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Gastroenterology news

FDA-approved drug may reverse T-cell exclusion in fibrolamellar liver cancer

Immunotherapy—which activates the body's own immune system to kill cancer cells—has not worked well against a rare and fatal liver cancer, but a new study finds an existing FDA-approved drug may allow the immunotherapy ...

Why are more under-50s getting colorectal cancer? 'We don't know'

The death of US actor James Van Der Beek was just the latest reminder that colorectal cancer has been surging among people under 50 in recent years—and no one knows why.

Studies show 11 genetic variants affect gut microbiome

In two new studies on 28,000 individuals, researchers are able to show that genetic variants in 11 regions of the human genome have a clear influence on which bacteria are in the gut and what they do there. Only two genetic ...

NSMF protein identified as key regulator in colorectal cancer

A research team affiliated with UNIST has unveiled a novel approach to halt the progression of colorectal cancer by inducing irreversible cellular aging. Their findings demonstrate that suppressing a neural protein called ...

Cholesterol crystals may trigger some liver disease

Cholesterol crystals in the liver may stiffen the organ early in those with metabolic dysfunction-associated steatotic liver disease (MASLD)—well before scarring develops—according to new research from a team in the Perelman ...

Pancreatic cancer: Warning signs to heed

Your pancreas has important jobs to do. A large gland behind the lower part of the stomach, it produces hormones that regulate blood sugar and enzymes that help digest food. What if it develops cancer?

Scientists create 'smart underwear' to measure human flatulence

Scientists at the University of Maryland have created Smart Underwear, the first wearable device designed to measure human flatulence. By tracking hydrogen in flatus, the device helps scientists revisit long-standing assumptions ...

Researchers develop a new model to study colorectal cancer

Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients. ...

French scientists probe mRNA's potential to fight cancer

Inside a lab in the French city of Orleans, scientists are testing out the limits of molecules in our body called messenger RNA—best known for being used in COVID-19 vaccines—in the hopes of finding a breakthrough treatment ...

Five everyday habits that could be harming your pancreas

The pancreas is essential for staying alive and healthy. This small organ sits behind the stomach and has two main jobs. It produces digestive enzymes that break down food and hormones such as insulin and glucagon that control ...

Is stomach cancer on the rise in young adults?

Stomach cancer, also referred to as gastric cancer, was once thought of as a disease of older adults. However, it is increasingly affecting people under the age of 50, mirroring a similar shift that is observed with colorectal ...

Gut bacterium could be key to tackling obesity crisis

The internet, libraries and bookshops are full of plans and advice on how to lose weight, from fad diets to intense exercise routines. But there could be another route to keeping the pounds away, and that's with a gut bacterium ...

Scientists map the cells that drive Crohn's disease fistulas

Scientists at the University of Oxford, have identified how rare populations of abnormal cells drive the formation and persistence of fistulas—painful, tunnel-like tracts that develop in around 30% of people with Crohn's ...