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Gastroenterology news

Protein discovery reveals potential treatment target for common fatty liver disease

The mechanisms that cause the world's most common chronic liver disease—metabolic dysfunction-associated steatotic liver disease (MASLD)—to develop and progress are still not fully understood.

Gut microbiome could help identify people at risk of dementia

In what is thought to be the first study of its kind, researchers from Cardiff University and Imperial College London examined both gut bacteria and chemicals. Their findings could support earlier diagnosis and help spot ...

Imaging-based modalities compared for identifying at-risk MASH

FibroScan-aspartate aminotransferase (FAST) demonstrated the highest sensitivity for ruling out at-risk metabolic dysfunction-associated steatohepatitis (MASH), according to a study published in the October issue of the American ...

Kombucha may support mood and gut health

Researchers from the University of Minnesota found that drinking kombucha was associated with reduced anxiety and depressive-like behaviors in mice.

Untangling the link between depression and gut disease

Depression and gastrointestinal disorders frequently occur together. UC Irvine experts wondered if knowing which tends to be diagnosed first could shed light on the well-established but not yet fully understood gut-brain ...

How a diet free from animal proteins challenges the liver

Although a plant-based diet is recommended, notably for its environmental benefits, the health consequences of such a diet—in which protein intake is exclusively plant-based—are not yet fully understood. Scientists at the ...

Aspirin rarely used for colorectal cancer prevention

People with Lynch syndrome have a significantly increased risk of developing colorectal cancer and other types of cancer due to a hereditary predisposition. The CAPP2 study had already shown in this high-risk group that acetylsalicylic ...

New global research highlights burden of unsafe food

If it isn't safe, it isn't food. That message sits at the heart of a major new global effort by the World Health Organization (WHO). University of Waterloo public health researcher Dr. Shannon Majowicz contributed research ...

Colon cancer cells may change identity to metastasize

Loss of GATA6—a transcription factor that controls which genes are turned on or off—can reprogram colorectal cancer cells into more primitive, adaptable states that can then spread to the liver and establish new tumors, according ...

Engineered probiotic heads to human trials

A probiotic bioengineered by UBC Okanagan researchers to thrive in the inflamed gut is set to enter human clinical trials in Australia this summer, capping a decade-long effort to turn a beneficial bacterium into a treatment ...

Microplastics may worsen fatty liver disease, new study suggests

Microplastics—minuscule pieces of plastic broken down from larger plastic waste—are a growing concern for human health, especially for the liver. A study from the University of Oklahoma, published in Science Advances, demonstrates ...

Beyond GLP-1s: The next chapter of obesity care

The rapid rise of GLP-1 medications such as semaglutide and tirzepatide has transformed obesity treatment. Still, experts say medications alone are not enough to address one of the nation's most pressing chronic diseases.