Institut Curie researchers have identified a sex-specific molecular pathway connecting E-cadherin loss, estrogen receptor-α (ERα), and GRPR, contributing significantly to increased melanoma metastasis in women.
Researchers have discovered that the most aggressive melanomas, the deadliest form of skin cancer, overactivate two key processes in mitochondria, the components of cells that provide energy. Blocking these pathways with ...
Jun 23, 2025
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Increased activity in a specific biological pathway may explain why many patients with a deadly form of skin cancer do not respond to the latest cancer treatments, a new study shows.
Jun 10, 2025
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Tests in 1,225 patients with the most deadly form of skin cancer reveal for the first time a genetic trait among most of those who did not respond to the latest cancer treatments, known as immune checkpoint inhibitors. Metastatic ...
Jun 5, 2025
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Reducing the length of immunotherapy treatment for an advanced skin cancer did not significantly diminish disease control when compared to giving treatments over a longer period, according to research led by the Universities ...
Jun 4, 2025
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Researchers have been working toward using the gut microbiome as a clinical target for screening for colorectal cancer. This would ideally allow simple stool tests to be used for early detection of the disease in place of ...
Jun 3, 2025
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Skin cancer is the most common cancer in the U.S. More than 6 million adults are treated for it each year, says Dr. Michael Colgan, a Mayo Clinic Health System dermatologist in Eau Claire, Wisconsin.
May 30, 2025
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If you are staring at a dark spot under your fingernail, you may want to see a dermatologist. It could be a form of melanoma.
May 22, 2025
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PAX3 is a transcription factor (proteins involved in converting DNA into RNA) that drives melanoma progression by promoting cell growth, migration and survival, while inhibiting cellular terminal differentiation, which is ...
May 19, 2025
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Research from The University of Western Australia has advanced the development of cancer treatments that enable immune cells to fight tumors more effectively.
May 15, 2025
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