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Oncology & Cancer news
Oncology & Cancer
Integrating anatomy and biology for a better pancreatic cancer prognosis
Pancreatic ductal adenocarcinoma (PDAC) is notoriously difficult to treat due to its aggressive nature and limited prognostic tools. While the traditional staging systems, such as the TNM classification, focus on anatomical ...
5 hours ago
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Oncology & Cancer
Tanning beds mutate skin cells far beyond the reach of ordinary sunlight, study shows
Tanning bed use is tied to almost a three-fold increase in melanoma risk, and for the first time, scientists have shown how these devices cause melanoma-linked DNA damage across nearly the entire skin surface, reports a new ...
19 hours ago
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Study shows IL-36 gamma 'armored' CAR T cells can eradicate solid tumors
A laboratory study out of Roswell Park Comprehensive Cancer Center outlines a new way to boost the effectiveness of chimeric antigen receptor (CAR) T-cell therapy in solid-tumor cancers, resulting in their eradication. Led ...
22 hours ago
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Mini-tumors combine synthetic and real cells to simulate immune responses
Normally, the immune system recognizes and eliminates abnormal cells. However, cancer cells can develop strategies to evade this control: they block defense mechanisms or send inhibitory signals. In this way, tumors can grow ...
21 hours ago
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New immunotherapy targets for glioblastoma identified by mapping cell interactions
Glioblastoma is the most common form of brain cancer in adults, and its consequences are usually quick and fatal. After receiving standard-of-care treatment (surgery followed by radiation and chemotherapy), fewer than half ...
22 hours ago
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Adding antibody treatment to chemo boosts outcomes for children with rare cancer
Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical ...
17 hours ago
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Menopausal hormone therapy may not pose breast cancer risk for women with BRCA mutations, analysis suggests
Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited mutations in the BRCA1 or BRCA2 genes, according to the results of a matched prospective analysis presented ...
Dec 12, 2025
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Acupuncture may help improve perceived breast cancer-related cognitive difficulties over usual care
Real and sham acupuncture were more effective at improving breast cancer survivors' perceived cognitive impairment compared with usual care, while real acupuncture was superior to sham acupuncture in improving objective cognitive ...
Dec 12, 2025
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Mobile health tool may improve quality of life for adolescent and young adult breast cancer survivors
A mobile health (mHealth) intervention for adolescent and young adult breast cancer survivors that offered tailored support by monitoring electronic patient-reported outcomes (ePROs) significantly improved quality of life ...
Dec 12, 2025
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Proton therapy shows survival benefit in Phase III trial for patients with head and neck cancers
A study published in The Lancet showed a significant survival benefit for patients with oropharyngeal cancers who were treated with proton therapy (IMPT) compared to those treated with traditional radiation therapy (IMRT).
Dec 11, 2025
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Scientists uncover key driver of treatment-resistant cancer: Genome-scrambling enzyme points to new treatments
University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer ...
Dec 11, 2025
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Blocking collagen signaling boosts drug delivery in pancreatic cancer
Pancreatic cancer is one of the deadliest malignancies, with survival rates remaining dismally low despite major advances in oncology. One of the key reasons lies in the disease's unique fibrotic microenvironment—a dense, ...
Dec 11, 2025
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Tricking tumors into marking themselves for destruction with focused ultrasound
USC biomedical engineers have found a way to make a solid tumor paint a target on its own back in order to train the body's immune system to find and destroy it.
Dec 11, 2025
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How CAR T-cell therapies target myeloma at the molecular level
In multiple myeloma, plasma cells proliferate uncontrollably in the bone marrow, disrupting the growth of healthy blood-forming cells. If the disease recurs after treatment or fails to respond, CAR T-cell therapy may be considered. ...
Dec 11, 2025
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Phase I trial finds breast cancer vaccine triggers an immune response and is safe
Cleveland Clinic researchers are presenting final Phase I data from their novel study of a vaccine aimed at preventing triple-negative breast cancer, the most aggressive and lethal form of the disease.
Dec 11, 2025
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CAR-T therapy yields long-term survival for patients with lymphoma
A study published in the Journal of Clinical Oncology confirms that one of the first Food and Drug Administration-approved CAR-T cell therapies offers long-term survival and potential cures for adult patients with relapsed ...
Dec 11, 2025
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Imaging study solves a long-standing gap in metastatic breast cancer research and care
A prospective, multicenter cancer clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) has validated an improved method for predicting treatment benefits in patients with hormone receptor-positive (HR+) metastatic ...
Dec 11, 2025
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Bladder cancer surgeons improve their performance when monitored and given feedback
Providing surgeons feedback and education on their performance significantly improved the quality of bladder cancer operations, finds a new clinical trial led by researchers at UCL, UCLH and the University of Edinburgh.
Dec 11, 2025
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Research strengthens evidence linking alcohol use to cancer
As Americans gear up for the holiday season, new research offers a timely reminder to reflect on the long-term health effects of raising a celebratory glass—or two. Alcohol is known to increase the risk of several cancers ...
Dec 11, 2025
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Octopus-inspired 3D micro-LEDs pave the way for selective pancreatic cancer therapy
Conventional pancreatic cancer treatments face a critical hurdle due to the dense tumor microenvironment (TME). This biological barrier surrounds the tumor, severely limiting the infiltration of chemotherapy agents and immune ...
Dec 11, 2025
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Breast MRI may be safely omitted from diagnostic workup in certain patients with early-stage, HR-negative breast cancer
Patients with stage 1 or 2, hormone receptor (HR)-negative breast cancer had similar five-year rates of locoregional recurrence whether or not they underwent preoperative breast magnetic resonance imaging (MRI) in addition ...
Dec 11, 2025
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Preoperative radiation may improve antitumor immune response in most common form of breast cancer
Preoperative radiation improved T-cell infiltration (TCI) in patients with hormone receptor (HR)-positive, HER2-negative breast cancer when administered in combination with pembrolizumab (Keytruda) and chemotherapy and led ...
Dec 11, 2025
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Sentinel lymph node biopsy may be safely omitted in some patients with early-stage breast cancer: Phase III trial
Skipping sentinel lymph node biopsy (SLNB) in patients with clinically node-negative, hormonal receptor (HR)-positive, HER2-negative early-stage breast cancer did not compromise regional control or survival after a median ...
Dec 11, 2025
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Daily scans during prostate cancer could guide changes to treatment, reduce the risk of side effects, study suggests
Daily scans taken during prostate cancer radiotherapy could be repurposed to guide changes to treatment, reducing the risk of side effects, a study suggests.
Dec 11, 2025
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Making cancer screening more accessible to underserved groups
New research from the University of Aberdeen and the Grampian Regional Equality Council (GREC) has outlined ways to make cancer screening services more accessible to people who may be underserved by the health care system. ...
Dec 11, 2025
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