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Gastroenterology news
GLP-1 agonist drugs show digestive side effects but may help fight infections
Originally developed to treat diabetes, a class of drugs known as glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are now stepping into the spotlight as weight loss drugs. A recent umbrella review draws attention to ...
21 hours ago
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New mouse model of virus-driven liver cancer may boost diagnosis and treatments
Liver cancer is one of the world's deadliest cancers, and most cases are linked to chronic viral hepatitis. Yet scientists have lacked an animal model that faithfully recapitulates how the disease unfolds in people, from ...
13 hours ago
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New therapeutic target identified for neuroendocrine tumors in the gastrointestinal tract
Neuroendocrine cells are unique in their ability to act both as nerve cells and hormone-making cells. They're scattered throughout the body, including the stomach, intestines, pancreas and lungs. Tumors that arise from these ...
15 hours ago
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High‑fat diets linked to rapid decline in protective gut immune cells
In a preclinical study from Mass General Brigham, researchers have found that even short-term exposure to high levels of dietary fat results in a quick and selective loss of critical gut immune cells called ILC3s, promoting ...
15 hours ago
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Novel treatment protocol targets the deadliest cases of C. difficile infection
A new study from the University of Minnesota Medical School has demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant Clostridioides ...
14 hours ago
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Scientists target key protein duo driving colon, liver cancer
Cedars-Sinai Health Sciences University investigators have identified a drug-like compound that prevents two proteins from working together to promote the growth of colorectal and liver cancer. Findings from the preclinical ...
13 hours ago
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Researchers create first working model of specialized gut cells
Cedars-Sinai Health Sciences University investigators have for the first time created human intestinal organoids that include functional Paneth cells, a specialized cell type that is found in the inner lining of the intestine. ...
19 hours ago
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Cellular pathways that drive precancerous lesions to form pancreatic tumors identified
Pancreatic ductal adenocarcinoma is the most common type of pancreatic cancer and has a low five-year survival rate. It begins with a reversible state called acinar-to-ductal metaplasia, where cells can heal after injury ...
Apr 3, 2026
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Overnight machine perfusion lets liver transplants safely shift to daytime, study shows
It is safe for patients to receive a donor liver that has been intentionally preserved overnight using machine perfusion to enable a daytime transplant. This is shown by a study performed at the University Medical Center ...
Apr 3, 2026
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Could one protein play both sides? How Stard7 shifts colon cancer in different models
Alain Chariot's team has just published a study in EMBO Molecular Medicine shedding light on the unexpected role of the Stard7 protein in the development of intestinal cancers. Long regarded as a simple lipid transporter, ...
Apr 2, 2026
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How pancreatic tumors thwart an iron-driven demise
Tumors driven by cancer-driving KRAS mutations are often susceptible to ferroptosis, a type of cell death that can be harnessed for cancer therapy. Given that more than 95% of pancreatic ductal adenocarcinomas (PDACs) harbor ...
Apr 2, 2026
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Occasional heavy drinking may triple the risk of liver damage, research suggests
People may assume that if they drink lightly during the week or month, heavy drinking on the occasional Friday or Saturday may not cause their liver harm. New research suggests otherwise, according to a Keck Medicine of USC ...
Apr 2, 2026
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Radiation therapy improves outcomes for 'supermassive' bile duct tumors
A new study from researchers at The University of Texas MD Anderson Cancer Center demonstrates that a specialized high-dose type of radiation delivery may significantly improve outcomes for patients with large bile duct tumors ...
Apr 2, 2026
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Cause or effect? Study answers question about gene linked with colorectal cancer
A new study has answered a question that has puzzled cancer researchers for decades: Does a genetic defect found in nearly all human colorectal cancers simply accompany the disease, or does it trigger its development? A team ...
Apr 1, 2026
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How stomach cells rebuild after injury: Study uncovers key players in tissue regeneration
Researchers at Baylor College of Medicine and collaborating institutions took a closer look at how the gastrointestinal tissue repairs itself. They reveal in the Proceedings of the National Academy of Sciences key players ...
Apr 1, 2026
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Small intestinal bacterial overgrowth linked to worsening symptoms in allergic diseases
Allergies are usually associated with the immune system, genetics, and environmental factors. Increasingly, however, another element is appearing in this puzzle: the gut microbiota. A review of studies published in the International ...
Apr 1, 2026
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Celiac disease may blunt high-fiber benefits when key gut microbes are missing
Many people with celiac disease are advised to eat more fiber to support digestion and manage symptoms, either through diet or prescribed fiber supplements. New research from McMaster University shows that the benefits of ...
Mar 31, 2026
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Dental care can help cirrhosis patients avoid liver cancer, hospitalization
A healthy mouth is key to protecting the well-being of people battling liver disease, a new study reports. Veterans with early-stage cirrhosis had fewer health problems and complications—including a lower risk of liver cancer—if ...
Mar 31, 2026
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Fatigue highly prevalent in pediatric inflammatory bowel disease
Fatigue is highly prevalent in pediatric inflammatory bowel disease (IBD), according to a study published in the January issue of Crohn's and Colitis 360.
Mar 30, 2026
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Constipation is common, but with simple changes, you can manage and even prevent it
Chances are you've experienced constipation at some point in your life. It's one of the most common gastrointestinal complaints, affecting people of all ages, genders, and backgrounds. Constipation is typically defined as ...
Mar 30, 2026
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Boosting good gut bacteria population through targeted interventions may slow cognitive decline
The origin of neurodegenerative diseases like Alzheimer's or dementia isn't limited to the brain. The state of your gut can quietly set off a cycle of chronic, system-wide inflammation that nudges the brain toward cognitive ...
A new view of intestinal regeneration: What fetal reversion could mean for IBD and cancer
Dynamic switching between revival stem cells and conventional intestinal stem cells enables efficient tissue repair without exhausting the stem cell pool, report researchers from Institute of Science Tokyo. Using organoid ...
Mar 27, 2026
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Molecular test for bile duct cancer nearly doubles detection rate
When patients develop a narrowing or blockage in the bile ducts—the tubes connecting the liver, gallbladder and intestines—physicians must determine whether the cause is cancer or a benign condition. The location of these ...
Mar 27, 2026
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IBS diets don't work for everyone: New research shows why—and it's not just about the food
If you've ever tried a diet to fix gut symptoms, you'll know it can be hit or miss. One person swears it changed their life. Another follows it carefully and feels no better.
Mar 27, 2026
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Vitamin D supplements may shift immune responses to gut bacteria in IBD
Vitamin D supplementation may help shape how the immune system responds to gut bacteria in people with inflammatory bowel disease (IBD), according to a Mayo Clinic-led study published in Cell Reports Medicine.
Mar 26, 2026
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