial underway

A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 in the journal Cell, ...

Wnt signaling drives stomach cancer spread by reshaping surrounding tissue, finds study

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to distant organs. Their study ...

Overcoming ovarian cancer's resistance to immunotherapy

Cells in our immune system are best known for providing security against external invaders such as bacteria and viruses. These immune cells also guard against internal threats, including cancerous tumors. Different forms ...

Light-sensing genes may connect three childhood tumor types

Research uncovering the origin of pineoblastoma, a rare pediatric brain tumor, has also revealed a dependency across multiple brain tumor types that share a similar molecular program. Scientists at St. Jude Children's Research ...

Study maps US diabetes–cancer hotspots

A new University of Kentucky study has mapped areas across the U.S. where high rates of diabetes and deaths from diabetes-related cancers overlap. The UK Markey Cancer Center and Barnstable Brown Diabetes Center research ...

GI cancers to double by 2050, experts warn

Gastrointestinal cancer cases are expected to double worldwide by 2050, according to a multi-institutional study co-led by Cedars-Sinai. The projections, based on 2022 data and published in the journal Cancer, conclude that ...

New AI tool predicts best pancreatic cancer treatment

A new tool co-developed by investigators from Cedars-Sinai Health Sciences University can predict which of two available chemotherapy options for pancreatic cancer would be more effective for an individual patient.

Open source cancer database created for easier disease study

Researchers from the Johns Hopkins Kimmel Cancer Center and The Johns Hopkins University have created a novel database structure that allows investigators anywhere to more easily study multiple types of cancer data—including ...

Cancer cell study sheds light on cachexia's origins

New research from the University of Oklahoma, published today in Cancer Cell, describes for the first time a "triangle regulation theory" of cancer-induced cachexia and anorexia. Cachexia is a muscle-wasting and fat-loss ...

New characteristics of aggressive prostate cancer identified

For the first time ever, NTNU researchers have identified new characteristics of aggressive prostate cancer. The research lays a foundation for the possibility that aggressive prostate cancer can probably be detected through ...

Rallying more T-cells to immunotherapy's fight against cancer

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...

New research results in changes to NHS guidelines

Hundreds of people with advanced bladder cancer across the UK can now receive three rather than six chemotherapy cycles following research by Queen Mary University of London which has led to a change to NHS treatment guidelines. ...