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Oncology news

Study identifies a new class of drug targets for aggressive leukemia

Hyperactive signaling pathways of some aggressive blood cancer cells can be tamped down by a previously unrecognized protein complex, ensuring the cancer's survival. If one component of the complex is deleted or removed, ...

How pancreatic cancer prepares the tumor environment: A possible biomarker for the earliest stage of development

Even before a tumor in the pancreas becomes discernible, an activated cancer gene actively remodels its future environment and creates an inflammatory and immune-defensive microenvironment in which the carcinoma can grow. ...

New characteristics of aggressive prostate cancer identified

For the first time ever, NTNU researchers have identified new characteristics of aggressive prostate cancer. The research lays a foundation for the possibility that aggressive prostate cancer can probably be detected through ...

Pancreatic cancer: Warning signs to heed

Your pancreas has important jobs to do. A large gland behind the lower part of the stomach, it produces hormones that regulate blood sugar and enzymes that help digest food. What if it develops cancer?

Cancer cell study sheds light on cachexia's origins

New research from the University of Oklahoma, published today in Cancer Cell, describes for the first time a "triangle regulation theory" of cancer-induced cachexia and anorexia. Cachexia is a muscle-wasting and fat-loss ...

Rallying more T-cells to immunotherapy's fight against cancer

Immune Checkpoint Blockade (ICB) has revolutionized the treatment of cancers like melanoma, but up to 60% of patients don't respond to this immunotherapy for reasons not yet fully understood. Australian scientists have found ...

New research results in changes to NHS guidelines

Hundreds of people with advanced bladder cancer across the UK can now receive three rather than six chemotherapy cycles following research by Queen Mary University of London which has led to a change to NHS treatment guidelines. ...

Tiny worm offers clues to combat chemotherapy neurotoxicity

Chemotherapy remains one of the most powerful tools in the fight against cancer, yet it often comes with significant long-term side effects that can dramatically affect patients' quality of life. Among the most debilitating ...

Established cancer drug can reactivate immunotherapy

Genetically modified immune cells can offer precious additional time to patients with advanced multiple myeloma. However, these therapies lose their impact as the molecules on cancer cells that immune cells recognize gradually ...

Can certain foods prevent stomach cancer?

Can what you eat help you avoid getting stomach cancer? "Most cases of stomach cancer happen sporadically and are purely a matter of bad luck," says Sharon Shiraga, MD, an upper-gastrointestinal surgeon with Keck Medicine ...

Drinking less could prevent cancer deaths, study suggests

Reducing annual alcohol consumption in Australia by one liter a person could significantly lower deaths from several major cancers, particularly among older Australians, a new study led by La Trobe University has found.

New approach offers hope for people with rare eye cancer

Researchers at Queen Mary's Barts Cancer Institute have found a more active approach to monitoring and treating people with a rare eye cancer (known as uveal melanoma) that has spread to the liver could help some patients ...