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Gastroenterology news
Experimental mRNA therapy dramatically extends treatment window for acetaminophen overdose in preclinical models
When a patient arrives at the hospital with an acetaminophen overdose, it's often a race against the clock. The only FDA-approved antidote for overdose-related liver injury, N‑acetylcysteine, must be administered within hours ...
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Stomach bacterium hijacks healing signals to drive precancerous changes, study finds
Stomach cancer is one of the deadliest forms of cancer. Unlike many other types of cancer, however, one of its main causes is well known: chronic infection with the bacterium Helicobacter pylori. A team headed by Charité—Universitätsmedizin ...
5 minutes ago
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Gut microbiome can reveal risk of type 2 diabetes
Changes in the composition of gut bacteria could provide an early warning of type 2 diabetes (T2D), according to new research being presented at the annual meeting of the European Association for the Study of Diabetes (EASD) ...
21 hours ago
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Experimental gene-silencing therapy offers hope for hepatitis B cure
Chronic hepatitis B is a long-lasting condition caused by the hepatitis B virus (HBV) that affects about 240 million people worldwide. Most people infected show no symptoms for years, but when symptoms do appear, they can ...
How the treatment of interleukin-6-driven diseases can be refined
Interleukin-6 (IL-6) is a contradictory molecule in immunology. It helps the liver regenerate after injury and protects against infections, yet it also drives chronic inflammation in rheumatic diseases, inflammatory bowel ...
Sep 25, 2026
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Why some patients may develop severe intestinal inflammation after CAR-T therapy
Researchers at the Icahn School of Medicine at Mount Sinai have identified biological mechanisms that may contribute to CAR-T cell-associated enterocolitis, a serious inflammatory condition of the intestine that can occur ...
Sep 25, 2026
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Steatotic liver disease risk scores compared for predicting cirrhosis
For patients with steatotic liver disease (SLD), the steatosis-associated fibrosis estimator (SAFE) score demonstrated the greatest net benefit for predicting cirrhosis, according to a study published online Sept. 21 in JAMA ...
Sep 25, 2026
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Appendectomy for appendicitis associated with 58% lower colorectal cancer risk than antibiotics alone
Patients who underwent an appendectomy for acute appendicitis had a significantly lower subsequent risk of colorectal cancer than similar patients treated with antibiotics alone, according to new research.
Sep 25, 2026
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Metastatic colorectal cancer is more advanced in younger patients than in older ones, but they survive longer
Metastatic colorectal cancer (mCRC) continues to increase among patients 45 and younger. Their longer survival and different disease patterns compared with older patients may warrant closer scrutiny of gastrointestinal symptoms, ...
Sep 25, 2026
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High-fat diet activates cellular repair pathway that helps colon cancer spread
Most colon cancer deaths are caused by the spread of tumor cells beyond the colon, usually to the liver. In a new study, MIT biologists identified a cellular pathway necessary for colorectal cancer metastasis.
Sep 24, 2026
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Food molecules transformed by gut bacteria and liver can still influence gene activity
The human liver and gut bacteria can alter molecules in food to influence signaling pathways that can activate or deactivate an array of genes, according to a new study led by researchers at Penn State.
Sep 24, 2026
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Restoring enzyme involved in cellular cleanup could reduce inflammation and scarring from liver disease MASH
A team of investigators co-led by Cedars-Sinai Health Sciences University has identified an enzyme that helps prevent the most common form of liver disease from progressing toward liver failure. Results of the preclinical ...
Sep 24, 2026
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New polymer could enable gastrointestinal transit monitoring without ionizing radiation
Scientists have developed a new fluorine-based tracer that can be tracked using magnetic resonance imaging (MRI) to monitor how quickly food moves through the gastrointestinal tract. The new method has so far been successfully ...
Sep 24, 2026
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Climate change is expanding extreme heat's threat to human health
I was 12 when the worst heat waves hit our home in rural New South Wales, Australia. It was summer vacation, a few weeks after we'd celebrated Christmas. I sat at the kitchen table, next to the sheets draped as curtains over ...
Sep 24, 2026
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IBD not linked to risk of hypertensive disorders of pregnancy overall
Inflammatory bowel disease (IBD) is not associated with an increased risk of hypertensive disorders of pregnancy overall, but it is associated with an increased risk of preeclampsia, according to a study published in the ...
Sep 24, 2026
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AI tool finds biological signals in the gut microbiome that other methods miss, may flag early signs of disease
University of Missouri researchers are using artificial intelligence to uncover hidden clues among the trillions of bacteria living in the human gut, including changes that could one day help scientists detect diseases earlier. ...
Sep 24, 2026
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Probiotics linked to fewer deaths in premature babies
Probiotic supplementation in very preterm babies was linked to a lower risk of both severe intestinal disease and death. This is shown by a new study from the Karolinska Institutet, published in JAMA Network Open. The findings ...
Sep 23, 2026
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Fiber is both diet fad and fixture for good health—why there is no one‑size‑fits‑all way to increase intake
The numbers are clear: Americans aren't getting enough fiber.
Sep 23, 2026
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Researchers find dietary interventions may prevent inflammatory symptoms associated with Hirschsprung disease
A multi-institutional study led by researchers at Children's Hospital of Philadelphia (CHOP) discovered for the first time that dietary interventions might prevent inflammatory symptoms associated with Hirschsprung disease, ...
Sep 23, 2026
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'Invisible' inflammation in rare bowel disease may explain heightened colon cancer risk
New research from the Garvan Institute of Medical Research has revealed for the first time that two closely related bowel diseases, currently treated in the same way, are fundamentally different. The findings help explain ...
Sep 22, 2026
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Cirrhosis can recur after liver transplant
Cirrhosis can recur after liver transplantation, according to a study published online Sept. 3 in Portal Hypertension & Cirrhosis.
Sep 22, 2026
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Batteries that safely break down in the GI tract could improve ingestible devices
Using materials safe for human consumption, MIT researchers have created tiny batteries that could be used to power ingestible electronic devices. Such batteries could make the devices safer for patients and minimize the ...
Sep 21, 2026
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U.S. alcohol use falls for first time since the COVID-19 pandemic but remains above pre-pandemic levels
Alcohol use among U.S. adults has fallen for the first time since the COVID-19 pandemic began, though rates remain higher than pre-pandemic levels, according to a new Keck Medicine of USC study published in Annals of Internal ...
Sep 21, 2026
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Rainwater tanks may be harboring hidden health risks
Rainwater tanks are a popular way for Australians to save water, but new research has found they can also harbor potentially harmful bacteria and metals that could pose health concerns.
Sep 21, 2026
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B cells may help predict risk of colitis from immunotherapy
Researchers at The University of Texas MD Anderson Cancer Center have identified a previously unknown role for B cells, adaptive immune cells, in triggering and sustaining colitis as a side effect of immune checkpoint inhibitors, ...
Sep 18, 2026
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